Protein

MCA_03868_1

Length
465 amino acids

Gene name: STE24

Description: CAAX prenyl protease 1; zinc metalloprotease

Browser: contigC:1342019-1343479-

RNA-seq: read pairs 3356, FPKM 89.0, percentile rank 77.0% (100% = highest expression)

Protein function

Annotation:STE24CAAX prenyl protease 1; zinc metalloprotease
KEGG:K06013STE24 STE24 endopeptidase [EC:3.4.24.84]
EGGNOG:0PFIXFG05901.1CAAX prenyl protease
SGD closest match:S000003878STE24CAAX prenyl protease 1
CGD closest match:CAL0000184268STE24Zinc metalloprotease

Protein alignments

%idAln lengthE-value
MIA_03258_172.22%4680.0MIA_03258_1
A0A0J9X2L8_GEOCN61.97%4680.0Similar to Saccharomyces cerevisiae YJR117W STE24 Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation OS=Geotrichum candidum GN=BN980_GECA01s03651g PE=4 SV=1
UniRef50_A0A0J9X2L861.97%4680.0Similar to Saccharomyces cerevisiae YJR117W STE24 Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X2L8_GEOCN
A0A060TH60_BLAAD54.25%4599e-162ARAD1D28336p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D28336g PE=3 SV=1
A0A1E3PQR3_9ASCO53.55%4659e-156Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82021 PE=4 SV=1
A0A1D8PL01_CANAL51.54%4544e-149Zinc metalloprotease OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=STE24 PE=4 SV=1
A0A167F073_9ASCO49.66%4411e-136Ste24p OS=Sugiyamaella lignohabitans GN=STE24 PE=3 SV=1
A0A1E4TJI2_9ASCO47.53%4651e-131Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_42520 PE=3 SV=1
STE24_YEAST47.23%4515e-125CAAX prenyl protease 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STE24 PE=1 SV=1
Q6C243_YARLI44.97%4472e-118YALI0F11033p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F11033g PE=4 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0354

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 465

Detailed signature matches

  1. Family IPR027057
    CAAX prenyl protease 1
    1. cd07343 (M48A_Zmpst...)
  2. Domain IPR032456
    CAAX prenyl protease 1, N-terminal
    1. PF16491 (Peptidase_...)
  3. Domain IPR001915
    Peptidase M48
    1. PF01435 (Peptidase_M48)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:3.30.20...
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)

Residue annotation

  1. active site cd07343
  2. Zn binding site cd...

Protein sequence

>MCA_03868_1
MDFYSKLAQVADIPGFNWKGLVLGFTAGHYVFETYLNYRQYKFLLNDKPSKDLEGLSDEETFRKTQTYQIAKQKFSIISG
VYEFVQNFATIQFNILPKIYYATGRFLSLYAPKYAITRWIFGPIGLGPTPQSVLTFLTLQLITSIINLPVSYYSTFVLEE
RFGFNKQTKKIFFTDILKGQALSFIIGTPVMLGFVKIVEYFGDSFFAYLWAFFFALQIFMMTIAPVVIMPLFNKFTPLED
GSLKTKIEALAKSLNFPLSKLFVIDGSKRSSHSNAFFTGLPWSKRIVLYDTLIEQSSEEEIVAVLGHEIGHWAKSHLFKT
LVVSQTHISLIFFLFSAFFRNVSFYQSFGFDTFSAETILTGGKPQLPILMGFMLFMDILKPMEFVTTFLTNLLSRKHEYE
ADEFATDLGMGEDLCTGLTTLFKENLSSANSDPLYSAYHYSHPLLPERLRAIKLRMAEAEGKKDK

GO term prediction

Biological Process

GO:0006508 proteolysis
GO:0071586 CAAX-box protein processing

Molecular Function

GO:0004222 metalloendopeptidase activity
GO:0008233 peptidase activity

Cellular Component

None predicted.