Protein

MIA_02875_1

Length
765 amino acids

Browser: contig03:1979455-1981966+

Protein function

EGGNOG:0PIRBMSH4DNA mismatch repair protein
SGD closest match:S000001891MSH4MutS protein homolog 4
CGD closest match:CAL0000197996CAALFM_CR01790CAMutS family protein

Protein alignments

%idAln lengthE-value
MCA_03499_152.099%8100.0MCA_03499_1
A0A0J9XHT0_GEOCN47.421%7950.0Similar to Saccharomyces cerevisiae YFL003C MSH4 Protein involved in meiotic recombination OS=Geotrichum candidum GN=BN980_GECA17s01539g PE=4 SV=1
UniRef50_A0A0J9XHT047.421%7950.0Similar to Saccharomyces cerevisiae YFL003C MSH4 Protein involved in meiotic recombination n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XHT0_GEOCN
MSH4_YEAST35.524%7155.21e-139MutS protein homolog 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSH4 PE=1 SV=2
A0A1D8PS25_CANAL32.287%6692.73e-91MutS family protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR01790CA PE=4 SV=1
A0A060TBS9_BLAAD23.234%7364.43e-30ARAD1B17798p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B17798g PE=3 SV=1
A0A167EK33_9ASCO33.469%2456.29e-28Mismatch repair protein MSH3 OS=Sugiyamaella lignohabitans GN=MSH3 PE=3 SV=1
A0A1E3PQS8_9ASCO30.081%2463.49e-26DNA mismatch repair protein msh-2 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_69419 PE=3 SV=1
A0A1E4TE51_9ASCO26.974%3041.67e-25Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31131 PE=3 SV=1
Q6C3F6_YARLI28.326%2332.66e-24YALI0F00154p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F00154g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4096
Predicted cleavage: 38

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 700 765

Detailed signature matches

  1. Family IPR011184
    DNA mismatch repair Msh2-type
    1. PIRSF005813 (MSH2)
  2. Domain IPR007860
    DNA mismatch repair protein MutS, connector domain
    1. G3DSA:3.30.42...
    2. SSF53150 (DNA repai...)
    3. PF05188 (MutS_II)
  3. Domain IPR007696
    DNA mismatch repair protein MutS, core
    1. SM00533 (DNAend)
    2. SSF48334 (DNA repai...)
    3. PF05192 (MutS_III)
  4. Domain IPR007861
    DNA mismatch repair protein MutS, clamp
    1. PF05190 (MutS_IV)
  5. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  6. Domain IPR000432
    DNA mismatch repair protein MutS, C-terminal
    1. PF00488 (MutS_V)
    2. SM00534 (mutATP5)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.14...
  2. G3DSA:3.40.50...

Protein sequence

>MIA_02875_1
MTSKPDSRQVSSYLHSMISEPTARSAVRSIGSGRAATAHLEESRAVSRSRAVSMGPSTDRVLCAVTEGRGVATVVGICFI
IPSTCELIMCNIVDSQTYIRTLQKLDVFDPDEILMPSSSILPVKSKLCELIETHFPAARIVETSRKHFNQDAERELVLDH
TFGPEREALGYEIADKYYMIGAASALLQNIKTKYAAIFDMNRLRIKIQASEDSMVLNTRTIKSLEIIHNSLEGASGMSLY
KLMNHTKTSMGARILRANLLQPLTRLENLTRRQNAVEELCCNVDIITECQQKLNVFEDMDKLLTAMSFQLKKKNTVTDRR
INQVIMLKDAVTTSIDIAEQVLVDVESELLVELREKLGGTQVREVKELISQYIEEDTRWAKSSQELRLQRTNAVKAGSNG
FLDISRTLFREYTDDFYATARKYVSEFGIPFEHGYDTKRGHFLKVPSHLAEEVEEKLDKDMFIHRRTTRRHIEMTTLDVM
KINIRIQNITKEIILMSDGIVDGLFEELAKRTFEMFLVSEAVAMLDLVCAFAHLATSSTGGYTRPEFTNEGVNREKLAVK
LSRHPILDRTVRFRPFVPNDIYASPDTSRMNIITGINMSGKSVYLRQIALLVIMAQVGSFIPAEFAKLPIYKGLYARIQS
EPGEDDMLASSFSAEMTEIAYILHHLGSSNMAAVAGAGEGAGSASEQLPDLVLIDELGRGSGVADGLAISLAITDWLVRV
PARRGGARQGVVTTFLSTHFQDLAKAMGARPGVALLNMRADVNMG

GO term prediction

Biological Process

GO:0006298 mismatch repair

Molecular Function

GO:0005524 ATP binding
GO:0030983 mismatched DNA binding

Cellular Component

None predicted.