Protein

MCA_03096_1

Length
249 amino acids

Browser: contigB:3360622-3361372+

RNA-seq: read pairs 1417, FPKM 70.0, percentile rank 72.6% (100% = highest expression)

Protein function

KEGG:K00939adk adenylate kinase [EC:2.7.4.3]
EGGNOG:0PM98PGUG_04304adenylate kinase
SGD closest match:S000000972ADK2GTP:AMP phosphotransferase, mitochondrial
CGD closest match:CAL0000185135ADK2GTP:AMP phosphotransferase, mitochondrial

Protein alignments

%idAln lengthE-value
MIA_02717_169.26%2444e-99MIA_02717_1
A0A0J9X5B6_GEOCN61.16%2422e-90GTP:AMP phosphotransferase, mitochondrial OS=Geotrichum candidum GN=ADK2 PE=3 SV=1
A0A167DS02_9ASCO57.51%2337e-88GTP:AMP phosphotransferase, mitochondrial OS=Sugiyamaella lignohabitans GN=ADK2 PE=3 SV=1
A0A060TC60_BLAAD55.93%2362e-83GTP:AMP phosphotransferase, mitochondrial OS=Blastobotrys adeninivorans GN=ADK2 PE=3 SV=1
Q6C0A1_YARLI54.08%2338e-79GTP:AMP phosphotransferase, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ADK2 PE=3 SV=1
A0A1E3PKW0_9ASCO53.45%2321e-76GTP:AMP phosphotransferase, mitochondrial OS=Nadsonia fulvescens var. elongata DSM 6958 GN=ADK2 PE=3 SV=1
UniRef50_A0A1D2VEB351.44%2433e-72GTP:AMP phosphotransferase, mitochondrial n=92 Tax=Fungi TaxID=4751 RepID=A0A1D2VEB3_9ASCO
A0A1E4TCT0_9ASCO53.68%2311e-73GTP:AMP phosphotransferase, mitochondrial OS=Tortispora caseinolytica NRRL Y-17796 GN=ADK2 PE=3 SV=1
A0A1D8PQH7_CANAL53.48%2302e-71GTP:AMP phosphotransferase, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ADK2 PE=3 SV=1
KAD3_YEAST55.45%2201e-70GTP:AMP phosphotransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADK2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6404

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 249

Detailed signature matches

  1. Family IPR000850
    Adenylate kinase/UMP-CMP kinase
    1. PR00094 (ADENYLTKNASE)
    2. MF_00235 (Adenylate...)
    3. cd01428 (ADK)
  2. Family IPR006259
    Adenylate kinase subfamily
    1. TIGR01351
  3. Family IPR028586
    Adenylate kinase 3/4, mitochondrial
    1. MF_03169 (Adenylate...)
  4. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  5. Domain IPR007862
    Adenylate kinase, active site lid domain
    1. PF05191 (ADK_lid)
  6. SITE IPR033690
    Adenylate kinase, conserved site
    1. PS00113 (ADENYLATE_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. PF00406 (ADK)
  3. mobidb-lite (disord...)

Residue annotation

  1. AMP-binding site c...
  2. ATP-AMP (Ap5A)-bin...

Protein sequence

>MCA_03096_1
MSTKTNILRPIRLLLLGAPGSGKGTQTSRLLKDFPQIHSISSGDLLRQEIKQGSEIGQKYASIIKTGGLIPDTSIVELIK
QELISKNFLSSSSSSSSTTINEEKKNNSWLLDGFPRTLNQAKMLDKMLEQGDSNNNNTLNLVVELDVPESVILERIENRW
VHVPSGRVYNLTFNPPKVEGKDDVTGEPLSKRPDDNPATFKERIDLYKSETLPLLDYYAGRGIVRTVQGETSDIIYPKLK
ELLLKEFSL

GO term prediction

Biological Process

GO:0006139 nucleobase-containing compound metabolic process

Molecular Function

GO:0004017 adenylate kinase activity
GO:0005524 ATP binding
GO:0016776 phosphotransferase activity, phosphate group as acceptor
GO:0019205 nucleobase-containing compound kinase activity

Cellular Component

GO:0005739 mitochondrion