Protein

MCA_03490_1

Length
235 amino acids


Browser: contigC:110240-111082+

RNA-seq: read pairs 2142, FPKM 112.1, percentile rank 80.6% (100% = highest expression)

Protein function

KEGG:K17759AIBP NAD(P)H-hydrate epimerase [EC:5.1.99.6]
EGGNOG:0PJKFFG09439.1Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity)
SGD closest match:S000005144YNL200CNAD(P)H-hydrate epimerase
CGD closest match:CAL0000191549CAALFM_C102220CANAD(P)H-hydrate epimerase

Protein alignments

%idAln lengthE-value
MIA_03264_170.34%2366e-118MIA_03264_1
A0A060TD57_BLAAD62.98%2359e-103NAD(P)H-hydrate epimerase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D04598g PE=3 SV=1
UniRef50_C7Z50852.32%2372e-81NAD(P)H-hydrate epimerase n=66 Tax=Fungi TaxID=4751 RepID=NNRE_NECH7
A0A0J9XAM8_GEOCN53.88%2454e-82NAD(P)H-hydrate epimerase OS=Geotrichum candidum GN=BN980_GECA07s02925g PE=3 SV=1
A0A1E4TMB5_9ASCO59.05%2109e-76Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30917 PE=4 SV=1
NNRE_YARLI51.90%2372e-73NAD(P)H-hydrate epimerase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0B23122g PE=3 SV=1
NNRE_YEAST48.77%2442e-72NAD(P)H-hydrate epimerase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YNL200C PE=1 SV=1
NNRE_CANAL47.43%2532e-68NAD(P)H-hydrate epimerase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_C102220CA PE=3 SV=2
A0A1E3PJG1_9ASCO43.13%2628e-63NAD(P)H-hydrate epimerase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_70556 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3377

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 235

Detailed signature matches

    1. PF03853 (YjeF_N)
    2. MF_01966 (NADHX_epi...)
    3. SSF64153 (YjeF N-te...)
    4. PS51385 (YJEF_N)

Protein sequence

>MCA_03490_1
MKYLTASIAAAVDKELMSTQAFSLDQLMELAGLSVAQAIYRVQPPEKDKKNRVLILAGPGNNGGDGLVACRHLFLWGYNP
SLYYPKKSKHVHLERLETQLTNLGIPKISSLQELEEIISTKSTDHIVDALFGFSFKPPMRDPFDKVIDLLAKYQSEIPIT
AVDIPSSWDVDQGPLENGIKYHPDYLVSLTGPKPAAKYFKGKQHFVGGRFISKEFAKKWGFEVPDYEGDDQICKI

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.