Protein

MIA_02976_1

Length
689 amino acids


Browser: contig03:2234743-2236864+

Protein function

EGGNOG:0PHSNFG01789.1Ferric-chelate reductase
SGD closest match:S000005908FRE3Ferric reductase transmembrane component 3
CGD closest match:CAL0000185898CFL4Ferric/cupric-chelate reductase

Protein alignments

%idAln lengthE-value
MCA_05580_138.624%7121.83e-160MCA_05580_1
A0A0J9XI25_GEOCN37.080%6855.36e-147Similar to Saccharomyces cerevisiae YOR384W FRE5 Putative ferric reductase with similarity to Fre2p OS=Geotrichum candidum GN=BN980_GECA16s00164g PE=4 SV=1
UniRef50_A0A0J9XI2537.080%6851.10e-143Similar to Saccharomyces cerevisiae YOR384W FRE5 Putative ferric reductase with similarity to Fre2p n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XI25_GEOCN
Q6CF26_YARLI36.395%5882.82e-116YALI0B10846p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B10846g PE=4 SV=1
A0A167FY66_9ASCO31.025%6937.88e-103Fre2p OS=Sugiyamaella lignohabitans GN=FRE2 PE=4 SV=1
A0A060SVU5_BLAAD33.154%5589.85e-98ARAD1A00286p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A00286g PE=4 SV=1
A0A1E3PIN1_9ASCO28.757%6922.49e-90Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83263 PE=4 SV=1
A0A1D8PN54_CANAL28.732%7109.84e-82Ferric/cupric-chelate reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CFL4 PE=4 SV=1
A0A1E4TLJ4_9ASCO28.641%6185.93e-79Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30726 PE=4 SV=1
FRE3_YEAST26.567%6701.81e-61Ferric reductase transmembrane component 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FRE3 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0358
Predicted cleavage: 11

Protein family membership

None predicted.

Domains and repeats

1 100 200 300 400 500 600 689

Detailed signature matches

    1. PF01794 (Ferric_reduct)
    1. PS51384 (FAD_FR)
    1. PF08022 (FAD_binding_8)
    1. PF08030 (NAD_binding_6)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SFLDG01168 (Ferric_...)
  2. SFLDS00052 (Ferric_...)
  3. SSF52343 (Ferredoxi...)
  4. TRANSMEMBRANE (Tran...)
  5. cd06186 (NOX_Duox_l...)
  6. mobidb-lite (disord...)

Residue annotation

  1. FAD binding pocket...
  2. FAD binding motif ...
  3. beta-alpha-beta st...
  4. NAD pyrophosphate ...
  5. NAD binding pocket...
  6. NADP ribose bindin...

Protein sequence

>MIA_02976_1
MNKVGIGSRHPAFQLYEGCTALACTYMYSCPSKYSTSMGKTLNACDCQSDEFLATYVDCATRSGGDSTGAIKLLAKGCMA
LKSTKNVTTIMNAYQSQQNNFIEVSDIHNKSIQLTNAVYFSQTQIDNAYHSFRAIETNKYKSVLYGAALLCYFGGVFLIA
TLCNFTKSFAPGFAKRVSNTKPVLFIRQKIANPALGGFKHSLPYQWGPISMSPPSRSQFVILLGYTIMLFIFHFPNYDLF
DGNISFTTKYLQLTKYVADRTGIIAMAQLPLLYILASRNSIIMWCTGWNFDTMNMYHRWVARSMVLDSFLHAVLFSINYR
KRGSFFGHWKSYFMKWGVVAFICSCFILFFSLRFFRVSYYEFFLFSHWIFVCLFTAGTWKHLYGRGWTVWMFPCVALWAF
DRACRLGRIAFSSVTSTANLELSKNKEFVKVKIDYSFTWGPNAGNYAFLYFLLPFLKFWENHPFSCYPSPLPGEEQKLCF
VMKVQKGKTKQIANYLSRKDAGKVQVPVLIEGPYGHTFPVDKSDTIVLIAGGIGITATYSYATKLKKLSSKKHIILLWVT
RTHGNIEVMKDEINYLVSGSDSLDVSIYVTNEEASCSPFTEKNRSDESSSDEKKSDNKSEFENEIGVPISYGTPDLTSLI
VTYISQAPSSVGFFVCGPPVVNDVVRSAVTANMDKGKDRVDLFVEAFNW

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.