Protein

MCA_03459_1

Length
349 amino acids

Gene name: RPC40

Description: DNA-directed RNA polymerases I and III subunit RPAC1

Browser: contigC:32962-34012+

RNA-seq: read pairs 2610, FPKM 92.1, percentile rank 77.3% (100% = highest expression)

Protein function

Annotation:RPC40DNA-directed RNA polymerases I and III subunit RPAC1
KEGG:K03027RPC40 DNA-directed RNA polymerases I and III subunit RPAC1
EGGNOG:0PI11RPC40DNA-directed RNA polymerases I and III
SGD closest match:S000006314RPC40DNA-directed RNA polymerases I and III subunit RPAC1
CGD closest match:CAL0000195273RPC40DNA-directed RNA polymerase core subunit

Protein alignments

%idAln lengthE-value
MIA_02940_172.21%3496e-180MIA_02940_1
A0A0J9X3U2_GEOCN62.90%3456e-147Similar to Saccharomyces cerevisiae YPR110C RPC40 RNA polymerase subunit AC40 OS=Geotrichum candidum GN=BN980_GECA02s00758g PE=4 SV=1
A0A060T300_BLAAD57.83%3512e-130ARAD1C36894p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C36894g PE=4 SV=1
A0A1E3PJ29_9ASCO54.65%3445e-123RBP11-like subunits of RNA polymerase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46935 PE=4 SV=1
A0A1D8PHD8_CANAL57.77%3414e-122DNA-directed RNA polymerase core subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RPC40 PE=4 SV=1
UniRef50_Q75A8756.60%3415e-118ADR031Cp n=11 Tax=Ascomycota TaxID=4890 RepID=Q75A87_ASHGO
RPAC1_YEAST56.76%3403e-121DNA-directed RNA polymerases I and III subunit RPAC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPC40 PE=1 SV=1
Q6C4T2_YARLI50.43%3512e-100YALI0E23947p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E23947g PE=4 SV=1
A0A1E4TL11_9ASCO50.48%3133e-99Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1035 PE=4 SV=1
A0A161HKL9_9ASCO56.20%2583e-93DNA-directed RNA polymerase core subunit RPC40 OS=Sugiyamaella lignohabitans GN=RPC40 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0084

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 349

Detailed signature matches

  1. Family IPR033901
    DNA-directed RNA polymerases I and III subunit AC40
    1. cd07032 (RNAP_I_II_...)
  2. Domain IPR009025
    DNA-directed RNA polymerase, RBP11-like dimerisation domain
    1. SSF55257 (RBP11-lik...)
  3. Domain IPR011263
    DNA-directed RNA polymerase, RpoA/D/Rpb3-type
    1. SM00662 (rpoldneu2)
    2. PF01193 (RNA_pol_L)
  4. Domain IPR011262
    DNA-directed RNA polymerase, insert domain
    1. PF01000 (RNA_pol_A_bac)
    2. SSF56553 (Insert su...)
  5. SITE IPR001514
    DNA-directed RNA polymerase, 30-40kDa subunit, conserved site
    1. PS00446 (RNA_POL_D_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.13...

Residue annotation

  1. AC40 - AC19 hetero...
  2. AC40 - A135(C128) ...
  3. AC40 - RPB12 inter...
  4. AC40 - RPB10 inter...

Protein sequence

>MCA_03459_1
MASLKTDNKIVGIEHDRVTNVTSTDFPGHYNTVSNEWSLDEFKKQLDINIQYLTDDVGNFDLIGVDSSIANAFRRIMMAE
VPSVAFEEVVVVNNTSVMHDEVLAHRIGLVPLKVDPDNLSWYPFHQEPKIVDGQVVSPSTIYNTVPFTLKVKCSHKPKPT
PGSTNPDDLYVNHKVYAKDLKYSGSKEQLEKVFSGVEPTVLNPDILLTKLRPGQEIELTAYAVLGIGSDHAKFSPVATAT
YRLMPHIEITSEEPITGESAKKLQSLFSPGVIGIDSKGAAFVKDPRKDTMSREIFRHEEFKDKVKLGRKRDHFIFHVEST
GAMQPDEIFVKSIDVLRNKCLQLLECNLD

GO term prediction

Biological Process

GO:0006351 transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0046983 protein dimerization activity

Cellular Component

None predicted.