Protein

MIA_03098_1

Length
706 amino acids

Browser: contig04:235867-237988+

Protein function

EGGNOG:0PFWADBP9ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs (By similarity)
SGD closest match:S000004266DBP9ATP-dependent RNA helicase DBP9
CGD closest match:CAL0000180288DBP9ATP-dependent RNA helicase DBP9

Protein alignments

%idAln lengthE-value
MCA_01584_167.374%6130.0MCA_01584_1
A0A0J9XAV6_GEOCN60.980%5920.0Similar to Saccharomyces cerevisiae YLR276C DBP9 ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 60S ribosomal subunit OS=Geotrichum candidum GN=BN980_GECA07s02716g PE=4 SV=1
A0A060TBG4_BLAAD54.530%5740.0ARAD1D27676p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D27676g PE=4 SV=1
A0A161HKA2_9ASCO54.746%5900.0Dbp9p OS=Sugiyamaella lignohabitans GN=DBP9 PE=4 SV=1
A0A1E3PQF4_9ASCO50.077%6510.0DEAD-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45621 PE=4 SV=1
UniRef50_Q6BLM551.689%5920.0ATP-dependent RNA helicase DBP9 n=28 Tax=saccharomyceta TaxID=716545 RepID=DBP9_DEBHA
DBP9_YEAST50.586%5970.0ATP-dependent RNA helicase DBP9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DBP9 PE=1 SV=1
DBP9_CANAL49.686%6360.0ATP-dependent RNA helicase DBP9 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DBP9 PE=3 SV=2
DBP9_YARLI48.217%5891.94e-174ATP-dependent RNA helicase DBP9 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=DBP9 PE=3 SV=1
A0A1E4TKN2_9ASCO44.613%5941.57e-161Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_84541 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8434

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 706

Detailed signature matches

  1. Domain IPR014014
    RNA helicase, DEAD-box type, Q motif
    1. PS51195 (Q_MOTIF)
  2. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  3. Domain IPR011545
    DEAD/DEAH box helicase domain
    1. PF00270 (DEAD)
  4. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  5. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd00079 (HELICc)
  4. mobidb-lite (disord...)

Residue annotation

  1. nucleotide binding...
  2. ATP-binding site c...

Protein sequence

>MIA_03098_1
MAKKKVSIKERIPKSALKKTPKAEETETTGLQDVDMEDIEKESSDEEEVEEDSQVQTEYDAYSEEEKKLLTMDEEALEDM
TFAELDLDSRLLQALSLIKLHKPTPIQVKAIPLALGLKKDIIGRAKTGSGKTVAYAIPIVESILQEAVKSQGEAGARKST
HKGAVGNRAIVLVPSRELADQVTKLFKSLTIFADKLVGVVNVSSQQSSSATATTSAENIMASLLATKPAIIVGTPAKVLA
HIQSGSIDASAISYLVIDEADLILSYGFREDLDALAQLLPVKKTIQTWLMSATISEDINDIKAAFCRKNLAVLRLEDTGA
EAGGASGNKLLQYYVKTAEIDKFLLTYVIFKLRLIRGKTLIFVNNIERCYQLKLFLEQFGIKSIVLNSELPIASRLHIVE
EFNRNVYDLLIATDENTHYMAEGDEEEEKEEEEGVKKRRGGKKSKFSSDKEYSVSRGVDFRNVACVLNFDLPTSATVYTH
RIGRTARANKSGMALSFVVPRKEWRKKENRAASLDTAKKDEKVLARVMKHQEKKRVKALKRLGLDEEQIASSSGIPEGYS
ESDAAVIIQPYVFDMKQMESFRYRMEGAFRAVTKMAVREARIKEIRQELLTSEKLKRHFEENPEDLVFLRHDKELHAAKV
QPHLKRVPQYLLPAQARSGLNTLQPAQHVGARKNNTNRVKKQQQQRKKKMSGAGRKGGDPLRSFRK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0005524 ATP binding

Cellular Component

None predicted.