Protein
MCA_04958_1
Length
814 amino acids
Gene name: CUL3
Description: Cullin-3; ubiquitin ligase subunit
Browser: contigC:4516649-4519156-
RNA-seq: read pairs 1691, FPKM 25.6, percentile rank 48.2% (100% = highest expression)
Protein function
| Annotation: | CUL3 | Cullin-3; ubiquitin ligase subunit | |
|---|---|---|---|
| KEGG: | K03869 | CUL3 | cullin 3 |
| EGGNOG: | 0PFEU | CUL3 | SCF ubiquitin ligase subunit CulC |
| SGD closest match: | S000003235 | CUL3 | Cullin-3 |
| CGD closest match: | CAL0000197877 | CAALFM_CR00370WA | Cullin |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03127_1 | 68.76% | 829 | 0.0 | MIA_03127_1 |
| A0A0J9X2P4_GEOCN | 54.36% | 815 | 0.0 | Similar to Saccharomyces cerevisiae YGR003W CUL3 Ubiquitin-protein ligase OS=Geotrichum candidum GN=BN980_GECA01s04597g PE=3 SV=1 |
| UniRef50_A0A0J9X2P4 | 54.36% | 815 | 0.0 | Similar to Saccharomyces cerevisiae YGR003W CUL3 Ubiquitin-protein ligase n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X2P4_GEOCN |
| A0A060T2Z0_BLAAD | 50.98% | 818 | 0.0 | ARAD1C32780p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32780g PE=3 SV=1 |
| A0A167E8D1_9ASCO | 48.40% | 876 | 0.0 | Cullin CUL3 OS=Sugiyamaella lignohabitans GN=CUL3 PE=3 SV=1 |
| A0A1E3PM44_9ASCO | 48.29% | 818 | 0.0 | Ubiquitin-protein ligase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_41142 PE=3 SV=1 |
| Q6CFU9_YARLI | 38.59% | 824 | 0.0 | YALI0B03520p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B03520g PE=3 SV=1 |
| A0A1E4TI86_9ASCO | 31.57% | 833 | 3e-130 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_71415 PE=3 SV=1 |
| A0A1D8PRP1_CANAL | 30.81% | 912 | 1e-125 | Cullin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR00370WA PE=3 SV=1 |
| CUL3_YEAST | 27.52% | 814 | 5e-60 | Cullin-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CUL3 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.4493
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Domain
-
Domain
-
Domain
1
100
200
300
400
500
600
700
814
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
mobidb-lite (disord...)
Protein sequence
>MCA_04958_1 MHRRARIRAPRKNLTMDGDFDTSWEILLRAIVEIHQKDASKLSFEELYRTAYTLVIRKHGRRLYESVKSEIRKHLGQVLI TQLIPKSKMKAKSKIKLPQNTTGPSEQPPTSLLPKESVEPNIELLTTMLSVWNDHCLCMRMISDILMYLDRVYSREAKVP LIYDAGLSIFRDVIFNSSIEGEIYITLLNILRKDRDGIPADRLLVKAIVKMLEFLPDASLLGPSIYCNRFEPHLFTDTEK YYDEAAENLLAGNHNASIYISITKSWLENEIERATMYLLPSSLERLKSGIERVLITNRFEKVLKFPENGFKHWVETDQYS DIHLAYQLYSLVTSQYEVFRDILKSLVIEKGSEINAHSKAALQAAKQARSQGSTKSKKQISGNSSLNVNNDSLSPTAIAI QWVEMVLKLRDKFDKIIIQSFDSHPVISADVDDSFSAFINKNAKVSEYLSLFIDDNLKKSLKGKSDSEIEDVLGKGVVLF RFIADKDIFESYYKAHLAKRLLNSKSLSDDIERSMIAKLKMEIGTSFTSKLEGMFRDMKISKEMMADYKEYRASNDPMIK GQTVDASVNVLTSTFWPVSVISSHIKCNYPPEIQSAKEEFERFYLARHTGRKLAWNPNLGTADVKVRFQKRVHEINMPTL AMIILLQFTELSDNNGLTFEQLLEQTNISAQDLTRHLQSLAVAPRTRILKKVPMSKDVKSTDKFFFNNKFESSMTRFKVL AISSNNKVETDTEKKETLAKVDQARKYQTDAAIVRVMKARKTLEHAILVDEVTKQLNSRFKPDPALIKNRIDHLLEQEYL ERDLEKRSVYNYLA
GO term prediction
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
Molecular Function
GO:0031625 ubiquitin protein ligase binding
Cellular Component
GO:0031461 cullin-RING ubiquitin ligase complex