MCA_03717_1

Protein

Length

1,311 amino acids

Gene name: CDC7

Description: Cell division control protein 7; in S. cerevisiae required for origin firing and replication fork progression in mitotic S phase

Browser: contigC:861609-865545+

RNA-seq: read pairs 719, FPKM 6.8, percentile rank 20.2% (100% = highest expression)

Protein function

Annotation:		CDC7	Cell division control protein 7; in S. cerevisiae required for origin firing and replication fork progression in mitotic S phase
KEGG:	K02214	CDC7	cell division control protein 7 [EC:2.7.11.1]
EGGNOG:	0PFQ8	PGUG_05311	cell cycle protein kinase
SGD closest match:	S000002175	CDC7	Cell division control protein 7
CGD closest match:	CAL0000191207	CDC7	Serine/threonine protein kinase

Protein alignments

	%id	Aln length	E-value
A0A0J9X5C3_GEOCN	45.81%	382	4e-107	Similar to Saccharomyces cerevisiae YDL017W CDC7 DDK (Dbf4-dependent kinase) catalytic subunit OS=Geotrichum candidum GN=BN980_GECA03s00296g PE=4 SV=1
UniRef50_A0A0J9X5C3	45.81%	382	8e-104	Similar to Saccharomyces cerevisiae YDL017W CDC7 DDK (Dbf4-dependent kinase) catalytic subunit n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X5C3_GEOCN
A0A060TBK4_BLAAD	44.44%	378	8e-97	ARAD1D32560p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D32560g PE=4 SV=1
A0A167CGD1_9ASCO	43.65%	362	4e-96	Serine/threonine protein kinase CDC7 OS=Sugiyamaella lignohabitans GN=CDC7 PE=4 SV=1
A0A1E3PS09_9ASCO	48.19%	359	3e-97	Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_54681 PE=4 SV=1
MIA_02765_1	60.43%	230	2e-84	MIA_02765_1
Q6C0N0_YARLI	40.49%	368	4e-75	YALI0F23287p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F23287g PE=4 SV=1
CDC7_YEAST	37.33%	225	3e-37	Cell division control protein 7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC7 PE=1 SV=2
A0A1D8PHD2_CANAL	38.24%	204	6e-33	Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC7 PE=4 SV=1
A0A1E4TLZ5_9ASCO	27.01%	211	4e-17	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_92635 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0563

Protein family membership

None predicted.

Domains and repeats

Domain
764 - 1,267
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 200 400 600 800 1000 1200 1311

Detailed signature matches

IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  1,234 - 1,267
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
  
  861 - 985
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
  
  1,030 - 1,134
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
  
  764 - 807
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. PS50011 (PROTEIN_KI...)
  
  788 - 1,261
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
2. PF00069 (Pkinase)
  
  845 - 1,137
  
  Pfam
  PF00069 (Pkinase)
3. SM00220 (serkin_6)
  
  788 - 1,261
  
  SMART
  SM00220 (serkin_6)
IPR008271

Serine/threonine-protein kinase, active site
1. PS00108 (PROTEIN_KI...)
  
  953 - 965
  
  PROSITE patterns
  PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

G3DSA:1.10.51...

1,217 - 1,284

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)

932 - 1,216

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.30.20...

612 - 931

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
cd14019 (STKc_Cdc7)

788 - 1,097

CDD
cd14019 (STKc_Cdc7)
mobidb-lite (disord...)

142 - 205

MobiDB Lite
mobidb-lite (disorder_prediction)

623 - 665

MobiDB Lite
mobidb-lite (disorder_prediction)

1,159 - 1,207

MobiDB Lite
mobidb-lite (disorder_prediction)

501 - 533

MobiDB Lite
mobidb-lite (disorder_prediction)

348 - 403

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 45

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

794V

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

795G

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

796E

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

797G

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

800S

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

802V

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

868A

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

870K

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

898L

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

914M

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

915P

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

916Y

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

917F

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

919H

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

961Q

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

962N

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

964L

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)

976D

ATP binding site
794V, 795G, 796E, 797G, 800S, 802V, 868A, 870K, 898L, 914M, 915P, 916Y, 917F, 919H, 961Q, 962N, 964L, 976D
CDD
cd14019 (STKc_Cdc7)
active site cd14019

794V

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

795G

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

796E

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

797G

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

798A

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

802V

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

868A

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

870K

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

880R

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

898L

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

914M

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

915P

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

916Y

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

917F

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

921D

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

923R

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

924D

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

957D

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

959K

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

961Q

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

962N

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

964L

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

976D

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

979L

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

1,034F

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

1,036R

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

1,037A

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

1,038G

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

1,039T

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

1,041G

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

1,080A

active site
794V, 795G, 796E, 797G, 798A, 802V, 868A, 870K, 880R, 898L, 914M, 915P, 916Y, 917F, 921D, 923R, 924D, 957D, 959K, 961Q, 962N, 964L, 976D, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)
polypeptide substr...

