Protein

MIA_02787_1

Length
352 amino acids

Browser: contig03:1767274-1768434+

Protein function

EGGNOG:0PFNJPMK1Mitogen-activated protein kinase
SGD closest match:S000000112FUS3Mitogen-activated protein kinase FUS3
CGD closest match:CAL0000176774CEK1Extracellular signal-regulated kinase 1

Protein alignments

%idAln lengthE-value
MCA_03098_188.636%3520.0MCA_03098_1
A0A0J9X3K3_GEOCN86.167%3470.0Mitogen-activated protein kinase OS=Geotrichum candidum GN=BN980_GECA01s10548g PE=3 SV=1
A0A060T4U5_BLAAD78.286%3500.0Mitogen-activated protein kinase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C44286g PE=3 SV=1
A0A167CH86_9ASCO79.710%3450.0Mitogen-activated protein kinase OS=Sugiyamaella lignohabitans GN=FUS3 PE=3 SV=1
Q6C4V0_YARLI77.810%3470.0Mitogen-activated protein kinase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E23496g PE=3 SV=1
UniRef50_A0A1S9RNS880.466%3430.0Mitogen-activated protein kinase n=2 Tax=Penicillium brasilianum TaxID=104259 RepID=A0A1S9RNS8_9EURO
A0A1E3PKB9_9ASCO79.009%3430.0Mitogen-activated protein kinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83382 PE=3 SV=1
A0A1E4TGJ3_9ASCO73.121%3460.0Mitogen-activated protein kinase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26393 PE=3 SV=1
ERK1_CANAL72.727%3630.0Extracellular signal-regulated kinase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CEK1 PE=1 SV=3
FUS3_YEAST60.571%3501.03e-161Mitogen-activated protein kinase FUS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FUS3 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0389

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 352

Detailed signature matches

  1. Family IPR008352
    Mitogen-activated protein (MAP) kinase, p38
    1. PR01773 (P38MAPKINASE)
  2. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  3. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
  4. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  5. SITE IPR003527
    Mitogen-activated protein (MAP) kinase, conserved site
    1. PS01351 (MAPK)
  6. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:3.30.20...
  3. PIRSF000654 (ILK)
  4. cd07849 (STKc_ERK1_...)

Residue annotation

  1. ATP binding site c...
  2. active site cd07849
  3. polypeptide substr...
  4. KIM docking site c...
  5. activation loop (A...

Protein sequence

>MIA_02787_1
MNIHHGEPRKISFHVSDQYQIKDVVGEGAYGIVCSAVHKETGLQVAIKKITPFDRTMFCLRTLREIKLLRHFSHENIISI
VDIQKPISYDQFTDVYLIQELMETDMHRVIRTQTLSDDHCQYFIYQTFRALKALHSANVLHRDLKPSNLLLNSNCDLKIC
DFGLARSAASSDDNSGFMTEYVATRWYRAPEIMLTFKEYTKAIDMWSVGCILAEMLTGKPLFPGKDYHNQLTLIIEILGT
PVMEDYYNIKSRRARDYIRSLQFTRKRSFAELFPRANPLAIDLLEKLLTFNPTKRLTVEDALEHPYLASYHDPDDEPTAP
PIPEEFFDFDKQKDQLGTKELKQLIYNEIMKY

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004707 MAP kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.