Protein

MIA_02690_1

Length
403 amino acids

Browser: contig03:1461896-1463108-

Protein function

EGGNOG:0PJPTFG04458.1K05916 nitric oxide dioxygenase EC 1.14.12.17
SGD closest match:S000003466YHB1Flavohemoprotein
CGD closest match:CAL0000179202YHB1Flavohemoprotein

Protein alignments

%idAln lengthE-value
A0A0J9XEW3_GEOCN57.282%4123.96e-170Similar to Saccharomyces cerevisiae YGR234W YHB1 Nitric oxide oxidoreductase OS=Geotrichum candidum GN=BN980_GECA12s03167g PE=3 SV=1
UniRef50_A0A0J9XEW357.282%4128.10e-167Similar to Saccharomyces cerevisiae YGR234W YHB1 Nitric oxide oxidoreductase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XEW3_GEOCN
MCA_01601_155.854%4102.60e-158MCA_01601_1
A0A060T0W4_BLAAD40.633%4112.04e-96ARAD1C11660p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C11660g PE=3 SV=1
A0A167EK10_9ASCO39.609%4091.71e-87Yhb1p OS=Sugiyamaella lignohabitans GN=YHB1 PE=3 SV=1
A0A1E3PJ88_9ASCO39.756%4104.63e-86Nitric oxide dioxygenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83447 PE=3 SV=1
FHP_CANAL37.965%4037.22e-83Flavohemoprotein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=YHB1 PE=2 SV=1
Q6CB74_YARLI39.250%4004.80e-82YALI0C21362p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C21362g PE=3 SV=1
FHP_YEAST33.088%4082.62e-61Flavohemoprotein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YHB1 PE=1 SV=2
A0A1E4TD25_9ASCO27.841%1761.64e-11NADH-cytochrome b5 reductase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_4288 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1312

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 403

Detailed signature matches

  1. Family IPR000951
    Phthalate dioxygenase reductase
    1. PR00409 (PHDIOXRDTASE)
  2. Domain IPR009050
    Globin-like
    1. SSF46458 (Globin-like)
  3. Domain IPR000971
    Globin
    1. PS01033 (GLOBIN)
  4. Domain IPR017938
    Riboflavin synthase-like beta-barrel
    1. SSF63380 (Riboflavi...)
  5. Domain IPR017927
    Ferredoxin reductase-type FAD-binding domain
    1. PS51384 (FAD_FR)
  6. Domain IPR008333
    Oxidoreductase, FAD-binding domain
    1. PF00970 (FAD_binding_6)
  7. Domain IPR001433
    Oxidoreductase FAD/NAD(P)-binding
    1. PF00175 (NAD_binding_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.49...
  2. G3DSA:2.40.30.10
  3. G3DSA:3.40.50.80
  4. SSF52343 (Ferredoxi...)
  5. cd06184 (flavohem_l...)
  6. cd08922 (FHb-globin)

Residue annotation

  1. heme binding site ...
  2. NAD- and FAD-bindi...
  3. FAD binding site c...
  4. FAD binding pocket...
  5. FAD binding motif ...
  6. phosphate binding ...
  7. beta-alpha-beta st...
  8. NAD binding pocket...
  9. Heme binding pock...

Protein sequence

>MIA_02690_1
MPLTPEQVNIIKACVPILKKGGVTLTTRFYQNMLSENPEVKGIFNQAHQATGAQPRALAHSLLLYATYIDDLSKLTDLVE
RITAKHVVLNIQPEGYAIVGKYLIATMKEVLGEDVATPAVLEAWTAAYTDLAGLLIGIEEKMYQANEWRGYRDFVVQQKI
QETPDVVSLVLAPKDGRGVKPGKPGQFIGIKLNDKSYFADSAGTVRREYTLSDISDGKTFRISVKKIPNGKASGFIHDVL
KVGDIVEVAPPEGDFVLAEPETTKNIIFIAGGIGITPIVSLSKQVVSQYPSVSATLVHAVHNPEDQPFRNELSSLEVESK
GKYKVVRYYSKLTSTDAPNKTGHISKEDIKQLLPTNPEELDNTHIYYLGPLSFMTDVSKYLSELGVKHTHREFFLPDQSL
VVA

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016491 oxidoreductase activity
GO:0020037 heme binding

Cellular Component

None predicted.