880R

polypeptide substrate binding site
880R, 923R, 957D, 959K, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

923R

polypeptide substrate binding site
880R, 923R, 957D, 959K, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

957D

polypeptide substrate binding site
880R, 923R, 957D, 959K, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

959K

polypeptide substrate binding site
880R, 923R, 957D, 959K, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

979L

polypeptide substrate binding site
880R, 923R, 957D, 959K, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

1,034F

polypeptide substrate binding site
880R, 923R, 957D, 959K, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

1,036R

polypeptide substrate binding site
880R, 923R, 957D, 959K, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

1,037A

polypeptide substrate binding site
880R, 923R, 957D, 959K, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

1,038G

polypeptide substrate binding site
880R, 923R, 957D, 959K, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

1,039T

polypeptide substrate binding site
880R, 923R, 957D, 959K, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

1,041G

polypeptide substrate binding site
880R, 923R, 957D, 959K, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)

1,080A

polypeptide substrate binding site
880R, 923R, 957D, 959K, 979L, 1,034F, 1,036R, 1,037A, 1,038G, 1,039T, 1,041G, 1,080A
CDD
cd14019 (STKc_Cdc7)
activation loop (A...

975V

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

976D

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

977F

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

978G

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

979L

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

980A

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

981E

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

982S

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

983A

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

984P

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

985E

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

1,029R

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

1,030P

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

1,031A

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

1,032R

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

1,033R

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

1,034F

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

1,035N

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

1,036R

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

1,037A

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

1,038G

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

1,039T

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

1,040R

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

1,041G

activation loop (A-loop)
975V, 976D, 977F, 978G, 979L, 980A, 981E, 982S, 983A, 984P, 985E, 1,029R, 1,030P, 1,031A, 1,032R, 1,033R, 1,034F, 1,035N, 1,036R, 1,037A, 1,038G, 1,039T, 1,040R, 1,041G
CDD
cd14019 (STKc_Cdc7)

Protein sequence

>MCA_03717_1
MSNSNQQSTWNFNSSGSNKNNNNNSNNNSTINPPHSFSNHNSLPYQQIKHQPNGLEFNQIDSINAYSNNYSRLASRIPQN
SLPNNNRASTNFNDYYPQPSVTNLTNTGKPCDTSLLILPSPPSPNSQQQASTLQPLNNNFNQSQVYYSLPPPIPSGSINQ
ANTSFNLSPNPQHQNLSNSQSPRMSNSRLVNNNIHNQNNRLTPTNPTFYHSLGNNGGNHSTNSSSGDHNAWNAAQQQRPN
NNMAIHSTNDITNSISYGPEGNSQFQSPGKHQTLYNQPHMHKILNNSVNFHYSAPNPISNPNLNMPMVNPVNTGYELTEL
DSFYQTPPVEAIYMPEFHNKVFEHQSQHYHTPSAYSPKQPSQLQYSNTTTPKTNNADLNNTTNTNASNYPSLSQAQSQSY
PTPCQVTNETNYRFPSITSTSIGNNASNESTQITDRNNTLQPLSNQVSQPIHNHQSAMQIDFSKFQTNSLDLIKDSTRIF
STQNPQSKNIQNRILNSPNCASYANSPYNEPQLSMNSTQRDDDIKQEETPSENFVETFSQPSVNTISNIKTHDLRNNFTS
PLHGYPNLNTQIPRAENSSHLTNPTARLTQHFRPSIEGLNSNRNSPAEINERQAYKVSEYEHSQFRQSTNSYTNNSRPNT
IHVTSANSNVDGNSVSKNNASPVQSNPEIMKTFEQNIPLQNKQNIPLQNKQNMSLQNKQNTEANSDSIATDKIAITQNQD
GLGKNGQAGINNSNHALKRKEADTPSKSNIYDTHNKVALPEPTSFDYPDSQAEINDFYRNYVTIKDSYTLIAKVGEGAFS
TVFKAIDKNYNLYDNPWDNGYSQSVYFKYREEERSRIRNLVKDAVAKQKESKTGEDFVSKVIPPKYVAIKRIHVTTHPRR
ISLEITLLTKLTGSPNLLPLITADRYQDQVIVVMPYFEHHDFRDFYDTLSLQEIRVYFKQLFNALAFIHEKKIIHRDVKN
QNFLYNLKTHRGVLVDFGLAESAPETNSKLKCDCRYGGLLSKSKYASSSNSKLSFGIPFQGGKYKRDSRPARRFNRAGTR
GFRAPEVLFCCTDQTTKIDVWSAGIMLLSFLTKKCMFFQAKDDSRAIIEMATIFGKRKMKACALLHGAAYETNIPTISEH
GYQFEQLIKWCLDAHYNEIMLADSAKRRRKEVRERQMIKYQEDQHVDQVNMENPESLTNKNSHSSSQDTETDNSSKNQSS
AESAEKLQQAAPVSYTFDTYTLGCSQLPSDTLKAIDFLKNCLELDYRRRYTATQALNHPFLKNVRLDIPIHGEKTRSNPN
CRDFPSYYYDGEVYPAEYRDPCSYYLNQMIK

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component