Protein

MIA_03258_1

Length
460 amino acids

Browser: contig04:701062-702509-

Protein function

EGGNOG:0PFIXFG05901.1CAAX prenyl protease
SGD closest match:S000003878STE24CAAX prenyl protease 1
CGD closest match:CAL0000184268STE24Zinc metalloprotease

Protein alignments

%idAln lengthE-value
MCA_03868_172.222%4680.0MCA_03868_1
A0A0J9X2L8_GEOCN61.339%4633.54e-170Similar to Saccharomyces cerevisiae YJR117W STE24 Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation OS=Geotrichum candidum GN=BN980_GECA01s03651g PE=4 SV=1
UniRef50_A0A0J9X2L861.339%4637.24e-167Similar to Saccharomyces cerevisiae YJR117W STE24 Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X2L8_GEOCN
A0A060TH60_BLAAD51.422%4576.52e-141ARAD1D28336p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D28336g PE=3 SV=1
A0A1D8PL01_CANAL51.214%4534.21e-136Zinc metalloprotease OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=STE24 PE=4 SV=1
A0A1E3PQR3_9ASCO48.817%4652.05e-135Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82021 PE=4 SV=1
A0A167F073_9ASCO50.227%4406.02e-122Ste24p OS=Sugiyamaella lignohabitans GN=STE24 PE=3 SV=1
A0A1E4TJI2_9ASCO45.495%4551.86e-119Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_42520 PE=3 SV=1
STE24_YEAST48.238%4542.21e-114CAAX prenyl protease 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STE24 PE=1 SV=1
Q6C243_YARLI43.468%4443.23e-99YALI0F11033p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F11033g PE=4 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1126

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 460

Detailed signature matches

  1. Family IPR027057
    CAAX prenyl protease 1
    1. cd07343 (M48A_Zmpst...)
  2. Domain IPR032456
    CAAX prenyl protease 1, N-terminal
    1. PF16491 (Peptidase_...)
  3. Domain IPR001915
    Peptidase M48
    1. PF01435 (Peptidase_M48)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:3.30.20...
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)

Residue annotation

  1. Zn binding site cd...
  2. active site cd07343

Protein sequence

>MIA_03258_1
MDFFSKLATVAEIPGFNWKGLVVAFTAGQFAFDTYLNIRQYNFLKNDKPLTPEDGDEETFFKTQKYQLTKQRFSIFTGAY
GFLTNVAFLKFNVLPKLYYFTSSFLSKYAVKFGFLKWLASPTPQSVVTFLALQVLSSIISLPLSYYSTFVIEEKFGFNKQ
TKALFVADFLKTQILSFVIGTPIILGFVKIIEYFGDAFFLYVWSFFFVVQIFMMTIAPIVIMPLFNKFTPLEDGSLKTKI
ENLAKSLSFPLSKLFVIDGSKRSSHSNAFFTGLPWSKRIVLFDTLIEQASSDEEIVAVIGHEIGHWAKNHLAKTLVVLQG
NLSLIFFLFSAFFRNKSFYQSFGFDTTSPTSLFADRNNLPIIIGFILFLDILKPLEFFTTFGSNLLSRKHEYEADEYATD
LGMGEDLSSGLITLFKENKSSARSDPLYSAYHYSHPLLPERLAAIRARIESNKAAEKKDQ

GO term prediction

Biological Process

GO:0006508 proteolysis
GO:0071586 CAAX-box protein processing

Molecular Function

GO:0004222 metalloendopeptidase activity
GO:0008233 peptidase activity

Cellular Component

None predicted.