Protein
MCA_01435_1
Length
430 amino acids
Gene name: ERG24
Description: Delta(14)-sterol reductase
Browser: contigA:4446407-4447700+
RNA-seq: read pairs 3083, FPKM 88.4, percentile rank 76.9% (100% = highest expression)
Protein function
| Annotation: | ERG24 | Delta(14)-sterol reductase | |
|---|---|---|---|
| KEGG: | K00222 | TM7SF2 | Delta14-sterol reductase [EC:1.3.1.70] |
| EGGNOG: | 0PFWY | ERG24 | )-reductase |
| SGD closest match: | S000005224 | ERG24 | Delta(14)-sterol reductase |
| CGD closest match: | CAL0000185086 | ERG24 | Delta(14)-sterol reductase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02802_1 | 74.48% | 431 | 0.0 | MIA_02802_1 |
| A0A0J9XGH8_GEOCN | 63.68% | 435 | 0.0 | Similar to Saccharomyces cerevisiae YNL280C ERG24 C-14 sterol reductase, acts in ergosterol biosynthesis OS=Geotrichum candidum GN=BN980_GECA15s00538g PE=4 SV=1 |
| A0A060T633_BLAAD | 62.21% | 426 | 0.0 | ARAD1C16918p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C16918g PE=4 SV=1 |
| A0A1E3PD45_9ASCO | 52.90% | 431 | 4e-156 | ERG4/ERG24 ergosterol biosynthesis protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_28983 PE=4 SV=1 |
| Q6CDK2_YARLI | 49.65% | 433 | 5e-145 | YALI0B23298p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B23298g PE=4 SV=1 |
| UniRef50_Q6CDK2 | 49.65% | 433 | 1e-141 | YALI0B23298p n=4 Tax=Saccharomycetales TaxID=4892 RepID=Q6CDK2_YARLI |
| ERG24_YEAST | 47.17% | 441 | 1e-130 | Delta(14)-sterol reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG24 PE=1 SV=1 |
| A0A1D8PIC7_CANAL | 46.58% | 453 | 3e-125 | Delta(14)-sterol reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ERG24 PE=4 SV=1 |
| A0A1E4TMI1_9ASCO | 40.45% | 445 | 3e-111 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_95800 PE=4 SV=1 |
| A0A167EQY0_9ASCO | 28.70% | 446 | 1e-38 | Delta(24(24(1)))-sterol reductase OS=Sugiyamaella lignohabitans GN=ERG4 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0519
Protein family membership
- Ergosterol biosynthesis ERG4/ERG24 (IPR001171)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
Protein sequence
>MCA_01435_1 MPKPNRKLNPVTKNPDFGGVPGALLISIGLPLLCNVLYFTCNEKGCPASWTSLEPIYTQLKEKPLISLDAFLVYIAWVAA LIFLDRVVPGVEAYGVTLRDGTKLKYKFNGKAVMVILFSLLSARFVITYGRLPELVFVYENLLQLLNSSLLIAIVGSIVL YICPFLFYKEEPILALGGNTGNHIFDWFIGRELNPRIGDFDLKVFAEMRPGLLLWVIINLSMMHHQWLKYGKVTDSMWLV VLFQCHYVVEGTFYESGLINMIDVTTDGFGFMLIFGDLTLVPFTYTLQARYLADHPLELGLWKSLGCIAVFLVGLLIFRL SNNEKNAFRNGDPKTKHLKYIQSKTGSKLLISGWWGTARHINYLGDWVVAWAYCLPTGFNTIITYYFVFFFGGLLINRND RDEEKCAEKYGETWIEYKKHVPYKFIPYIY
GO term prediction
Biological Process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
Cellular Component
GO:0016020 membrane