Protein

MCA_02420_1

Length
605 amino acids

Gene name: TPO1

Description: Polyamine transporter 1

Browser: contigB:1236061-1237879+

RNA-seq: read pairs 8904, FPKM 181.5, percentile rank 86.9% (100% = highest expression)

Protein function

Annotation:TPO1Polyamine transporter 1
KEGG:K08157TPO1 MFS transporter, DHA1 family, multidrug resistance protein
EGGNOG:0PFTWFG04370.1transporter
SGD closest match:S000003951TPO1Polyamine transporter 1
CGD closest match:CAL0000199735FLU1Flu1p

Protein alignments

%idAln lengthE-value
A0A0J9X353_GEOCN68.91%5340.0Similar to Saccharomyces cerevisiae YLL028W TPO1 Polyamine transporter that recognizes spermine, putrescine,and spermidine OS=Geotrichum candidum GN=BN980_GECA01s01011g PE=4 SV=1
A0A1E3PPH0_9ASCO59.31%5210.0MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81829 PE=4 SV=1
MIA_02917_153.48%5890.0MIA_02917_1
Q6C2K7_YARLI58.61%5050.0YALI0F07062p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F07062g PE=4 SV=1
A0A060T8V0_BLAAD57.78%5400.0ARAD1C32472p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32472g PE=4 SV=1
A0A167CKS0_9ASCO57.07%5520.0Tpo1p OS=Sugiyamaella lignohabitans GN=TPO1 PE=4 SV=1
UniRef50_A0A167CKS057.07%5520.0Tpo1p n=22 Tax=Saccharomycetales TaxID=4892 RepID=A0A167CKS0_9ASCO
A0A1E4TAB0_9ASCO49.91%5294e-170Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_127309 PE=4 SV=1
G1UB37_CANAL44.54%5952e-158Flu1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=FLU1 PE=4 SV=1
TPO1_YEAST52.10%5245e-157Polyamine transporter 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPO1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0334

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 605

Detailed signature matches

  1. Family IPR011701
    Major facilitator superfamily
    1. PF07690 (MFS_1)
  2. Domain IPR020846
    Major facilitator superfamily domain
    1. PS50850 (MFS)
    2. SSF103473 (MFS gene...)
    3. cd06174 (MFS)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:1.20.12...
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)
  6. mobidb-lite (disord...)

Residue annotation

  1. putative substrate...

Protein sequence

>MCA_02420_1
MSSFNEKSFGPSSNTDDIIPNSAPHNNRAESDTTSTEAALSSSINNNKTDLLKRNTSNDSNTSSNLSNEIPKPLNADDDL
EAGMDGRRLSHISTIQNIEEQDVITRILSGPPPHEGEPCPKMGGGRDYPPELPDMKLYQVDFDGPDDPLHPYNWPLSRKL
AIAVALGLCTLCVAWGSSIFSTATLALSEIFHVKPVVTILGMSLYVLGFASGPVIWSPLSEVYGRRMPLLLSMFIFTCLV
FGTATAKDLHTIMLCRFFSGFGGSAPLTVVAATFADMFDNNTRGIALDLFSGAVFAGPLLAPVVGGFIVESYLGWRWTLY
ITGILAGTSLTASALVMKETYTPVILIGKAREIREKTGNWGVFAAHEHVSLDLHSLVTNNLLRPMKILFTEPIVLLISIY
NSFIYGILYLFMEAYPIVFVEGYGMSSSVGMLPYIALVIGQLTACVVMIFVFEPKYVKAVQANKGLPLPEARLPGMMVGG
IVFPIGLLWFCWTGNYHETVHWMAPTASGLFTGFGLLTIFLPSINYIVDSYLFFAASALAGNTFLRSSFGAAFPLFAGYM
FHGMGTNYAGLLLGLVGLALAPVPFLFYKYGKRIRGHSKYAVVLE

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane