Protein

MCA_02566_1

Length
642 amino acids

Gene name: AIM10

Description: Probable proline--tRNA ligase, mitochondrial

Browser: contigB:1668184-1670113-

RNA-seq: read pairs 1358, FPKM 26.1, percentile rank 48.8% (100% = highest expression)

Protein function

Annotation:AIM10Probable proline--tRNA ligase, mitochondrial
KEGG:K01881PARS prolyl-tRNA synthetase [EC:6.1.1.15]
EGGNOG:0PHV2FG01333.1prolyl-tRNA synthetase
SGD closest match:S000000889AIM10Probable proline--tRNA ligase, mitochondrial
CGD closest match:CAL0000194318PRSPutative proline--tRNA ligase

Protein alignments

%idAln lengthE-value
MIA_02821_155.56%5760.0MIA_02821_1
A0A0J9X809_GEOCN51.69%5630.0Similar to Saccharomyces cerevisiae YER087W AIM10 Protein with similarity to tRNA synthetases OS=Geotrichum candidum GN=BN980_GECA05s00505g PE=4 SV=1
UniRef50_A0A0J9X80951.69%5630.0Similar to Saccharomyces cerevisiae YER087W AIM10 Protein with similarity to tRNA synthetases n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X809_GEOCN
A0A060SWL7_BLAAD46.17%5482e-158ARAD1A02244p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A02244g PE=4 SV=1
A0A1E4TCI9_9ASCO43.98%5232e-150Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17015 PE=4 SV=1
A0A167CTJ1_9ASCO40.70%5756e-132Putative proline--tRNA ligase AIM10 OS=Sugiyamaella lignohabitans GN=AIM10 PE=4 SV=1
A0A1E3PGM6_9ASCO39.86%5572e-128Prolyl-tRNA synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52221 PE=4 SV=1
A0A1D8PRZ3_CANAL39.89%5543e-123Putative proline--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRS PE=4 SV=1
SYPM_YEAST33.39%5542e-101Probable proline--tRNA ligase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AIM10 PE=1 SV=1
Q6C8Z3_YARLI49.80%2451e-70YALI0D15620p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D15620g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9950
Predicted cleavage: 47

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 642

Detailed signature matches

  1. Family IPR002316
    Proline-tRNA ligase, class IIa
    1. PR01046 (TRNASYNTHPRO)
  2. Domain IPR006195
    Aminoacyl-tRNA synthetase, class II
    1. PS50862 (AA_TRNA_LI...)
  3. Domain IPR002314
    Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)
    1. PF00587 (tRNA-synt_2b)
  4. Domain IPR004154
    Anticodon-binding
    1. SSF52954 (Class II ...)
    2. G3DSA:3.40.50...
    3. PF03129 (HGTP_antic...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.93...
  2. SSF55681 (Class II ...)

Protein sequence

>MCA_02566_1
MRSLLSIQKRLVFKSPVSRSFLVSVNQSFPFSKSQLYYVPNHFTRNHATQSCTSRSDNDYKIITTVPKLSQLLIPVLSND
NPSEDILVKHGYIKQVSSGIYHLLPLGQMVLRNIETIIRKYMVAVGGAELALSTFSNPKLWEQTGRINNAELFQLNDESA
AVDSSSQTNSKPNWILAPTHEEEITALVASSISSSYRKLPLRLFQITRKYRKEKRPRGGLLRGKEFLMKDMYSFDATKEE
ALQAYEDFQWAYNKIFSELKVPFVVAEADTGSIGGTLSHEYHYLADIGEDEVATCTECKYTANVEKAVARPPETEEEIVN
KEDIEKAKEQPEAKVEYYLSDDKETLVAAYYPASRVFNPLHLALELPEDVLPSDLETCVKGESALETFVSNAKENNDPEL
LMRRVIRVMDSRINKFTPLPEFPFKLNRSTTTTLVDVPIVMAQNGDLCPSCESPSLKVSKAIEVGHTFYLGTKYSEPLKA
LIYPQTDSKGKSTQLVPIEMGCYGIGVSRVLASIAYINSDVDGLSWPANIAPYHAVIVSKDPKNVGAKIVSSLREEGGIN
AVLDDTFTESKGFGLALRNARSLGFPATIVVGNNFEKTGKVEIQPRNMTVAELKKARLEGKSHHLEATLEELPSKLKKLL
EI

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006433 prolyl-tRNA aminoacylation

Molecular Function

GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004827 proline-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm