MIA_02765_1

Protein

Length

1,011 amino acids

Protein function

EGGNOG:	0PFQ8	PGUG_05311	cell cycle protein kinase
SGD closest match:	S000002175	CDC7	Cell division control protein 7
CGD closest match:	CAL0000191207	CDC7	Serine/threonine protein kinase

Protein alignments

	%id	Aln length	E-value
MCA_03717_1	59.829%	234	5.25e-85	MCA_03717_1
A0A0J9X5C3_GEOCN	47.059%	221	1.30e-58	Similar to Saccharomyces cerevisiae YDL017W CDC7 DDK (Dbf4-dependent kinase) catalytic subunit OS=Geotrichum candidum GN=BN980_GECA03s00296g PE=4 SV=1
UniRef50_A0A0J9X5C3	47.059%	221	2.65e-55	Similar to Saccharomyces cerevisiae YDL017W CDC7 DDK (Dbf4-dependent kinase) catalytic subunit n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X5C3_GEOCN
A0A167CGD1_9ASCO	42.291%	227	2.93e-53	Serine/threonine protein kinase CDC7 OS=Sugiyamaella lignohabitans GN=CDC7 PE=4 SV=1
A0A060TBK4_BLAAD	40.167%	239	4.77e-47	ARAD1D32560p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D32560g PE=4 SV=1
A0A1E3PS09_9ASCO	42.222%	225	7.66e-49	Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_54681 PE=4 SV=1
Q6C0N0_YARLI	40.758%	211	1.01e-39	YALI0F23287p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F23287g PE=4 SV=1
CDC7_YEAST	40.826%	218	8.12e-40	Cell division control protein 7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC7 PE=1 SV=2
A0A1D8PHD2_CANAL	42.365%	203	4.14e-37	Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC7 PE=4 SV=1
A0A1E4TLZ5_9ASCO	37.755%	98	4.87e-12	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_92635 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6642
Predicted cleavage: 20

Protein family membership

None predicted.

Domains and repeats

Domain
313 - 820
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 100 200 300 400 500 600 700 800 900 1011

Detailed signature matches

IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  393 - 517
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
  
  620 - 725
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
  
  785 - 820
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
  
  313 - 347
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. PS50011 (PROTEIN_KI...)
  
  328 - 812
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
2. SM00220 (serkin_6)
  
  328 - 812
  
  SMART
  SM00220 (serkin_6)
3. PF00069 (Pkinase)
  
  623 - 812
  
  Pfam
  PF00069 (Pkinase)
  
  397 - 519
  
  Pfam
  PF00069 (Pkinase)
IPR008271

Serine/threonine-protein kinase, active site
1. PS00108 (PROTEIN_KI...)
  
  485 - 497
  
  PROSITE patterns
  PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

G3DSA:1.10.51...

466 - 818

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.30.20...

148 - 465

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
cd14019 (STKc_Cdc7)

327 - 687

CDD
cd14019 (STKc_Cdc7)
mobidb-lite (disord...)

1 - 27

MobiDB Lite
mobidb-lite (disorder_prediction)

42 - 61

MobiDB Lite
mobidb-lite (disorder_prediction)

231 - 293

MobiDB Lite
mobidb-lite (disorder_prediction)

142 - 167

MobiDB Lite
mobidb-lite (disorder_prediction)

919 - 1,011

MobiDB Lite
mobidb-lite (disorder_prediction)

602 - 626

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

334V

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

335G

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

336E

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

337G

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

340S

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

342V

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

400A

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

402K

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

430L

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

446I

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

447P

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

448Y

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

449F

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

451H

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

493Q

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

494N

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

496L

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)

508D

ATP binding site
334V, 335G, 336E, 337G, 340S, 342V, 400A, 402K, 430L, 446I, 447P, 448Y, 449F, 451H, 493Q, 494N, 496L, 508D
CDD
cd14019 (STKc_Cdc7)
active site cd14019

334V

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

335G

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

336E

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

337G

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

338A

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

342V

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

400A

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

402K

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

412R

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

430L

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

446I

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

447P

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

448Y

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

449F

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

453D

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

455R

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

456E

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

489D

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

491K

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

493Q

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

494N

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

496L

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

508D

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

511L

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

624Y

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

626R

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

627A

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

628G

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

629T

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

631G

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

670A

active site
334V, 335G, 336E, 337G, 338A, 342V, 400A, 402K, 412R, 430L, 446I, 447P, 448Y, 449F, 453D, 455R, 456E, 489D, 491K, 493Q, 494N, 496L, 508D, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)
polypeptide substr...

