Protein
MCA_03945_1
Length
954 amino acids
Description: Ubiquitin-protein ligase E3A
Browser: contigC:1582003-1584868+
RNA-seq: read pairs 1258, FPKM 16.3, percentile rank 35.8% (100% = highest expression)
Protein function
| Annotation: | Ubiquitin-protein ligase E3A | ||
|---|---|---|---|
| KEGG: | K10587 | UBE3A | ubiquitin-protein ligase E3 A [EC:2.3.2.26] |
| EGGNOG: | 0PIM3 | FG06426.1 | HECT domain protein |
| SGD closest match: | S000000927 | RSP5 | E3 ubiquitin-protein ligase RSP5 |
| CGD closest match: | CAL0000198465 | orf19.5892 | Putative E3 ubiquitin-protein ligase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03182_1 | 26.49% | 1004 | 1e-68 | MIA_03182_1 |
| A0A060TE37_BLAAD | 27.33% | 472 | 2e-34 | ARAD1D04730p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D04730g PE=4 SV=1 |
| UniRef50_A0A146N743 | 28.31% | 438 | 6e-30 | Ubiquitin-protein ligase E3A n=4 Tax=Cyprinodontiformes TaxID=28738 RepID=A0A146N743_FUNHE |
| A0A0J9X2R9_GEOCN | 25.81% | 616 | 3e-31 | Similar to Saccharomyces cerevisiae YJR036C HUL4 Protein with similarity to hect domain E3 ubiquitin-protein ligases OS=Geotrichum candidum GN=BN980_GECA01s05433g PE=4 SV=1 |
| A0A167DCT0_9ASCO | 27.27% | 440 | 1e-27 | Putative E3 ubiquitin-protein ligase HUL4 OS=Sugiyamaella lignohabitans GN=HUL4 PE=4 SV=1 |
| Q5ANK9_CANAL | 26.33% | 433 | 6e-21 | Putative E3 ubiquitin-protein ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5892 PE=4 SV=1 |
| Q6C8U2_YARLI | 24.23% | 454 | 7e-21 | YALI0D16984p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D16984g PE=4 SV=1 |
| A0A1E4TDD7_9ASCO | 26.95% | 423 | 7e-21 | E3 ubiquitin-protein ligase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_144090 PE=4 SV=1 |
| A0A1E3PR22_9ASCO | 26.33% | 414 | 2e-19 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_39297 PE=4 SV=1 |
| RSP5_YEAST | 25.47% | 424 | 3e-18 | E3 ubiquitin-protein ligase RSP5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RSP5 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0197
Predicted cleavage: 17
Protein family membership
None predicted.
Domains and repeats
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Domain
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954
Detailed signature matches
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PF16558 (AZUL)
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no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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TRANSMEMBRANE (Tran...)
Protein sequence
>MCA_03945_1 MKAPENRFFAGTVPGAFGVEDIITQLIARYLYQILHGCEDLNCNQPTCKTNFTYFPGKRIKASAAFNMAAHLASLRGPTA LCQKLLPDRLHYKIAYMIDESQPLASRIYIQRLETENNTKRPKQRRKKTVIPQGTDLILHIKNCYNNRHMVVMLCARTVP YAPWTFEWMHDNSVKLPWKYLAPEPPTRHSPQTDEDNTLDKDKLHRELKIIDPSGMRTAATVIHLLTHRVDWRGNMVAKY GLENCTSVLLLYVRYLFEYCASRFQLNKNDTDAIFLSRAIVNLATSAAILFRAYLSAEEVRNNVYFHHIKLIYAAMDLYP KNYGFPMTTHLRFMPLFFAEFSEIFSTRIIEACLYKTALTWHHNSPASQSPYFHQLIASKLINNDKKYLELFSFYLGTRQ PFLPSQFVNVQRTPSSQMVLRNLNQPHPPPVRNRATRMLDLKVPVHTNTRLLALRFANSRIMSFSRYCGNIATYAVFPIR EMVEILKQDEITTTMLSYMMMQDPTRSFSEDILSQLFAPLEYQIFHIRNALPLKIDPDNVLKSALQEIDLARDSRLPYLF TVPLKVQFIGSEITADQGGVQVEFFRLLGIELMNPHNGFFVIDSDTKQAWFPEEGEISAKKIRKYENIGILFALAIFNGC AITVDFPTMFYRYLIKPFLFAGPEDSTVVDRFLNDENAVVSCFMDILPSHGKVFKQFKEDPDSIEAMQIPFVRLNNTKTT VHATDQVVSKSNYHEYIRVMAYDRMIINGFAKLNHILRGMQRIFPATYSQFFKKNDNSPAFQCLFNTVPPHIPVSAMEES QPFNLFYNFNSSELQVLMEGLRTVTVDDFKANAMYVGYDANKSVQIKWFWEILSTSFSQEDLILLLKFVTGSDRIPGSRK FWFIIQKFKTDEDVYFDDKTDAYIGSDSTDQSTERLPSSSVCFSTLYLPQYSTKEKLEKKLRLAVQYSTGFGLV
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
Cellular Component
None predicted.