Protein

MIA_03235_1

Length
166 amino acids


Browser: contig04:628729-629489+

Protein function

EGGNOG:0PN8KATP16Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits
SGD closest match:S000002162ATP16ATP synthase subunit delta, mitochondrial
CGD closest match:CAL0000197920ATP16F1F0 ATP synthase subunit delta

Protein alignments

%idAln lengthE-value
MCA_00900_185.542%1666.23e-104MCA_00900_1
A0A0J9XJP2_GEOCN80.120%1663.55e-89Similar to Saccharomyces cerevisiae YDL004W ATP16 Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase OS=Geotrichum candidum GN=BN980_GECA24s00725g PE=3 SV=1
A0A060T751_BLAAD62.745%1532.16e-65ARAD1B20504p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B20504g PE=3 SV=1
UniRef50_G9P66258.896%1631.80e-55F1F0 ATP synthase delta chain mitochondrial n=56 Tax=leotiomyceta TaxID=716546 RepID=G9P662_HYPAI
A0A1D8PUD2_CANAL49.686%1596.58e-53F1F0 ATP synthase subunit delta OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ATP16 PE=3 SV=1
A0A1E3PNB8_9ASCO62.185%1193.39e-50Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_8412 PE=4 SV=1
A0A1E4TF72_9ASCO50.000%1527.34e-49Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_24048 PE=3 SV=1
ATPD_YEAST51.656%1515.36e-46ATP synthase subunit delta, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATP16 PE=1 SV=1
Q6C877_YARLI63.636%1216.28e-46YALI0D22022p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D22022g PE=1 SV=1
A0A167FYE5_9ASCO72.603%738.05e-35F1F0 ATP synthase subunit delta OS=Sugiyamaella lignohabitans GN=ATP16 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9922
Predicted cleavage: 36

Protein family membership

Domains and repeats

1 20 40 60 80 100 120 140 166

Detailed signature matches

    1. MF_00530 (ATP_synth...)
    2. cd12152 (F1-ATPase_...)
    1. SSF51344 (Epsilon s...)
    2. PF02823 (ATP-synt_DE_N)
Unintegrated signatures no IPR
Unintegrated signatures

Residue annotation

  1. gamma subunit inte...
  2. epsilon subunit in...
  3. LBP interface cd12...

Protein sequence

>MIA_03235_1
MMYLARSVARKALPAMARPSMFVARRGFAEAVPADKLRLSLALPHETLYENTDVVQVNIPSTAGDLGILADHVPTIQQLR
PGLVEIIESGGKSTQFFVSGGFATVSEGSKIAVNVVEAYAPEDFSSEAVKSLTAEAQKNATSSDEAVSTEAKIQLEVLES
LAYYVK

GO term prediction

Biological Process

GO:0015986 ATP synthesis coupled proton transport

Molecular Function

GO:0046933 proton-transporting ATP synthase activity, rotational mechanism

Cellular Component

GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)