Protein

MIA_03127_1

Length
816 amino acids


Browser: contig04:300268-302810+

Protein function

EGGNOG:0PFEUCUL3SCF ubiquitin ligase subunit CulC
SGD closest match:S000002290CDC53Cell division control protein 53
CGD closest match:CAL0000197877CAALFM_CR00370WACullin

Protein alignments

%idAln lengthE-value
MCA_04958_169.240%8290.0MCA_04958_1
A0A0J9X2P4_GEOCN53.366%8170.0Similar to Saccharomyces cerevisiae YGR003W CUL3 Ubiquitin-protein ligase OS=Geotrichum candidum GN=BN980_GECA01s04597g PE=3 SV=1
UniRef50_A0A0J9X2P453.366%8170.0Similar to Saccharomyces cerevisiae YGR003W CUL3 Ubiquitin-protein ligase n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X2P4_GEOCN
A0A060T2Z0_BLAAD51.838%8160.0ARAD1C32780p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32780g PE=3 SV=1
A0A1E3PM44_9ASCO47.922%8180.0Ubiquitin-protein ligase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_41142 PE=3 SV=1
A0A167E8D1_9ASCO46.059%8880.0Cullin CUL3 OS=Sugiyamaella lignohabitans GN=CUL3 PE=3 SV=1
Q6CFU9_YARLI37.303%8230.0YALI0B03520p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B03520g PE=3 SV=1
A0A1E4TI86_9ASCO29.292%8339.01e-116Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_71415 PE=3 SV=1
A0A1D8PRP1_CANAL29.803%9162.54e-114Cullin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR00370WA PE=3 SV=1
CDC53_YEAST24.750%6991.56e-40Cell division control protein 53 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC53 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6456

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 700 816

Detailed signature matches

    1. SSF74788 (Cullin re...)
    1. PF00888 (Cullin)
    1. SSF75632 (Cullin ho...)
    2. PS50069 (CULLIN_2)
    3. SM00182 (cul_2)
    1. SSF46785 ("Winged h...)
    1. SM00884 (Cullin_Ned...)
    2. PF10557 (Cullin_Nedd8)
    1. PS01256 (CULLIN_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MIA_03127_1
MSRRARIRAPRKNLTVDADFESSWPILSAAIKEIHRKDASRLSFEELYRTAYTIVIRKNGKRLYEAVKAEVRAHLESELN
TRLLPKYKGAKLNKVDDGKSTSSATLTTTLASTEPNIELLTTTLGVWNDHCICMRMISDILMYLDRVYSREADVPLIYDA
GLSIFRDVIFNSVIEKEIYYAILGLLRKDRQGITADRPIIKSVVSMLEYLPDTALMGNSIYIGRFEPILFEDTEKYYQEA
ADNLLVANHNASIYISRTNSWIKDENQRCNMYLLPSSLSRLQLSVQRVLITDRFPKVLAFPENGFKHWIDTDQYQDIKLT
YELYQMVTSTFDVLKEILQAAVIERGMEINQRSIAALQAAKQARSGGHSNEKGKGKSDSQSPTAIAIQWVEMVLTLKEKF
DKIIKESLHQNSGINEAVDNSFAEFINKNNKVSEYLSLFIDDNLKKSLKGKTEMEIEDTLEKSIVLFRFIQDKDVFENYY
KAHLAKRLLNSKSLSDDIERSMIAKLKMEIGTSFTTRLEGMFKDMKISQEMMVEYKEEQDEEDEAAKRAKSETPGTPTPE
IKKNRVDISVNVLTSTFWPVSVVSSQIKCNYPEVIEQERARFEKFYLKRHTGRKLAWNSALGTADVKVRFAKRVHEINMP
TLAMIILLQFTEITDASGLTFEQLFEATNISKPDLVRHLQSLAVAPRTRILRKVPMSKDVKPSDKFFFNNKFESSMTRFK
VLAVSSSSKVETDSEKKETLAKVGQTRKYEVDAAIVRVMKTRKRLDHGMLVQDVISQLKQRFKADQTLIKSRIDNLLERE
YLERDPDERQFYNYLA

GO term prediction

Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process

Molecular Function

GO:0031625 ubiquitin protein ligase binding

Cellular Component

GO:0031461 cullin-RING ubiquitin ligase complex