Protein

MIA_03182_1

Length
874 amino acids

Browser: contig04:484751-487376-

Protein function

EGGNOG:0PIM3FG06426.1HECT domain protein
SGD closest match:S000003109HUL5Probable E3 ubiquitin-protein ligase HUL5
CGD closest match:CAL0000198465orf19.5892Putative E3 ubiquitin-protein ligase

Protein alignments

%idAln lengthE-value
MCA_03945_126.190%10084.51e-67MCA_03945_1
A0A060TE37_BLAAD28.953%4495.57e-43ARAD1D04730p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D04730g PE=4 SV=1
UniRef50_A0A060TE3728.953%4491.38e-39ARAD1D04730p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060TE37_BLAAD
A0A0J9X2R9_GEOCN27.041%5882.01e-41Similar to Saccharomyces cerevisiae YJR036C HUL4 Protein with similarity to hect domain E3 ubiquitin-protein ligases OS=Geotrichum candidum GN=BN980_GECA01s05433g PE=4 SV=1
Q6C8U2_YARLI26.036%3383.10e-21YALI0D16984p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D16984g PE=4 SV=1
Q5ANK9_CANAL23.596%4454.36e-18Putative E3 ubiquitin-protein ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5892 PE=4 SV=1
HUL5_YEAST24.086%4652.68e-17Probable E3 ubiquitin-protein ligase HUL5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HUL5 PE=1 SV=1
A0A1E3PR22_9ASCO24.928%3499.72e-17Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_39297 PE=4 SV=1
A0A1E4TJX7_9ASCO25.294%3407.34e-16Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_14432 PE=4 SV=1
A0A170QY39_9ASCO26.273%3734.39e-15E3 ubiquitin-protein ligase TOM1 OS=Sugiyamaella lignohabitans GN=TOM1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0418

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 874

Detailed signature matches

  1. Domain IPR032353
    Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain
    1. PF16558 (AZUL)
  2. Domain IPR000569
    HECT domain
    1. PF00632 (HECT)
    2. SSF56204 (Hect, E3 ...)
    3. SM00119 (hect_3)
    4. PS50237 (HECT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:3.30.24...
  3. G3DSA:3.90.17...
  4. NON_CYTOPLASM... (N...)
  5. TMhelix
  6. TRANSMEMBRANE (Tran...)
  7. mobidb-lite (disord...)

Protein sequence

>MIA_03182_1
MQKQVHYYAGSDPKPLSQAENTSKLVVRYLYQILHGCGSPSCTQLTCRSAKKSSAVFPNQTFTPFAALNLAIHLTSLRGC
NALCMLLREPILPPAVAALLCEEEPLRSKVFLKAFQRSERRRKKKEPGAKDPKLLRQPLSRYTKKTSSSLDAIPEEHSAE
HTKRAPIKKKHSSSVSAASLEIPTPVFGYKFNLSDPIPIPWIPKKERQGRALKAHYLDFGLITKRVPRNGTLDLTSVDPT
GEKTATTLITIFTCRYLWDDSVANIGLRRCILGECFFPSLDKLVEWAMNNLDKNKQLFFVRTVSDALVVLPVLRPLVIQQ
IRSFELNNAGRELISYLTRIVELAHPSNVQYINVPIAFSAFNGLHFSKPYSIACSKKAFQTWRSFSSSSSSPYIDHMYKS
MHCNALPFSRFMPDLKLPETKIGPYPLLDFVPDSPRVIIKGLLTGKKRPLLIKYPSDPVRSNYLSTSLHMISDYPKFIPF
ETRYKIFRYKMFEMMEMSKTCSRAVKSVIFKTFNSELNVWMLSFFKITVFREYLIESAFLNLSDYFLFGVPRTFNLPFRV
KYGNTGEIAVDEGGVQVEFFQSFGAEVMKKEGFFLETDDESTVAWFPKVLIRNLTEYLFLGIFLGIAIYNGCTVSISLPL
FFYKHLKMCVHGDTEFNSYTFTETMDYLKEIYPSVGKSFQMMNDDPSTIDEMEIPLNDTHNNTEYVTSKNYRKFISNWVQ
ERIKKKCHLIKTIADGIFLVVEESHLTGFSALELRQLIEGNHVVTAADLEANVAYGGNFTPNSPTVILFWKIVKTRFSND
DTANLFEFVTGSNRVPPSRKFDFIIQSSTSAPNLIPTASVCFSILNLSEEYKSIGHLETMIRLAIENSKGFGLV

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0004842 ubiquitin-protein transferase activity

Cellular Component

None predicted.