Protein

MIA_02744_1

Length
871 amino acids

Browser: contig03:1629578-1632904-

Protein function

EGGNOG:0PF9JMSH5mismatch repair protein
SGD closest match:S000002313MSH5MutS protein homolog 5

Protein alignments

%idAln lengthE-value
MCA_03177_146.545%8250.0MCA_03177_1
A0A0J9X3W8_GEOCN41.809%7630.0Similar to Saccharomyces cerevisiae YDL154W MSH5 Protein of the MutS family OS=Geotrichum candidum GN=BN980_GECA02s01396g PE=4 SV=1
UniRef50_A0A0J9X3W841.809%7630.0Similar to Saccharomyces cerevisiae YDL154W MSH5 Protein of the MutS family n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X3W8_GEOCN
A0A1D8PLP6_CANAL34.335%6326.06e-82MutS family protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_C402820WA PE=4 SV=1
MSH5_YEAST30.675%6522.84e-75MutS protein homolog 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSH5 PE=1 SV=1
A0A167DRY8_9ASCO25.556%5401.60e-36Mismatch repair ATPase MSH6 OS=Sugiyamaella lignohabitans GN=MSH6 PE=3 SV=1
Q6C0A2_YARLI27.190%5488.51e-36YALI0F26499p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F26499g PE=3 SV=1
A0A060TI93_BLAAD26.571%5577.55e-35ARAD1D37092p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D37092g PE=3 SV=1
A0A1E3PGX6_9ASCO25.176%5685.44e-35Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52294 PE=3 SV=1
A0A1E4TCE1_9ASCO25.000%6002.20e-33Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_15349 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0391

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 871

Detailed signature matches

  1. Family IPR017261
    DNA mismatch repair protein MutS/MSH
    1. PIRSF037677 (Msh6)
  2. Domain IPR007696
    DNA mismatch repair protein MutS, core
    1. SM00533 (DNAend)
    2. SSF48334 (DNA repai...)
    3. PF05192 (MutS_III)
  3. Domain IPR007861
    DNA mismatch repair protein MutS, clamp
    1. PF05190 (MutS_IV)
  4. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  5. Domain IPR000432
    DNA mismatch repair protein MutS, C-terminal
    1. PF00488 (MutS_V)
    2. SM00534 (mutATP5)
    3. PS00486 (DNA_MISMAT...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. G3DSA:1.10.14...
  4. G3DSA:3.40.50...
  5. NON_CYTOPLASM... (N...)
  6. TRANSMEMBRANE (Tran...)

Protein sequence

>MIA_02744_1
MDSSTSFIEQNNSNLTVSDQYTDVTDVSAESVTLAEVIKPQVILAIDCKGTKVGCAVYRKDSKWMSCYVDCTIQACDPVE
EFSVIFKQWKETIIPTNLLVSPSFPLEFEPVINDKNDVTEYKIDYRPSHEFSVSAAIKNLSNAFTQNASVFQPDYEQAVA
HSKFWVHQMNPESSDIDLNPFSNSFFDEDNKLSVIQTSAAGCMSSIFSFLAFEGDMDVEKCIKRFTIDSLRCLFNLRENN
MVISTETITALRLFQDASHPNLHYTKPTQITSSTCLFKIINQTCSQLGAELLKEWIFKPSTNMNVIKTRHDLIEIFLLSE
HDDILKSMRKSLRKIKNVPRIIRDMELISLPLSDWNALVSFLTEYRELLELASRTPQIYETPLFLSIAKALSRELLQDLL
NQITSVINMEKSELMGEIEIQPEINTKLDELKENYANLDTILESITQELEEKLQLFGIFSVSYIAQIGFLISVDGKHMTK
VRNMISAENVDNWEEVFSTSTTYYYKSQTMQYMNQTLGDIYGVIADMTVEITQKLQSVISEQSTNLSKACRVIAQLDCHL
SLAWAARQNGYKRPVMTSGRDLIIKEGYHPLYAKLVETFISNGVSLRYDEEGGDSRSNLLLVTGANFSGKTVYLTQTAVI
VVMAQIGSFVPASEARIGIVDRILTRVSSRESVSKSKSSFLSDLEQMSSIFRVMTPRSLLIVDEFGKGTDTKDGAALFGS
MINYMQSLENKAPKLIASTHFHELLEQDIIREEGGLNVCYMEIFIDENAGNRGISYLYKTHPGKTSSSFGICCAKMCGID
PDIISLAEKIYEEKVRGGNFATFFLNCSPEEELRLKQAGRIVRKFLEEDLDKTKSMWEFLSTLLAPIKGLP

GO term prediction

Biological Process

GO:0006298 mismatch repair

Molecular Function

GO:0005524 ATP binding
GO:0030983 mismatched DNA binding

Cellular Component

None predicted.