MIA_03168_1

Protein

Length

636 amino acids

Protein function

EGGNOG:	0PGPR	DTR1	dityrosine transporter
SGD closest match:	S000000384	DTR1	Dityrosine transporter 1
CGD closest match:	CAL0000192608	CAALFM_CR04620CA	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
MCA_01690_1	74.330%	448	0.0	MCA_01690_1
A0A0J9XJZ5_GEOCN	66.742%	445	0.0	Similar to Saccharomyces cerevisiae YBR180W DTR1 Putative dityrosine transporter OS=Geotrichum candidum GN=BN980_GECA24s00824g PE=4 SV=1
A0A1D8PST5_CANAL	48.289%	526	1.55e-154	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR04620CA PE=4 SV=1
UniRef50_B9WLR1	48.295%	528	2.24e-146	Dityrosine transporter, putative n=7 Tax=Saccharomycetales TaxID=4892 RepID=B9WLR1_CANDC
DTR1_YEAST	43.694%	444	9.43e-104	Dityrosine transporter 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DTR1 PE=1 SV=1
A0A167F432_9ASCO	29.832%	476	1.64e-53	Qdr2p OS=Sugiyamaella lignohabitans GN=QDR2 PE=4 SV=1
A0A060SY62_BLAAD	30.330%	455	8.89e-53	ARAD1A18260p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A18260g PE=4 SV=1
A0A1E3PGV9_9ASCO	28.355%	462	8.79e-49	MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83453 PE=4 SV=1
Q6C300_YARLI	28.008%	482	1.24e-41	YALI0F03751p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F03751g PE=4 SV=1
A0A1E4TA81_9ASCO	25.676%	444	8.96e-38	Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_13925 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0269

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
77 - 529
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 636

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  103 - 486
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  97 - 525
  
  PROSITE profiles
  PS50850 (MFS)
2. SSF103473 (MFS gene...)
  
  77 - 529
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
3. cd06174 (MFS)
  
  98 - 521
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

212 - 222

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

151 - 161

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

455 - 458

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

388 - 407

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

522 - 636

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 95

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

273 - 324

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

79 - 307

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

315 - 538

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

479 - 497

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

247 - 251

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

346 - 364

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

117 - 127

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

182 - 186

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

429 - 433

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

96 - 118

TMHMM
TMhelix (TMhelix)

133 - 155

TMHMM
TMhelix (TMhelix)

433 - 455

TMHMM
TMhelix (TMhelix)

188 - 210

TMHMM
TMhelix (TMhelix)

364 - 386

TMHMM
TMhelix (TMhelix)

499 - 521

TMHMM
TMhelix (TMhelix)

467 - 489

TMHMM
TMhelix (TMhelix)

250 - 272

TMHMM
TMhelix (TMhelix)

407 - 429

TMHMM
TMhelix (TMhelix)

327 - 349

TMHMM
TMhelix (TMhelix)

162 - 184

TMHMM
TMhelix (TMhelix)

223 - 245

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

325 - 345

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

459 - 478

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

434 - 454

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

96 - 116

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

408 - 428

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

187 - 211

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

162 - 181

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

252 - 272

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

365 - 387

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

498 - 521

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

223 - 246

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

128 - 150

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
mobidb-lite (disord...)

576 - 636

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 84

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

112G

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

115Y

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

116L

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

117P

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

119L

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

120Q

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

137I

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

140F

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

141M

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

144F

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

148P

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

149L

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

151W

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

152A

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

199A

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

200S

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

203Q

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

204S

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

207A

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

208G

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

211A

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

223I

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

224A

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

227M

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

228L

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

234P

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

339F

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

342Y

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

343Y

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

346A

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

347V

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

350S

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

364V

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

368Y

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

372G

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

375L

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

379S

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

446G

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

449M

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

450T

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

453F

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

457T

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

458T

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

461T

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

471L

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

472V

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

475A

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

476S

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

479R

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

480N

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

483A

putative substrate translocation pore
112G, 115Y, 116L, 117P, 119L, 120Q, 137I, 140F, 141M, 144F, 148P, 149L, 151W, 152A, 199A, 200S, 203Q, 204S, 207A, 208G, 211A, 223I, 224A, 227M, 228L, 234P, 339F, 342Y, 343Y, 346A, 347V, 350S, 364V, 368Y, 372G, 375L, 379S, 446G, 449M, 450T, 453F, 457T, 458T, 461T, 471L, 472V, 475A, 476S, 479R, 480N, 483A
CDD
cd06174 (MFS)

Protein sequence

>MIA_03168_1
MNNFEKDPEKNTAVLPQTIIQEDSSSTLDDSDKASSTDFANKKDAEILIKASSPESDPTDKPTINKKCEASLPEAPPADP
PKPPPYTAFPLWRKRMILGLVTSAGFLGPLSGSIYLPVLQVIKKEFSISTTVANTTIAVFMIVFAFAPLLWASWADFGGR
KFLYIVSLIIYIASCICLAALPAHTAVIFVFRVVQAFGASSVQSLGAGTVADLVEPKNRASAIAVFMLGPQLGPVLGPIL
GGAIAARDDWRWIFGFLAIIGAVILLMFIFMLPETLRYLVGNGSVYENKLFVHPHLRQKKIVFDDKRFPKPPKPSLIGYL
RIMRYIPVTLVSINAGLLFATYYGIAVTYSKYLSSQYHFSTTEVGLGYIVPGVSLASGSLISGRISDKIRKRMIANHPDG
KVIPEHRLPIQIFGILVSMAGILCYGWMIDKHVHVVSVMVFSFMSGFGMTWVFVINTTYLTECAPAMPASLVAIASFFRN
SGAAISSVIIEPLISRMGVGWCFTGLAFIDFFGLAMVLALVKYGPKWRHDLDQKKLRAKAAAEEKAAAAKSVIQGPAAPM
VQEVPEIPQPAPVEVISRSRSRNSLTKTGYLTTQPMPETSTSSPMPKESPVLATQANESLVQDEPLYPKFEQQKQL

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features