Protein

MIA_02821_1

Length
589 amino acids

Browser: contig03:1849876-1851646-

Protein function

EGGNOG:0PHV2FG01333.1prolyl-tRNA synthetase
SGD closest match:S000000889AIM10Probable proline--tRNA ligase, mitochondrial
CGD closest match:CAL0000194318PRSPutative proline--tRNA ligase

Protein alignments

%idAln lengthE-value
MCA_02566_154.077%6010.0MCA_02566_1
A0A0J9X809_GEOCN56.343%5360.0Similar to Saccharomyces cerevisiae YER087W AIM10 Protein with similarity to tRNA synthetases OS=Geotrichum candidum GN=BN980_GECA05s00505g PE=4 SV=1
UniRef50_A0A0J9X80956.343%5360.0Similar to Saccharomyces cerevisiae YER087W AIM10 Protein with similarity to tRNA synthetases n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X809_GEOCN
A0A060SWL7_BLAAD46.630%5491.03e-155ARAD1A02244p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A02244g PE=4 SV=1
A0A1E4TCI9_9ASCO43.281%5066.08e-141Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17015 PE=4 SV=1
A0A167CTJ1_9ASCO41.873%5663.42e-133Putative proline--tRNA ligase AIM10 OS=Sugiyamaella lignohabitans GN=AIM10 PE=4 SV=1
A0A1D8PRZ3_CANAL39.539%5212.18e-123Putative proline--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRS PE=4 SV=1
A0A1E3PGM6_9ASCO39.815%5401.45e-121Prolyl-tRNA synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52221 PE=4 SV=1
SYPM_YEAST35.363%5093.17e-100Probable proline--tRNA ligase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AIM10 PE=1 SV=1
Q6C8Z3_YARLI49.554%2243.19e-56YALI0D15620p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D15620g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9108
Predicted cleavage: 20

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 589

Detailed signature matches

  1. Family IPR002316
    Proline-tRNA ligase, class IIa
    1. PR01046 (TRNASYNTHPRO)
  2. Domain IPR006195
    Aminoacyl-tRNA synthetase, class II
    1. PS50862 (AA_TRNA_LI...)
  3. Domain IPR002314
    Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)
    1. PF00587 (tRNA-synt_2b)
  4. Domain IPR004154
    Anticodon-binding
    1. SSF52954 (Class II ...)
    2. G3DSA:3.40.50...
    3. PF03129 (HGTP_antic...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.93...
  2. SSF55681 (Class II ...)

Protein sequence

>MIA_02821_1
MIRSALAKRPPIFALARRQHSSAVSPASALDAYKIQASVPRLSLHLLPGEQESAEDPLVRYGYVRQVSAGSYHLLPLAHM
VQTNIADLARRHMVSVGGVEVSLSSLSSPALWERTGRAANTELFKIKHEDGASGENELARVQYILAPTHEEEITNLVATN
IAASRRKLPLRLFQITRKYRNEKRPRGGLLRGREFLMKDMYSFDVTQEDAHRTYEEVAAAYRAFFESVDVPFVVAEADSG
SIGGSLSHEYHYLSPVGEDNVVTCHTCKYTANVEKALAFPPEKDDGAFLGEAAVQYFLSNDKTTLVAAYYPPDREFSPLH
LLAELPEDTVNAEAESTGIEVAEEFAAQARADDDEGLFTRRLIRVMDARLSRETNLPELPFRANKGTTTTMVDVPLVMAQ
TGDLCPSCDDGETPLVVGKAVEIGHTFYLGTKYSTPLNATARDPVSGSLVPIEMGCYGIGISRLLPAIASVTADADGLSW
PASIAPYHAIVVSKNLDAATAIVQELRAAGVNAVWDDREDVSFGAAMRDARALGFPVTLVAGKQYQKTGLVELQPRNLSV
QQLKEKRGDPAFQSSVKDLPARVKELLKL

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006433 prolyl-tRNA aminoacylation

Molecular Function

GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004827 proline-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm