Protein

MIA_02727_1

Length
393 amino acids

Browser: contig03:1560324-1561831-

Protein function

EGGNOG:0PHHEURE2glutathione s-transferase
SGD closest match:S000005173URE2Transcriptional regulator URE2
CGD closest match:CAL0000198677URE2Protein URE2

Protein alignments

%idAln lengthE-value
MCA_01505_179.856%2781.53e-168MCA_01505_1
A0A060SYG7_BLAAD80.000%2551.54e-161Protein URE2 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A12210g PE=3 SV=1
A0A0J9X904_GEOCN81.349%2521.19e-157Protein URE2 OS=Geotrichum candidum GN=BN980_GECA05s04619g PE=3 SV=1
A0A167E427_9ASCO79.283%2513.48e-156Protein URE2 OS=Sugiyamaella lignohabitans GN=URE2 PE=3 SV=1
Q6CD77_YARLI74.615%2601.59e-148Protein URE2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C03069g PE=3 SV=1
A0A1E3PHZ9_9ASCO69.478%2491.13e-132Glutathione S-transferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83111 PE=3 SV=1
UniRef50_A0A0J9XBH767.910%2685.54e-130Protein URE2 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XBH7_GEOCN
URE2_CANAL60.870%2531.58e-115Protein URE2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=URE2 PE=3 SV=1
URE2_YEAST58.498%2537.53e-112Transcriptional regulator URE2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=URE2 PE=1 SV=1
A0A1E4TKK6_9ASCO54.959%2424.08e-95Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_18585 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2261
Predicted cleavage: 120

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 393

Detailed signature matches

  1. Family IPR017298
    Transcriptional regulator Ure2
    1. PIRSF037861 (Prion_...)
  2. Domain IPR012336
    Thioredoxin-like fold
    1. SSF52833 (Thioredox...)
  3. Domain IPR004045
    Glutathione S-transferase, N-terminal
    1. PF02798 (GST_N)
    2. PS50404 (GST_NTER)
  4. Domain IPR010987
    Glutathione S-transferase, C-terminal-like
    1. SSF47616 (GST C-ter...)
    2. PS50405 (GST_CTER)
  5. Domain IPR004046
    Glutathione S-transferase, C-terminal
    1. PF00043 (GST_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.20.10...
  2. G3DSA:3.40.30.10
  3. cd03048 (GST_N_Ure2...)
  4. mobidb-lite (disord...)

Residue annotation

  1. C-terminal domain ...
  2. GSH binding site (...
  3. dimer interface cd...

Protein sequence

>MIA_02727_1
MSQQTPKKPVVVSNLSSALANIHIGSQNQNQQSSQYRNPPFGGQQIFTNNNNPSSNNNNTNGSSHHLNNSSNGSSTNISS
NESNNIPTANNINHMNGNLIPNQYPIINNNTNNAFVQRQDSRSQFLASNIDIPMSQTPDDAPLDRIALYRKNPPTEGISL
FSHRSAPNGFKIAVVLSELGFKYKTFYLDFKRNEQRSPYYLSMNPNARVPAIIDHDNNDHTVWESGSIIIYLCQRAGRDC
PIWSDDICEQSSITSWLFFQASGHAPMIGQALHFKYFHPERINSALERYVNEVRRIYGVVEMRLAELREQMIMEMDDESF
SLGTSALSESKYFADPVWLVGNRLTVADLSFVTWNHVVDRIDIDLKNEFPEVYKWTQMMLSRPSVKRALSGLE

GO term prediction

Biological Process

GO:0006808 regulation of nitrogen utilization

Molecular Function

GO:0003714 transcription corepressor activity
GO:0005515 protein binding

Cellular Component

None predicted.