412R

polypeptide substrate binding site
412R, 455R, 489D, 491K, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

455R

polypeptide substrate binding site
412R, 455R, 489D, 491K, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

489D

polypeptide substrate binding site
412R, 455R, 489D, 491K, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

491K

polypeptide substrate binding site
412R, 455R, 489D, 491K, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

511L

polypeptide substrate binding site
412R, 455R, 489D, 491K, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

624Y

polypeptide substrate binding site
412R, 455R, 489D, 491K, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

626R

polypeptide substrate binding site
412R, 455R, 489D, 491K, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

627A

polypeptide substrate binding site
412R, 455R, 489D, 491K, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

628G

polypeptide substrate binding site
412R, 455R, 489D, 491K, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

629T

polypeptide substrate binding site
412R, 455R, 489D, 491K, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

631G

polypeptide substrate binding site
412R, 455R, 489D, 491K, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)

670A

polypeptide substrate binding site
412R, 455R, 489D, 491K, 511L, 624Y, 626R, 627A, 628G, 629T, 631G, 670A
CDD
cd14019 (STKc_Cdc7)
activation loop (A...

507V

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

508D

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

509F

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

510G

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

511L

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

512A

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

513E

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

514P

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

515G

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

516P

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

618Q

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

619R

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

620P

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

621A

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

622R

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

623R

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

624Y

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

625N

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

626R

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

627A

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

628G

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

629T

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

630R

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

631G

activation loop (A-loop)
507V, 508D, 509F, 510G, 511L, 512A, 513E, 514P, 515G, 516P, 618Q, 619R, 620P, 621A, 622R, 623R, 624Y, 625N, 626R, 627A, 628G, 629T, 630R, 631G
CDD
cd14019 (STKc_Cdc7)

Protein sequence

>MIA_02765_1
MSFTQNRQKPQSFRIQSRPTVTVNPSQTPADVFTEPSTKISSFRSSQGMNHRCSNDTEATTSQKNLKYNGRPIKIARKTR
HIEDDIEEVDAEYHSPSLKRISPNEENLNGSTLTNTNLARTKLLSTPKKNTIDKVHDISLIDANTPTQNPNTNEPEDKET
KTIKKKRKYSETNELFVALFRGDNASSSSSNNSTALQDSQALLTSNHADLFPKIEGPQDSIIEKKTSPIINQPATQPINS
SQPTPPSKTNLAETEIKENNLLDKSQPKSPCAATKSSPQLLSKKQSQPNNLADEQPDVYVFLEKAGDQENKEEIQSLYRS
LPVLKGNYLVIKKVGEGAFSSVYKAIDLKHGKFKNFWDNGYAESVYLKQRIQDRTKFRETALECYKKHKLPPIAPFKYVA
IKRIHVTAHPRRISVELSLLAKLAGSPNLLPLITAFRHEDQVAAIIPYFEHNDFREYYDRLTLSEIKVYFKQLFNALAFI
HDQNIIHRDVKSQNFLYNLKTHRGVLVDFGLAEPGPNPKKLKCDCRNGGIASQYPDLDPLHRHSHFNTSTSTSSSLSTST
RSFHNTYQYSRGLSMSSASSIAAAATAAASAAAAASAANAKSGTAPFTTQGGKPKNDQRPARRYNRAGTRGFRAPEVLFG
CPDQNTSIDIWSAGIMLLAFLTKRCMFFQAKDDSRALIEMATIFGRRKMQTCALLHGVVYETNIQTIPEEGYPLSSLIYW
CLAAHYHEISRRNKAYGKTVEFTCEFTDEKVPKKKKKEDSDKAGSKSKAMVSSYIGPLSAETLKAIEFLQLCLELDFRKR
ITATQALSHPFLKNTHLDIPIFGCPDEMEGVDEQTDNFGDVLYYGVDPSDSEPYLAGEEDAIEQALGQLEANYLKNLNSK
ADVSLPEDPDIIDISAIHRKAQDINNCDVTEDTVFGLNPKLGIPGNHQNACQTEGKDKEYEKEDSEGGDKDDGEDDEKES
FEEQKRVMGDVEPEQEKATSISYANDSGMYLENPSSLSRQPKQYRQSNLGS

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component