Protein
MCA_02917_1
Length
1,716 amino acids
Gene name: GEA2
Description: ARF guanine-nucleotide exchange factor 2
Browser: contigB:2768733-2773963-
RNA-seq: read pairs 2403, FPKM 17.3, percentile rank 37.5% (100% = highest expression)
Protein function
| Annotation: | GEA2 | ARF guanine-nucleotide exchange factor 2 | |
|---|---|---|---|
| KEGG: | K18443 | GBF1 | golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 |
| EGGNOG: | 0PFNE | GEA2 | Guanine nucleotide exchange factor |
| SGD closest match: | S000000748 | GEA2 | ARF guanine-nucleotide exchange factor 2 |
| CGD closest match: | CAL0000192304 | GEA2 | Arf family guanine nucleotide exchange factor |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03200_1 | 55.74% | 1699 | 0.0 | MIA_03200_1 |
| A0A0J9XE61_GEOCN | 49.70% | 1332 | 0.0 | Similar to Saccharomyces cerevisiae YEL022W GEA2 Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) OS=Geotrichum candidum GN=BN980_GECA12s00483g PE=4 SV=1 |
| UniRef50_A0A0J9XE61 | 49.70% | 1332 | 0.0 | Similar to Saccharomyces cerevisiae YEL022W GEA2 Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XE61_GEOCN |
| A0A060T9W3_BLAAD | 41.06% | 1342 | 0.0 | ARAD1B02926p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B02926g PE=4 SV=1 |
| A0A167CZ00_9ASCO | 46.95% | 803 | 0.0 | Arf family guanine nucleotide exchange factor GEA2 OS=Sugiyamaella lignohabitans GN=GEA2 PE=4 SV=1 |
| Q6C5B2_YARLI | 33.54% | 1115 | 9e-162 | YALI0E19536p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E19536g PE=4 SV=1 |
| A0A1E3PFU7_9ASCO | 37.99% | 637 | 5e-108 | Sec7-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_7215 PE=4 SV=1 |
| A0A1E4TM80_9ASCO | 33.92% | 802 | 5e-99 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_147690 PE=4 SV=1 |
| A0A1D8PJ74_CANAL | 32.50% | 637 | 1e-89 | Arf family guanine nucleotide exchange factor OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GEA2 PE=4 SV=1 |
| GEA2_YEAST | 27.11% | 970 | 5e-83 | ARF guanine-nucleotide exchange factor 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GEA2 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0143
Protein family membership
None predicted.
Domains and repeats
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Domain
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Domain
1
200
400
600
800
1000
1200
1400
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1716
Detailed signature matches
no IPR
Unintegrated signatures
-
-
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cd00171 (Sec7)
-
mobidb-lite (disord...)
Residue annotation
-
active site/putati...
Protein sequence
>MCA_02917_1 MSLSTPISVDPIFLITNECIYITSAMRKNSRWAQSGMAAILGVSSISDDNDGLASRWGLKAKPTSGRDNPLIAGFAKLRA DLTNALDISEIPADAIFSPFLEVIGSQSTTGPITFIALTAISKFLDYNVVSSKSPNIQTAVAQLSFSITHCRFEATDQAE DDAVLLKILGIMETLVCGFGTEYLNDESLCDIIETCLSMACQMRRGDLLRRSAEMTMIKLTETVFSRLYDIEATSEENTN ATASTNLQEHLSNPVPEYCDQQKDQAEAAERENAPEIRTASVQTITDEVEQEYKPEESVTVDNDDTKDPAAPPDTSSRNR NISITSSNDTVHVDNMLPSNTFVSPNSAPHLDAVPPTPGDIQSFPFQRYGLPSIREYLRVLISIIDSANARQYTDATRVM VLHLINVVFEVAGTQIVKFPSLLELISESLLKHLLQLIKSENPYLLQKSLRVSCTIFHTSRSHLKLQQEMYLTYLLTCLS PISDIPREEGVDEIFYNGVPNIPRTVLNASPHPSKVGTPVGGRSSNVSSNGGPVSNLKNLASANNSSANIGSAGSNGSVV GPNGKSLPSFLTIRSPEAREMMVEALTGLTRIPSFFVDLYMNYDCDVDRADLCEDLIGFLCRNAYPDSATWSTTNVPPLC LDALLAFLSSLVYRLEYTDSSYDDTQNNETKQHQKSKNRYIQGSVSSNLDEKKAVKNALEAKAHKRLVIHATEAFNQNPS DGIKVMVSSGLIPNEEPESVVEFLRKSGRINKKVLGEFVSKAKNAKYLDYFMKSYDFENKRLDEALRELCSDIRLPGESQ LIERIVEKFAEQYCSAKSNNKYVANADAAFVLSYATIMLNTDQHSPQVKVQMTNEQFTRNLRGMNNKEDFDPEYLNSIYN AIKEKEIIIPEEHDNEESFEHVWADLISKIPKAGKAPSYNTNILDKRLFELAWKPIVSTLSYIFATATEDTVFSRVLAGF DHVAQLSTRYEVPGVIDQIIYSLGKISTLTYGDLSVPPSTIELILDDEPTSDSEQEKAVVSNSKPEKITISDLSIQFGED FKAQLASVVLFRLAKSTGTKFISQSWSQILALVTNLYLHSLVPSTVSASQVKLGIPQLPPIRPRYKVEKSKFNKDAGLFS TLSSYLTGYNDSVPEPTDEEIEATLSTIDCVGSFDLRDFLEEALVSSPLQIVHGAIQILPNISNLPPPNKARFYPSSLYL LEFSIVASINSADAEVQRLVLECIDIYISLWEVLEKEFLTLCIVFYLVLLRQGLAELKPQLLSVLDSIANIRDVVLISCI PKLIKPLVALTEDESWTRDIVLNESKSFWKLIKLAAENRESAQSAYDFVKNLVNNNSIDKETGKAILVTPSNIVDILDVF GEIISIGACGAQLEQDKTAIAYEFRKQYDQQTAIKKAKEVIASMEMDVNRSLEALDTLKKMDSFIAEFDANGDLSTTSST SALKDLWLPYVRTLSQQCINPSRKVRSHAFHYFQEIFISSVLHSKADFDWKMMLSEGLFPLLEALLKAEVYETDSKGMSY TRLQSASLLCKVFLQYVVRQPPSGEHNQEDIFELWIKVLDTLDRLINSTGTRRRGHADISKKSTYNYNNTHKNVQPNPNQ IHSEVYNMTNVEAIESFEESVIESVKNLLLVMKSSEPPQSDYFWAETWKRIESIMPGLKEDLEMKVQSSQQVNTSPSLEK DTNQLEKEDETLPQENNTEGSIELEKDSKVEEENIV
GO term prediction
Biological Process
GO:0032012 regulation of ARF protein signal transduction
Molecular Function
GO:0005086 ARF guanyl-nucleotide exchange factor activity
GO:0005488 binding
Cellular Component
None predicted.