Protein
MCA_00541_1
Length
670 amino acids
Gene name: KAR2
Description: protein of the HSP70 family, ATPase involved in protein import into the ER
Browser: contigA:1685839-1687928-
RNA-seq: read pairs 6465, FPKM 119.0, percentile rank 81.7% (100% = highest expression)
Protein function
| Annotation: | KAR2 | protein of the HSP70 family, ATPase involved in protein import into the ER | |
|---|---|---|---|
| KEGG: | K09490 | HSPA5 | heat shock 70kDa protein 5 |
| EGGNOG: | 0PH5U | KAR2 | Glucose-regulated protein |
| SGD closest match: | S000003571 | KAR2 | 78 kDa glucose-regulated protein homolog |
| CGD closest match: | CAL0000199653 | KAR2 | Hsp70 family ATPase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03085_1 | 90.77% | 650 | 0.0 | MIA_03085_1 |
| A0A0J9XAK4_GEOCN | 83.79% | 654 | 0.0 | Similar to Saccharomyces cerevisiae YJL034W KAR2 ATPase involved in protein import into the ER OS=Geotrichum candidum GN=BN980_GECA07s00527g PE=3 SV=1 |
| A0A1E3PKT7_9ASCO | 76.65% | 651 | 0.0 | 78 kDa glucose-regulated protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51211 PE=3 SV=1 |
| A0A060T8H6_BLAAD | 77.45% | 643 | 0.0 | ARAD1D06732p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D06732g PE=3 SV=1 |
| GRP78_YARLI | 75.46% | 648 | 0.0 | 78 kDa glucose-regulated protein homolog OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=KAR2 PE=3 SV=1 |
| A0A167D4D5_9ASCO | 73.36% | 657 | 0.0 | Hsp70 family ATPase KAR2 OS=Sugiyamaella lignohabitans GN=KAR2 PE=3 SV=1 |
| UniRef50_A0A093ZNV6 | 74.38% | 640 | 0.0 | Uncharacterized protein n=5 Tax=Pseudogymnoascus TaxID=78156 RepID=A0A093ZNV6_9PEZI |
| GRP78_YEAST | 72.53% | 648 | 0.0 | 78 kDa glucose-regulated protein homolog OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KAR2 PE=1 SV=1 |
| A0A1D8PG96_CANAL | 71.87% | 654 | 0.0 | Hsp70 family ATPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=KAR2 PE=3 SV=1 |
| A0A1E4TB56_9ASCO | 72.11% | 649 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_130416 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.4666
Protein family membership
- Heat shock protein 70 family (IPR013126)
Domains and repeats
-
Domain
-
Domain
1
100
200
300
400
500
600
670
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
NON_CYTOPLASM... (N...)
-
SIGNAL_PEPTIDE (Sig...)
-
SIGNAL_PEPTID... (S...)
-
SIGNAL_PEPTID... (S...)
-
SIGNAL_PEPTID... (S...)
-
SSF53067 (Actin-lik...)
-
-
-
cd10241 (HSPA5-like...)
-
mobidb-lite (disord...)
Residue annotation
-
nucleotide binding...
-
putative NEF/HSP70...
-
SBD interface cd10...
Protein sequence
>MCA_00541_1 MVKSFRSMASWSAVLLYISLIFLFPLIKTTSAEVEEKPHGPVIGIDLGTTYSCVGVMKAGKVEILANDQGNRITPSYVAF NGDERLIGDAAKNQAAGNPKNTIFDIKRLIGLYFKDTSVQKDIKRLPYTVIDRNGKPAVQVEYMNEKKTFTPEEISSMII GKMKQIAEDYLGQEVKYAVITVPAYFNDAQRQATENAGEIAGLKVLRIVNEPTAAAIAYGLDKTDGERQIIVYDLGGGTF DVSLLSIDKGFFQVLATAGDTHLGGEDFDYRVIRHFTKLFNKKHNVDITTNQKSIGKLKREVEKAKRTLSSQLSTRIEIE SFFDGIDFSETLTRAKFEELNLDLFRKTLKPVEQVLKDAKVDKSEVDDIVLVGGSTRIPKVQELLETYFKGKKASKGINP DEAVAYGAAVQGGVLAGDDGAEDIVLLDVNPLTLGIETTGGVMTTLIKRNTVIPTRKSQIFSTAVDNQPTVLIQIFEGER PLSKDNNLLGKFELTGIPPAPRGVPQIEVTFELDANGMLKVSATDKGTGKSESIVITNDKSRLSQDEIDKMIADAEKYAE QDKALKEKIVARNALENYAHTLKNQVNDDKGMGAKISEDDKETIVEAVNEVLEWLEEVGNDATKEDFEERKEKLSSIAYP ITSKLYGDSGAGGDDSHPDDEDSDYDHDEL
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.