Protein

MCA_03098_1

Length
352 amino acids

Gene name: FUS3

Description: Mitogen-activated serine/threonine protein kinase; in S. cerevisiae involved in mating

Browser: contigB:3367257-3368426+

RNA-seq: read pairs 1387, FPKM 48.5, percentile rank 64.8% (100% = highest expression)

Protein function

Annotation:FUS3Mitogen-activated serine/threonine protein kinase; in S. cerevisiae involved in mating
KEGG:K04371MAPK1_3 mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
EGGNOG:0PFNJPMK1Mitogen-activated protein kinase
SGD closest match:S000000112FUS3Mitogen-activated protein kinase FUS3
CGD closest match:CAL0000176774CEK1Extracellular signal-regulated kinase 1

Protein alignments

%idAln lengthE-value
A0A0J9X3K3_GEOCN91.07%3470.0Mitogen-activated protein kinase OS=Geotrichum candidum GN=BN980_GECA01s10548g PE=3 SV=1
MIA_02787_188.64%3520.0MIA_02787_1
A0A060T4U5_BLAAD81.74%3450.0Mitogen-activated protein kinase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C44286g PE=3 SV=1
Q6C4V0_YARLI81.56%3470.0Mitogen-activated protein kinase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E23496g PE=3 SV=1
A0A167CH86_9ASCO81.16%3450.0Mitogen-activated protein kinase OS=Sugiyamaella lignohabitans GN=FUS3 PE=3 SV=1
A0A1E3PKB9_9ASCO80.47%3430.0Mitogen-activated protein kinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83382 PE=3 SV=1
UniRef50_A6R6J280.29%3500.0Mitogen-activated protein kinase n=17 Tax=Dikarya TaxID=451864 RepID=A6R6J2_AJECN
A0A1E4TGJ3_9ASCO76.01%3460.0Mitogen-activated protein kinase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26393 PE=3 SV=1
ERK1_CANAL74.10%3630.0Extracellular signal-regulated kinase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CEK1 PE=1 SV=3
FUS3_YEAST60.29%3503e-158Mitogen-activated protein kinase FUS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FUS3 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1008

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 352

Detailed signature matches

  1. Family IPR008352
    Mitogen-activated protein (MAP) kinase, p38
    1. PR01773 (P38MAPKINASE)
  2. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  3. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
  4. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  5. SITE IPR003527
    Mitogen-activated protein (MAP) kinase, conserved site
    1. PS01351 (MAPK)
  6. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:3.30.20...
  3. PIRSF000654 (ILK)
  4. cd07849 (STKc_ERK1_...)

Residue annotation

  1. ATP binding site c...
  2. active site cd07849
  3. polypeptide substr...
  4. KIM docking site c...
  5. activation loop (A...

Protein sequence

>MCA_03098_1
MSVHHGEPRKISFNVSDQYQIKDVVGEGAYGIVCSAVHKPTNLKVAIKKITPFERTMFCLRTLREIKLLRHFSHENIISI
VDIQKPISYELFNEVYLIQELMETDMHRVIRTQTLSDDHCQYFIYQTFRALKALHSANVLHRDLKPSNLLLNSNCDLKIC
DFGLARSAASSDDNFGFMTEYVATRWYRAPEIMLTFKEYTKAIDMWSVGCILAEMLTGKPLFPGRDYHNQLTLILDVLGT
PTMEDYYNVKSRRAREYLRSLPFTRRRNFTQLFAGANPLAIDLLEKLLTFNPAKRISVEQALEHPYLKPYHDADDEPTAP
PIPEEFFDFDKRKDEMGTAELKKLIYDEIMKY

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004707 MAP kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.