MCA_01690_1

Protein

Length

632 amino acids

Gene name: DTR1

Description: Dityrosine transporter 1

Browser: contigA:5192769-5194751+

RNA-seq: read pairs 73367, FPKM 1432.1, percentile rank 97.3% (100% = highest expression)

Protein function

Annotation:		DTR1	Dityrosine transporter 1
EGGNOG:	0PGPR	DTR1	dityrosine transporter
SGD closest match:	S000000384	DTR1	Dityrosine transporter 1
CGD closest match:	CAL0000192608	CAALFM_CR04620CA	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
MIA_03168_1	75.00%	448	0.0	MIA_03168_1
A0A0J9XJZ5_GEOCN	67.26%	449	7e-176	Similar to Saccharomyces cerevisiae YBR180W DTR1 Putative dityrosine transporter OS=Geotrichum candidum GN=BN980_GECA24s00824g PE=4 SV=1
A0A1D8PST5_CANAL	54.14%	447	4e-127	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR04620CA PE=4 SV=1
UniRef50_B9WLR1	53.47%	447	8e-121	Dityrosine transporter, putative n=7 Tax=Saccharomycetales TaxID=4892 RepID=B9WLR1_CANDC
DTR1_YEAST	43.34%	443	1e-80	Dityrosine transporter 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DTR1 PE=1 SV=1
Q6C300_YARLI	28.54%	487	6e-32	YALI0F03751p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F03751g PE=4 SV=1
A0A167F432_9ASCO	29.37%	463	5e-31	Qdr2p OS=Sugiyamaella lignohabitans GN=QDR2 PE=4 SV=1
A0A060TCH4_BLAAD	27.91%	455	5e-31	ARAD1D36146p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D36146g PE=4 SV=1
A0A1E3PGV9_9ASCO	27.41%	467	1e-27	MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83453 PE=4 SV=1
A0A1E4TC15_9ASCO	30.37%	214	5e-16	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29229 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0099

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
153 - 604
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 632

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  181 - 471
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  175 - 604
  
  PROSITE profiles
  PS50850 (MFS)
2. SSF103473 (MFS gene...)
  
  153 - 604
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
3. cd06174 (MFS)
  
  176 - 600
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

601 - 632

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

535 - 545

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

351 - 403

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

230 - 240

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 173

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

467 - 486

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

287 - 297

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
Coil

629 - 632

COILS
Coil (Coil)
G3DSA:1.20.12...

141 - 377

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

391 - 617

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

319 - 329

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

425 - 443

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

260 - 264

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

508 - 512

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

566 - 576

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

198 - 208

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

247 - 269

TMHMM
TMhelix (TMhelix)

546 - 568

TMHMM
TMhelix (TMhelix)

301 - 323

TMHMM
TMhelix (TMhelix)

210 - 232

TMHMM
TMhelix (TMhelix)

175 - 197

TMHMM
TMhelix (TMhelix)

512 - 534

TMHMM
TMhelix (TMhelix)

443 - 465

TMHMM
TMhelix (TMhelix)

578 - 600

TMHMM
TMhelix (TMhelix)

328 - 350

TMHMM
TMhelix (TMhelix)

406 - 428

TMHMM
TMhelix (TMhelix)

486 - 508

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

209 - 229

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

444 - 466

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

265 - 286

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

577 - 600

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

298 - 318

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

330 - 350

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

546 - 565

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

241 - 259

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

513 - 534

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

487 - 507

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

174 - 197

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

404 - 424

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
mobidb-lite (disord...)

100 - 162

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 60

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

190G

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

193Y

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

194L

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

195P

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

197L

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

198P

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

215V

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

218F

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

219M

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

222F

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

226P

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

227L

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

229W

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

230A

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

277A

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

278S

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

281Q

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

282S

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

285A

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

286G

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

289A

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

301I

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

302S

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

305M

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

306L

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

312P

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

418F

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

421Y

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

422Y

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

425A

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

426V

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

429S

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

443V

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

447Y

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

451G

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

454L

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

458S

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

525G

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

528M

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

529T

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

532F

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

536T

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

537T

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

540T

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

550L

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

551V

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

554A

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

555S

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

558R

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

559N

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

562A

putative substrate translocation pore
190G, 193Y, 194L, 195P, 197L, 198P, 215V, 218F, 219M, 222F, 226P, 227L, 229W, 230A, 277A, 278S, 281Q, 282S, 285A, 286G, 289A, 301I, 302S, 305M, 306L, 312P, 418F, 421Y, 422Y, 425A, 426V, 429S, 443V, 447Y, 451G, 454L, 458S, 525G, 528M, 529T, 532F, 536T, 537T, 540T, 550L, 551V, 554A, 555S, 558R, 559N, 562A
CDD
cd06174 (MFS)

Protein sequence

>MCA_01690_1
MNSSSNNDEGFQENLGYLQNNNNNNNNNVTQFVTPSNTDNSSNQYHSPLNENFNNVPKNSASQILSTTPEKHFQIIEENI
PSQTDQKVYDLTEDKIIDKQDGTTSVSQAVSSSSSSSSSVEKIEIPINNDTIKQSTEQQATSQITEKQQQQQSTPPSPPP
KEPYTAFPIWRKRLILWLVTAAGFLGPLSGSIYLPILPTIRDEYEISTTAANASVSAFMAVFAVAPLIWASWADFGGRKM
LYMISLVIYIASCICLAALPSHAAVLFVFRVVQAFGASSVQSLGAGTVADIIEPKNRAAAISIFMLGPQLGPILGPILGG
AIASDNEWRWVFGFLAFVGAFVLLLIIVFLPETLRYFVGNGAIYGENQVVAKFTFRQKKIVEDSPKYPKPPKPSLKGYLR
LMRYIPVTLVSINAGLLFATYYGFAVTYSKYLKESYGFSTAEVGAAYIVPGISLVSGSLISGRLSDYLRKKAKAQHPDGK
VIPEQRLPVQIFGVIVSMVGILCYGWMLDKHVHVVSVMVFGFLAGFGMTWVFIVNTTYLTECSPGLPASLVAIASFFRNA
GAAISSVIIEPLIQKMGVGWCFTGLALIDLFGITMVIVLMMKGPTWREKLELKKAQAKQQPKSQPPITNEKK

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features