Protein
MIA_02864_1
Length
505 amino acids
Browser: contig03:1952584-1954102-
Protein function
| EGGNOG: | 0PFPY | FG07019.1 | 3-hydroxyisobutyryl-CoA hydrolase |
|---|---|---|---|
| SGD closest match: | S000002443 | EHD3 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial |
| CGD closest match: | CAL0000174772 | EHD3 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_01644_1 | 50.916% | 491 | 2.49e-174 | MCA_01644_1 |
| A0A0J9X434_GEOCN | 51.250% | 480 | 1.45e-171 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Geotrichum candidum GN=BN980_GECA02s02331g PE=3 SV=1 |
| UniRef50_A0A0J9XIX1 | 50.000% | 464 | 8.51e-154 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XIX1_GEOCN |
| A0A060SXR4_BLAAD | 44.898% | 490 | 1.16e-150 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A11396g PE=3 SV=1 |
| A0A167EH75_9ASCO | 45.455% | 484 | 1.50e-149 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Sugiyamaella lignohabitans GN=EHD3 PE=3 SV=1 |
| A0A1E3PJK4_9ASCO | 45.111% | 450 | 5.77e-140 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46814 PE=3 SV=1 |
| A0A1E4TAJ0_9ASCO | 46.187% | 459 | 3.46e-134 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3410 PE=3 SV=1 |
| Q6CA37_YARLI | 42.324% | 482 | 1.25e-129 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D06215g PE=3 SV=1 |
| Q5AI24_CANAL | 37.472% | 451 | 7.19e-87 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=EHD3 PE=3 SV=1 |
| HIBCH_YEAST | 33.264% | 481 | 2.52e-74 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EHD3 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.8056
Predicted cleavage: 20
Protein family membership
- Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type (IPR032259)
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
400
450
505
Detailed signature matches
no IPR
Unintegrated signatures
-
-
cd06558 (crotonase-...)
Residue annotation
-
substrate binding ...
-
oxyanion hole (OAH...
-
trimer interface c...
Protein sequence
>MIA_02864_1 MIQIRTLPVRQFKPSTYLTQIRAYNKMALKAKINSSMLPELNIPNPPTYSKFAPAYDPNDMLASSKRGVYTITLNRPSKL NCIDQSMIDKIIPQLREWVGEKAAQVVIIKGSGNRALSAGGDVAALAKDNYYNGQEGSARSTIYFRDEYYLNHLLATYRK PVISIMNGITMGGGVGISVHAPFRIITEKTLFAMPEADIGFFPDVGGTYFLPRLDGQTGIYLGLTSKRLKGYDAYVAGVG THFISESLLPEVEARLEEVFSHRAASTHDAYELVNSVLMEFESPPPEGYQFFLTGKARKMIDECFSLETAEEIVAALQAD GSELALEARKNMLARSPTSVKVTLAAMRRARRLGIRQALEAELRLAENFMYGKEFVEGVKAKLISKPPRAPQWNPPTLEE VSDKLVQQYLSNRPNTVVEDNKFFHPEHNGLYPRHHYGLPAERHVKEYISGTRFGRKTRVSAQEVMDFFIHETQSKAGVH EKIQDILDRKTKPHPLNKNLLEWVY
GO term prediction
Biological Process
GO:0008152 metabolic process
Molecular Function
GO:0003824 catalytic activity
GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity
Cellular Component
None predicted.