Protein

MCA_00900_1

Length
166 amino acids


Gene name: ATP16

Description: ATP synthase subunit delta, mitochondrial

Browser: contigA:2835194-2836382+

RNA-seq: read pairs 27605, FPKM 2042.4, percentile rank 97.8% (100% = highest expression)

Protein function

Annotation:ATP16ATP synthase subunit delta, mitochondrial
KEGG:K02134ATPeF1D F-type H+-transporting ATPase subunit delta
EGGNOG:0PN8KATP16Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits
SGD closest match:S000002162ATP16ATP synthase subunit delta, mitochondrial
CGD closest match:CAL0000197920ATP16F1F0 ATP synthase subunit delta

Protein alignments

%idAln lengthE-value
MIA_03235_185.54%1663e-102MIA_03235_1
A0A0J9XJP2_GEOCN79.52%1662e-86Similar to Saccharomyces cerevisiae YDL004W ATP16 Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase OS=Geotrichum candidum GN=BN980_GECA24s00725g PE=3 SV=1
A0A060T751_BLAAD63.40%1532e-62ARAD1B20504p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B20504g PE=3 SV=1
UniRef50_A5E6L855.70%1587e-55ATP synthase delta chain, mitochondrial n=4 Tax=Saccharomycetales TaxID=4892 RepID=A5E6L8_LODEL
A0A1D8PUD2_CANAL54.09%1596e-55F1F0 ATP synthase subunit delta OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ATP16 PE=3 SV=1
A0A1E4TF72_9ASCO50.32%1555e-47Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_24048 PE=3 SV=1
A0A1E3PNB8_9ASCO63.87%1195e-47Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_8412 PE=4 SV=1
ATPD_YEAST55.38%1302e-45ATP synthase subunit delta, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATP16 PE=1 SV=1
Q6C877_YARLI64.17%1204e-45YALI0D22022p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D22022g PE=1 SV=1
A0A167FYE5_9ASCO73.97%737e-34F1F0 ATP synthase subunit delta OS=Sugiyamaella lignohabitans GN=ATP16 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9884
Predicted cleavage: 36

Protein family membership

Domains and repeats

1 20 40 60 80 100 120 140 166

Detailed signature matches

    1. MF_00530 (ATP_synth...)
    2. cd12152 (F1-ATPase_...)
    1. SSF51344 (Epsilon s...)
    2. PF02823 (ATP-synt_DE_N)

Residue annotation

  1. gamma subunit inte...
  2. epsilon subunit in...
  3. LBP interface cd12...

Protein sequence

>MCA_00900_1
MSFLARSVARKAFPAIARPSVMIARRGFAEAVPADKLRLSLALPHTTLYENSDVVQVNLPSTAGDLGILADHVPTIQQLR
PGLVEIIESTGNSTSYFVSGGFATVSEGSKLAINVVEAFKPEDFSAEAVKNLTAEAQKNSTSSDVAVAEEAKIQLEVLES
LAYYVK

GO term prediction

Biological Process

GO:0015986 ATP synthesis coupled proton transport

Molecular Function

GO:0046933 proton-transporting ATP synthase activity, rotational mechanism

Cellular Component

GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)