Protein

MIA_03200_1

Length
1,581 amino acids


Browser: contig04:539283-544098+

Protein function

EGGNOG:0PFNEGEA2Guanine nucleotide exchange factor
SGD closest match:S000000748GEA2ARF guanine-nucleotide exchange factor 2
CGD closest match:CAL0000192304GEA2Arf family guanine nucleotide exchange factor

Protein alignments

%idAln lengthE-value
MCA_02917_154.833%16760.0MCA_02917_1
A0A0J9XE61_GEOCN52.369%15620.0Similar to Saccharomyces cerevisiae YEL022W GEA2 Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) OS=Geotrichum candidum GN=BN980_GECA12s00483g PE=4 SV=1
UniRef50_A0A0J9XE6152.369%15620.0Similar to Saccharomyces cerevisiae YEL022W GEA2 Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XE61_GEOCN
A0A060T9W3_BLAAD42.156%15680.0ARAD1B02926p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B02926g PE=4 SV=1
A0A167CZ00_9ASCO51.548%7430.0Arf family guanine nucleotide exchange factor GEA2 OS=Sugiyamaella lignohabitans GN=GEA2 PE=4 SV=1
A0A1E3PFU7_9ASCO32.813%16670.0Sec7-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_7215 PE=4 SV=1
Q6C5B2_YARLI36.118%12570.0YALI0E19536p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E19536g PE=4 SV=1
A0A1E4TM80_9ASCO33.301%10271.92e-140Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_147690 PE=4 SV=1
GEA2_YEAST28.442%14311.24e-138ARF guanine-nucleotide exchange factor 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GEA2 PE=1 SV=1
A0A1D8PJ74_CANAL35.224%7584.22e-105Arf family guanine nucleotide exchange factor OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GEA2 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0037

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1400 1581

Detailed signature matches

    1. SSF48371 (ARM repeat)
    1. PF12783 (Sec7_N)
    1. SM00222 (sec7_5)
    2. SSF48425 (Sec7 domain)
    3. PS50190 (SEC7)
    4. PF01369 (Sec7)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)
  2. cd00171 (Sec7)
  3. mobidb-lite (disord...)

Residue annotation

  1. active site/putati...

Protein sequence

>MIA_03200_1
MDSYNSKTSQLSSISVDPIFLVTNECIYITSAMRKNARWSQSSMAAILGVSSIADNAEGDIASRWGLRGRSSSGGDNPLV
AGFARLRADLTQVTDIKEISADAIFAPFLEVISSQATTGPITFIALSSINKFLDYKVVSPESQNFQLVISQLVFSITHCR
FEATDQSEDDTVLLKILNIMELLVCSFGNDYLSDESLCDIIETCLSMACQIKRGDLLRRSAEMTMIKLTEAVFARLAELD
LEDDLDLLSAENLQDHLANPPPQVISPSEESPETETVATNTNNNPQDIPVEITSVNDTIHTSDDPVDLDTLEIPTAIASV
AATNGQKTFQKYGIASIREYLRVLISIIDSANAHQYTDTTRIMVLHLINVAFEVAGSQMARFPSLLDLTTTTLLKHLLQF
TRSESPHLLQKSLRVSSTIFHTSRRHLKLQQEMFLTYLLTCLSPIAEIPKEEGVDDIFYNGVPSIPRAVINASPHPSKVS
TPVGGKSATASSTTSDGAQLPSFINMRSPDAREMMVEALTGLTRIPNYFVDLFVNYDCDVDRADLCEDLIGFLCRNAYPD
SATWSTSSVPPLCLDALLAFLSSLAYRLDNNDYPEGDKEISSASLQNKQRKRIVIEVTDLFNTKPKKGIPAMVERGLIPD
DKPANVLKFLQSSGRINKKILGEFLAAPQNSEYLDLFIKSFNFENKSLDEAMRDLCTAIRLPGESQQIERIMEKFAERYC
EFKSNIEFVADKDAAFILSYAVIMLNTDLHNPQVKRHMTNEEFSRNLRKMNAGEDFSPDYLVSVYSAIKDKEIVMPEEHD
DDESFDHMWRELLIKAPLAGTAVHLGSGVFDKEIFQASWQPIVSTLSYIFATATEDTVFSRVIKGFDDIAQISNRYKIAG
VTDQIIYSLGKISTLTYGNLSVPPSTIEMTTEADEKIVVSELSVQFGEDFKAQLASIILFRIAKSNSCFISESWSQILVL
ITNLYLHSLFSALSQNLQYGIPPLPFVKPVHVLQKGKSSKDAGLFSTLSSYLTGYNDSIPEPTDEEVESTLSAVDSIRSF
ELPEFFEEALNTSWEQIVNSGLEVIPSLDTLSPPNRQKFYPSILFLLDIVTLAAIHSKDSTIQKKVFEVFKQYISEWEIS
DSSFLTRCIIYYLVLLRNSSITMEDDLLEALSIVADIKESVLKQCIGKLVDPLISLADEGSWTSELVLKKSPAYWQLFKL
AASSRDCTQKVFDFVEKLAAASKPNHGGPICEDNLSGVLDVFGEIVSVGACGAQLEQNKAAIAYEFKKQYDQQTAIKKAK
EVIANMEVDVKRSMHALDTIASLEPYVEKLADEAEEADNGKQSAWAKLWLPYVRTLSQQCINPSRRIRHQAFAYFQKTCL
SPFLQTRADFDWILLFDEELFPLFDALLNAEVYETDPKGMNHTRLQAAALLCKVFLQYVAGNFESQRAALAGEGVAVEEL
RQARNAELFKYWMRVLDTIDRLMNSAGKQSQLQGANKTQRDAPSKGHRSSNSNASNTANETLEALEESVVESVKNLLLVI
KASELPQSDEFWDETWKRVEAIWPGLRADLRARTGVSEEPKSEDKDEPETGAEKESTEQVL

GO term prediction

Biological Process

GO:0032012 regulation of ARF protein signal transduction

Molecular Function

GO:0005086 ARF guanyl-nucleotide exchange factor activity
GO:0005488 binding

Cellular Component

None predicted.