Protein

MIA_02854_1

Length
732 amino acids

Browser: contig03:1929064-1931263-

Protein function

EGGNOG:0PGHSPRT1Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (By similarity)
SGD closest match:S000005888PRT1Eukaryotic translation initiation factor 3 subunit B
CGD closest match:CAL0000183631PRT1Eukaryotic translation initiation factor 3 subunit B

Protein alignments

%idAln lengthE-value
MCA_00569_162.014%6950.0MCA_00569_1
A0A0J9XBQ9_GEOCN57.615%6960.0Eukaryotic translation initiation factor 3 subunit B OS=Geotrichum candidum GN=PRT1 PE=3 SV=1
A0A167C0N2_9ASCO46.583%7170.0Eukaryotic translation initiation factor 3 subunit B OS=Sugiyamaella lignohabitans GN=PRT1 PE=3 SV=1
UniRef50_A0A167C0N246.583%7170.0Eukaryotic translation initiation factor 3 subunit B n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167C0N2_9ASCO
A0A060T6M9_BLAAD46.562%6980.0Eukaryotic translation initiation factor 3 subunit B OS=Blastobotrys adeninivorans GN=PRT1 PE=3 SV=1
EIF3B_YARLI45.468%6950.0Eukaryotic translation initiation factor 3 subunit B OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PRT1 PE=3 SV=1
A0A1E3PN29_9ASCO44.702%6890.0Eukaryotic translation initiation factor 3 subunit B OS=Nadsonia fulvescens var. elongata DSM 6958 GN=PRT1 PE=3 SV=1
EIF3B_CANAL40.704%7101.02e-166Eukaryotic translation initiation factor 3 subunit B OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRT1 PE=3 SV=1
A0A1E4TD39_9ASCO38.750%7202.58e-151Eukaryotic translation initiation factor 3 subunit B OS=Tortispora caseinolytica NRRL Y-17796 GN=PRT1 PE=3 SV=1
EIF3B_YEAST36.245%6876.34e-131Eukaryotic translation initiation factor 3 subunit B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRT1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1247

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 732

Detailed signature matches

  1. Family IPR011400
    Eukaryotic translation initiation factor 3 subunit B
    1. PIRSF036424 (Transl...)
    2. MF_03001 (eIF3b)
  2. Domain IPR000504
    RNA recognition motif domain
    1. SSF54928 (RNA-bindi...)
    2. PS50102 (RRM)
    3. SM00360 (rrm1_1)
    4. PF00076 (RRM_1)
  3. Domain IPR034363
    eIF3B, RNA recognition motif
    1. cd12278 (RRM_eIF3B)
  4. Domain IPR015943
    WD40/YVTN repeat-like-containing domain
    1. G3DSA:2.130.1...
  5. Domain IPR013979
    Translation initiation factor, beta propellor-like domain
    1. PF08662 (eIF2A)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.70...
  2. SSF82171 (DPP6 N-te...)

Residue annotation

  1. dimer interface cd...
  2. polypeptide substr...

Protein sequence

>MIA_02854_1
MAAERIASRDDDDLHLDYTDLERKYAVKDFGLENFIVVDNIPAKVPESKLPKLSKVLGKLFGEAGPIKADGLNLPLEGGA
TAGYAFVEYETPEAAANAIKILNGKRLDAKHMFVVNKLSDIERYATDSSITDTYAEPKKTDFKPREHLRSWLTDSAGRDQ
LFIHVKDSINVFWYKKTEPPKMAGKIERVDLPAKWSPKGTYLATSYSFGIQLNGGPSFGTLSQFFHFNATYFDFSPNERY
LITFSNVPIGDSRENDPENPDTPFSEKDRGNQIVIWDILTQLPLRSFRHYPNETSGTWPIFKWSSDSKYFARIVSDQLAI
YETPSMSLLDKKSVSIPGIVDFSFAPTSIVLKGRNILAGAPVDPNRKGDQVLCYWTPEIGNQAARVSIMTVPSKEVIRTR
NLFSVADCRFHWQDEGKYLCVKVDRYTRNKKQTFTNLEFFRMTERDIPLENIELKDTVVNFAWEPKGNKFITISRTDNSV
SSQLDGALASTSGLNNLSFYGLDEKKKVTSSSWKLLKLFEKRNTNSIFWSPKGQFAATSNFGPNVNTPLVEFWDTDFHAE
KREGVVDNSNGINNIGSYEQYGLVNLEWDPSGRFVAVWSNKTQSSNYKIINFFGEEITDKNLDHLRVVSWRPRPRSLLTE
EEKAKIIKNLNKYSVQFDEEDAMDADAATKELITKRRAQFKQWKEFRERAVAKLRSLGIAPEEDLVKEGAADGELIEETV
EEIIEETQEIVE

GO term prediction

Biological Process

GO:0006413 translational initiation

Molecular Function

GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0031369 translation initiation factor binding

Cellular Component

GO:0005852 eukaryotic translation initiation factor 3 complex