Protein

MIA_02940_1

Length
349 amino acids

Browser: contig03:2152856-2153970-

Protein function

EGGNOG:0PI11RPC40DNA-directed RNA polymerases I and III
SGD closest match:S000006314RPC40DNA-directed RNA polymerases I and III subunit RPAC1
CGD closest match:CAL0000195273RPC40DNA-directed RNA polymerase core subunit

Protein alignments

%idAln lengthE-value
MCA_03459_172.206%3490.0MCA_03459_1
A0A0J9X3U2_GEOCN62.678%3514.76e-154Similar to Saccharomyces cerevisiae YPR110C RPC40 RNA polymerase subunit AC40 OS=Geotrichum candidum GN=BN980_GECA02s00758g PE=4 SV=1
A0A060T300_BLAAD55.460%3485.01e-131ARAD1C36894p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C36894g PE=4 SV=1
A0A1E3PJ29_9ASCO51.312%3433.60e-119RBP11-like subunits of RNA polymerase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46935 PE=4 SV=1
A0A1D8PHD8_CANAL53.644%3431.01e-117DNA-directed RNA polymerase core subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RPC40 PE=4 SV=1
UniRef50_Q75A8752.395%3341.84e-113ADR031Cp n=11 Tax=Ascomycota TaxID=4890 RepID=Q75A87_ASHGO
RPAC1_YEAST52.836%3351.87e-115DNA-directed RNA polymerases I and III subunit RPAC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPC40 PE=1 SV=1
Q6C4T2_YARLI47.863%3511.73e-104YALI0E23947p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E23947g PE=4 SV=1
A0A1E4TL11_9ASCO49.211%3172.74e-102Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1035 PE=4 SV=1
A0A161HKL9_9ASCO53.737%2811.44e-98DNA-directed RNA polymerase core subunit RPC40 OS=Sugiyamaella lignohabitans GN=RPC40 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0523

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 349

Detailed signature matches

  1. Family IPR033901
    DNA-directed RNA polymerases I and III subunit AC40
    1. cd07032 (RNAP_I_II_...)
  2. Domain IPR009025
    DNA-directed RNA polymerase, RBP11-like dimerisation domain
    1. SSF55257 (RBP11-lik...)
  3. Domain IPR011263
    DNA-directed RNA polymerase, RpoA/D/Rpb3-type
    1. SM00662 (rpoldneu2)
    2. PF01193 (RNA_pol_L)
  4. Domain IPR011262
    DNA-directed RNA polymerase, insert domain
    1. PF01000 (RNA_pol_A_bac)
    2. SSF56553 (Insert su...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.13...

Residue annotation

  1. AC40 - AC19 hetero...
  2. AC40 - A135(C128) ...
  3. AC40 - RPB12 inter...
  4. AC40 - RPB10 inter...

Protein sequence

>MIA_02940_1
MSDDKIVGIKHDRVTNVTATDFPGHYNDVENAWSIETFKKQLDIKIHYLTDEVGNFDLVGADASVANAFRRIMMAEVPTV
AFEEVVFNNNTGIMHDEVLASRIGLVPLRIDPDKVEWYPFYEPAPVVDGETKSPANDRNTIPFTLKVACTHKAGAKNKAG
SGSSLKRADDLYEHHTVFAKDLVYAGSDEQLQKVFGGVRPEVLYPDIVLTKLRPGQEIDLVAYAVLGIGSDHAKFSPVAT
ASYRLMPHIELLEPIGGADAQKLQGVFSPGVIGIDDKGNAFVQDARRDTVSREVFRHEEFKDKVRLGRKRDHFIYHVEST
GAMQPDEIFVKSIDILRNKCLGLLQYDLA

GO term prediction

Biological Process

GO:0006351 transcription, DNA-templated

Molecular Function

GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0046983 protein dimerization activity

Cellular Component

None predicted.