MIA_02917_1

Protein

Length

580 amino acids

Browser: contig03:2079741-2081484+

Protein function

EGGNOG:	0PFTW	FG04370.1	transporter
SGD closest match:	S000003951	TPO1	Polyamine transporter 1
CGD closest match:	CAL0000199735	FLU1	Flu1p

Protein alignments

	%id	Aln length	E-value
MCA_02420_1	53.152%	587	0.0	MCA_02420_1
A0A0J9X353_GEOCN	53.818%	537	0.0	Similar to Saccharomyces cerevisiae YLL028W TPO1 Polyamine transporter that recognizes spermine, putrescine,and spermidine OS=Geotrichum candidum GN=BN980_GECA01s01011g PE=4 SV=1
A0A1E3PPH0_9ASCO	51.434%	558	0.0	MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81829 PE=4 SV=1
Q6C2K7_YARLI	50.554%	542	6.02e-178	YALI0F07062p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F07062g PE=4 SV=1
A0A060T8V0_BLAAD	51.650%	515	2.27e-168	ARAD1C32472p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32472g PE=4 SV=1
A0A167CKS0_9ASCO	51.391%	539	3.88e-166	Tpo1p OS=Sugiyamaella lignohabitans GN=TPO1 PE=4 SV=1
UniRef50_A0A167CKS0	51.391%	539	1.07e-162	Tpo1p n=22 Tax=Saccharomycetales TaxID=4892 RepID=A0A167CKS0_9ASCO
G1UB37_CANAL	42.979%	584	7.48e-149	Flu1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=FLU1 PE=4 SV=1
A0A1E4TAB0_9ASCO	43.194%	551	6.42e-141	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_127309 PE=4 SV=1
TPO1_YEAST	45.714%	525	1.24e-136	Polyamine transporter 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPO1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0058

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
114 - 580
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 580

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  141 - 527
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  137 - 580
  
  PROSITE profiles
  PS50850 (MFS)
2. SSF103473 (MFS gene...)
  
  114 - 572
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
3. cd06174 (MFS)
  
  139 - 545
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

1 - 135

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

251 - 261

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

191 - 201

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

430 - 448

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

564 - 580

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

498 - 503

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

316 - 370

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

122 - 336

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

356 - 573

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

223 - 227

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

284 - 294

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

468 - 478

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

525 - 543

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

398 - 408

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

160 - 170

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

407 - 429

TMHMM
TMhelix (TMhelix)

478 - 500

TMHMM
TMhelix (TMhelix)

507 - 526

TMHMM
TMhelix (TMhelix)

541 - 563

TMHMM
TMhelix (TMhelix)

227 - 249

TMHMM
TMhelix (TMhelix)

202 - 221

TMHMM
TMhelix (TMhelix)

449 - 468

TMHMM
TMhelix (TMhelix)

136 - 158

TMHMM
TMhelix (TMhelix)

173 - 195

TMHMM
TMhelix (TMhelix)

365 - 387

TMHMM
TMhelix (TMhelix)

261 - 283

TMHMM
TMhelix (TMhelix)

293 - 315

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

202 - 222

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

295 - 315

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

544 - 563

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

262 - 283

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

479 - 497

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

409 - 429

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

371 - 397

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

136 - 159

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

449 - 467

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

504 - 524

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

228 - 250

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

171 - 190

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

Residue annotation

putative substrate...

152S

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

155F

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

156S

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

157P

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

159V

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

160S

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

177V

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

180Y

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

181V

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

184F

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

188P

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

189V

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

191W

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

192S

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

238G

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

239S

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

242L

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

243T

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

246A

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

247A

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

250A

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

265I

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

266D

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

269A

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

270M

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

276P

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

383Y

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

386L

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

387Y

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

390L

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

391S

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

394P

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

408A

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

413V

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

417T

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

420A

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

424A

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

489G

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

492L

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

493M

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

496L

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

500I

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

501N

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

504V

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

514A

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

515L

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

518L

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

519T

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

522R

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

523S

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

526G

putative substrate translocation pore
152S, 155F, 156S, 157P, 159V, 160S, 177V, 180Y, 181V, 184F, 188P, 189V, 191W, 192S, 238G, 239S, 242L, 243T, 246A, 247A, 250A, 265I, 266D, 269A, 270M, 276P, 383Y, 386L, 387Y, 390L, 391S, 394P, 408A, 413V, 417T, 420A, 424A, 489G, 492L, 493M, 496L, 500I, 501N, 504V, 514A, 515L, 518L, 519T, 522R, 523S, 526G
CDD
cd06174 (MFS)

Protein sequence

>MIA_02917_1
MTSVNVNEKVPANNDLEAGMETTHQKMVDVSPLNSIETGFDQQAPEPFYGSGRRESQADIRRRLSTISVYQTVEEQQTIA
NVLAQRNVDQSKPMPNMGGGRPFPPSLPDLDNYRVAFDGPDDPRHPFNWPSTRKTVIALILSLVTFTSAWGSSIFSPTVS
EISKLYHVRPVVASLGVSVYVMGFASGPVLWSPLSELYGRRLPVIISMLMFTCFSFACATAKDLQTIIITRFFTGMSGSS
PLTLVAAIFADMFSNQGRVTRGAAIDLFAMAVFAGPMISPIVGGFVVESYLGWRWTMYLTGILGALSLILVVLFVKETYA
PLILVDKAMDIRERTGNWGVHAVHEHVRIDLHEIMSNTIARPIKMLFSEPIILLIAIYNGFTYLILYLCLSSYPYAYVGK
YHWSLSMAMIPYVGILTGEAICCAVMILYFEPKYKKADKEGTATPEMRLAPVLPAAIAFPIGLFWFFWSSNYAQHCHWIV
PSLSGLFTGYGLMGILVPSINYIVDAYLFFAASALASLTLMRSMLGASSPLFATYMFNGIHLNWSGLLLGLVAVGLAPVP
FIFHKFGARIRGKSKYAFTE

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features