Protein

MIA_02802_1

Length
431 amino acids


Browser: contig03:1793318-1794614-

Protein function

EGGNOG:0PFWYERG24)-reductase
SGD closest match:S000005224ERG24Delta(14)-sterol reductase
CGD closest match:CAL0000185086ERG24Delta(14)-sterol reductase

Protein alignments

%idAln lengthE-value
MCA_01435_174.478%4310.0MCA_01435_1
A0A0J9XGH8_GEOCN65.596%4360.0Similar to Saccharomyces cerevisiae YNL280C ERG24 C-14 sterol reductase, acts in ergosterol biosynthesis OS=Geotrichum candidum GN=BN980_GECA15s00538g PE=4 SV=1
A0A060T633_BLAAD63.466%4270.0ARAD1C16918p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C16918g PE=4 SV=1
A0A1E3PD45_9ASCO53.241%4324.35e-146ERG4/ERG24 ergosterol biosynthesis protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_28983 PE=4 SV=1
Q6CDK2_YARLI52.093%4304.19e-141YALI0B23298p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B23298g PE=4 SV=1
UniRef50_Q6CDK252.093%4309.71e-138YALI0B23298p n=4 Tax=Saccharomycetales TaxID=4892 RepID=Q6CDK2_YARLI
ERG24_YEAST45.516%4462.37e-118Delta(14)-sterol reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG24 PE=1 SV=1
A0A1D8PIC7_CANAL45.434%4491.01e-111Delta(14)-sterol reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ERG24 PE=4 SV=1
A0A1E4TMI1_9ASCO40.674%4452.07e-99Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_95800 PE=4 SV=1
A0A167EQY0_9ASCO31.403%4494.75e-35Delta(24(24(1)))-sterol reductase OS=Sugiyamaella lignohabitans GN=ERG4 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0677

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. PF01222 (ERG4_ERG24)
    1. PS01018 (STEROL_RED...)
    2. PS01017 (STEROL_RED...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)

Protein sequence

>MIA_02802_1
MPKPNRKLNPLTTEPDFNGWPGALAISIGLPLLFNIFCFTCNDLGCPVSWTSLEPYRAQLASRALFSWHALGVYAAWWSF
LSILDRIVPGETVEGTLLRDGKTRLKYVFNGKLVMVILFSLLAARAVTTHGALPELVYVYDHLTELMNASLLVAVVGSTI
LYLAPLYLYREEPILALGGNTGNPIFDWFIGRELNPRIGNFDLKLFNEMRPGLLLWVIINLAMMHHQWLKYGAVSDSMWL
VVLFESYYVIEGTFYERGLINMIDTTTDGLGFMLLFGDLTLVPFSYTMQARYLADHPVHLGFWGVLGCVSVFAVGLLIFR
LSNNEKNAFRNNDPSTAHLKYITSKTGSKLLVSGWWGAARHINYFGDWLVAWAYCLPTGFGSILPYYFVFFFAGLLIHRN
ERDEAKCAEKYGETWVEYKRRVPYKFIPWVY

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

Cellular Component

GO:0016020 membrane