Protein
MIA_02924_1
Length
604 amino acids
Browser: contig03:2095157-2097023+
Protein function
| EGGNOG: | 0PFP6 | FG09991.1 | glutamate-cysteine ligase |
|---|---|---|---|
| SGD closest match: | S000003637 | GSH1 | Glutamate--cysteine ligase |
| CGD closest match: | CAL0000193135 | GCS1 | Glutamate--cysteine ligase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_00849_1 | 65.469% | 640 | 0.0 | MCA_00849_1 |
| A0A0J9X6S6_GEOCN | 63.807% | 641 | 0.0 | Similar to Saccharomyces cerevisiae YJL101C GSH1 Gamma glutamylcysteine synthetase catalyzes the first step in glutathione (GSH) biosynthesis OS=Geotrichum candidum GN=BN980_GECA04s00351g PE=4 SV=1 |
| A0A060T4F1_BLAAD | 63.023% | 622 | 0.0 | ARAD1C40634p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C40634g PE=4 SV=1 |
| Q6C433_YARLI | 58.023% | 617 | 0.0 | YALI0E30129p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E30129g PE=4 SV=1 |
| A0A167EV99_9ASCO | 57.817% | 678 | 0.0 | Glutamate--cysteine ligase OS=Sugiyamaella lignohabitans GN=GSH1 PE=4 SV=1 |
| A0A1E4TIH1_9ASCO | 56.798% | 662 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29900 PE=4 SV=1 |
| A0A1E3PCG0_9ASCO | 57.488% | 621 | 0.0 | GCS-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53751 PE=4 SV=1 |
| UniRef50_A0A1E3PCG0 | 57.488% | 621 | 0.0 | GCS-domain-containing protein n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PCG0_9ASCO |
| GSH1_YEAST | 47.727% | 660 | 0.0 | Glutamate--cysteine ligase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GSH1 PE=1 SV=1 |
| A0A1D8PE63_CANAL | 45.783% | 581 | 7.47e-154 | Glutamate--cysteine ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GCS1 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0012
Protein family membership
- Glutamate-cysteine ligase catalytic subunit (IPR004308)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
SIGNAL_PEPTIDE (Sig...)
-
SIGNAL_PEPTID... (S...)
-
SIGNAL_PEPTID... (S...)
-
SIGNAL_PEPTID... (S...)
-
SSF55931 (Glutamine...)
-
TRANSMEMBRANE (Tran...)
Protein sequence
>MIA_02924_1 MGLLSLGTPLPWIEAQPLAQFVRDQGIEQLINIYNKCKDYHGQVLLWGDELEYMVVSLDPSARSARLSLRQAQILDTLAQ MEARSALGPVSYHPEYGRFMLEATPATPFTGAPADLLKVQPNMLLRRATARKILLPSEVPLTITSYPRLGVLNAPFTDPY YPPNGPAARSCFLPDEVINPHARFPTLTANIRTRRGSKVSINVPIFRDSNTPSPFVDAYPDDVPENYIHMDAMGFGMGCC CLQLTFQATNISEARTLYDQLAPLAPIMLALTAASPAYRGYLSDQDTRWNVISGAVDDRTPWERGLQPPPPGFSTDNSDV VIPKSRYDSIDSYLAQDPVLLADQAHYNDTKLVVNTRALARLSAAGLDPLLANHFAHLFIRDPIVIFRELLHQDNATSAD HFENIQSTNWQTLRFKPPPPGSDIGWRVEFRPMEVQTTDFENAAFSVFIVLLTRVILSYKLNLYMPISKVDENMRVAHHR DAVRSETFWFRKDVRRDSPKDYAKLSLDALVNGSDDFPGFIPLIRRYLAAASVDMDTLCELTKYLALVSKRASGALPTNA AWIRSFVTSHPDYHQDSVISETTNYDLMQELDRLTQAGTPPGGT
GO term prediction
Biological Process
GO:0006750 glutathione biosynthetic process
Molecular Function
GO:0004357 glutamate-cysteine ligase activity
Cellular Component
None predicted.