Protein

MIA_03085_1

Length
670 amino acids

Browser: contig04:200811-202871-

Protein function

EGGNOG:0PH5UKAR2Glucose-regulated protein
SGD closest match:S000003571KAR278 kDa glucose-regulated protein homolog
CGD closest match:CAL0000199653KAR2Hsp70 family ATPase

Protein alignments

%idAln lengthE-value
MCA_00541_190.549%6560.0MCA_00541_1
A0A0J9XAK4_GEOCN84.259%6480.0Similar to Saccharomyces cerevisiae YJL034W KAR2 ATPase involved in protein import into the ER OS=Geotrichum candidum GN=BN980_GECA07s00527g PE=3 SV=1
A0A1E3PKT7_9ASCO78.495%6510.078 kDa glucose-regulated protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51211 PE=3 SV=1
A0A060T8H6_BLAAD79.563%6410.0ARAD1D06732p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D06732g PE=3 SV=1
GRP78_YARLI76.805%6510.078 kDa glucose-regulated protein homolog OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=KAR2 PE=3 SV=1
A0A167D4D5_9ASCO74.208%6630.0Hsp70 family ATPase KAR2 OS=Sugiyamaella lignohabitans GN=KAR2 PE=3 SV=1
UniRef50_A0A0G2E0Q174.057%6630.0Putative hsp70 chaperone n=4 Tax=Dikarya TaxID=451864 RepID=A0A0G2E0Q1_9EURO
GRP78_YEAST72.840%6480.078 kDa glucose-regulated protein homolog OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KAR2 PE=1 SV=1
A0A1D8PG96_CANAL72.171%6540.0Hsp70 family ATPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=KAR2 PE=3 SV=1
A0A1E4TB56_9ASCO73.190%6490.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_130416 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8144

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 670

Detailed signature matches

  1. Family IPR013126
    Heat shock protein 70 family
    1. PF00012 (HSP70)
    2. PR00301 (HEATSHOCK70)
  2. Domain IPR029047
    Heat shock protein 70kD, peptide-binding domain
    1. G3DSA:2.60.34.10
    2. SSF100920 (Heat sho...)
  3. Domain IPR029048
    Heat shock protein 70kD, C-terminal domain
    1. G3DSA:1.20.12...
    2. SSF100934 (Heat sho...)
  4. SITE IPR018181
    Heat shock protein 70, conserved site
    1. PS00297 (HSP70_1)
    2. PS01036 (HSP70_3)
    3. PS00329 (HSP70_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.42...
  2. NON_CYTOPLASM... (N...)
  3. SIGNAL_PEPTIDE (Sig...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. SSF53067 (Actin-lik...)
  8. SignalP-TM
  9. TMhelix
  10. cd10241 (HSPA5-like...)
  11. mobidb-lite (disord...)

Residue annotation

  1. nucleotide binding...
  2. putative NEF/HSP70...
  3. SBD interface cd10...

Protein sequence

>MIA_03085_1
MFSRSIRSMASWSAILVYIALILVFPFISGTSAEVDDKIQGPVIGIDLGTTYSCVGVMKSGRVEILANDQGNRITPSYVA
FNGEERLIGDAAKNQAAANPHNTIFDIKRLIGLYFKDSSVQKDIKRLPYKVIDRNGKPAVKVEFLNENKTFTPEEISAMI
LGQMKKIAEDYLGQDVKYAVITVPAYFNDAQRQATENAGEIAGLKVLRIVNEPTAAAIAYGLDKTDGERQIIVYDLGGGT
FDVSLLSIDKGFFQVLATAGDTHLGGEDFDYRVIRHFTKLFNKKHDVDISKNAKTIGKLKREVEKAKRTLSSQMSTRIEI
ESFFDGIDFSETLTRAKFEELNIDLFRKTLKPVEQVLKDAKVEKSEVDDIVLVGGSTRIPKVQELLETYFKGKKASKGIN
PDEAVAYGAAVQGGVLSGDDGAEDIVLLDVNPLTLGIETTGGVMTTLIKRNTVIPTRKSQIFSTAVDNQPTVLIQIYEGE
RPLSKDNNLLGKFELTGIPPSPRGVPKIEVTFELDANGMLKVTAHDKGTGKSESIVITNDKSRLSQDEIDQMIADAEKYA
EQDAALKEKIISRNGLENYAHSLKNQVNDEAGLGGKIDEDDKETILEAVSEVLEWLEEVGNDATKEDFDEKKEKLSSIAY
PITSKLYGDEGAGDSHPDDEDEDDYDHDEL

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.