Protein

MIA_02717_1

Length
228 amino acids

Browser: contig03:1533254-1534017+

Protein function

EGGNOG:0PM98PGUG_04304adenylate kinase
SGD closest match:S000000972ADK2GTP:AMP phosphotransferase, mitochondrial
CGD closest match:CAL0000185135ADK2GTP:AMP phosphotransferase, mitochondrial

Protein alignments

%idAln lengthE-value
A0A0J9X5B6_GEOCN71.749%2231.71e-105GTP:AMP phosphotransferase, mitochondrial OS=Geotrichum candidum GN=ADK2 PE=3 SV=1
A0A060TC60_BLAAD66.372%2264.44e-100GTP:AMP phosphotransferase, mitochondrial OS=Blastobotrys adeninivorans GN=ADK2 PE=3 SV=1
A0A167DS02_9ASCO64.474%2282.33e-99GTP:AMP phosphotransferase, mitochondrial OS=Sugiyamaella lignohabitans GN=ADK2 PE=3 SV=1
MCA_03096_167.241%2326.01e-96MCA_03096_1
A0A1E3PKW0_9ASCO60.177%2261.20e-89GTP:AMP phosphotransferase, mitochondrial OS=Nadsonia fulvescens var. elongata DSM 6958 GN=ADK2 PE=3 SV=1
A0A1E4TCT0_9ASCO59.641%2231.47e-89GTP:AMP phosphotransferase, mitochondrial OS=Tortispora caseinolytica NRRL Y-17796 GN=ADK2 PE=3 SV=1
UniRef50_A0A1D2VEB359.821%2242.68e-85GTP:AMP phosphotransferase, mitochondrial n=92 Tax=Fungi TaxID=4751 RepID=A0A1D2VEB3_9ASCO
Q6C0A1_YARLI59.735%2261.21e-88GTP:AMP phosphotransferase, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ADK2 PE=3 SV=1
KAD3_YEAST61.881%2021.93e-80GTP:AMP phosphotransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADK2 PE=1 SV=1
A0A1D8PQH7_CANAL57.078%2191.33e-79GTP:AMP phosphotransferase, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ADK2 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6014

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 228

Detailed signature matches

  1. Family IPR000850
    Adenylate kinase/UMP-CMP kinase
    1. PR00094 (ADENYLTKNASE)
    2. MF_00235 (Adenylate...)
    3. cd01428 (ADK)
  2. Family IPR006259
    Adenylate kinase subfamily
    1. TIGR01351
  3. Family IPR028586
    Adenylate kinase 3/4, mitochondrial
    1. MF_03169 (Adenylate...)
  4. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  5. Domain IPR007862
    Adenylate kinase, active site lid domain
    1. PF05191 (ADK_lid)
  6. SITE IPR033690
    Adenylate kinase, conserved site
    1. PS00113 (ADENYLATE_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. NON_CYTOPLASM... (N...)
  3. PF00406 (ADK)
  4. SIGNAL_PEPTIDE (Sig...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)

Residue annotation

  1. AMP-binding site c...
  2. ATP-AMP (Ap5A)-bin...

Protein sequence

>MIA_02717_1
MSNIFRPIRLLLLGAPGSGKGTQTSRILKDFPQICAISSGDLLRQQIKLGTPIGKEAEAIIKKGDLIPDDSIVSLIKEEL
NAKSLLNASSSWLLDGFPRNATQAHVLETTLSSHNANLNLVVELDVPEEVILDRIENRWVHIPSGRVYNLTFNPPKVPGR
DDITGEPLSKRPDDNPVTFKERIDTYKHQTLPLLEYYKKFGILRSVKGETSDIIYPQLKELLLKEFSK

GO term prediction

Biological Process

GO:0006139 nucleobase-containing compound metabolic process

Molecular Function

GO:0004017 adenylate kinase activity
GO:0005524 ATP binding
GO:0016776 phosphotransferase activity, phosphate group as acceptor
GO:0019205 nucleobase-containing compound kinase activity

Cellular Component

GO:0005739 mitochondrion