Protein
MIA_02673_1
Length
492 amino acids
Browser: contig03:1424366-1425955+
Protein function
| EGGNOG: | 0PGBS | HER2 | Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) |
|---|---|---|---|
| SGD closest match: | S000004907 | HER2 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial |
| CGD closest match: | CAL0000174814 | HER2 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_04116_1 | 69.76% | 496 | 0.0 | MCA_04116_1 |
| A0A0J9X8R2_GEOCN | 58.01% | 493 | 0.0 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial OS=Geotrichum candidum GN=HER2 PE=3 SV=1 |
| UniRef50_A0A0J9X8R2 | 58.01% | 493 | 0.0 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial n=4 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X8R2_GEOCN |
| A0A060T486_BLAAD | 56.08% | 485 | 3e-171 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial OS=Blastobotrys adeninivorans GN=HER2 PE=3 SV=1 |
| A0A1E3PMN1_9ASCO | 47.86% | 491 | 1e-150 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial OS=Nadsonia fulvescens var. elongata DSM 6958 GN=HER2 PE=3 SV=1 |
| A0A1E4TKC0_9ASCO | 47.10% | 482 | 5e-133 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial OS=Tortispora caseinolytica NRRL Y-17796 GN=HER2 PE=3 SV=1 |
| A0A167F5D0_9ASCO | 54.45% | 382 | 5e-131 | Glutamyl-tRNA(Gln) amidotransferase subunit HER2 OS=Sugiyamaella lignohabitans GN=HER2 PE=4 SV=1 |
| GATA_YARLI | 47.14% | 454 | 8e-130 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=HER2 PE=3 SV=1 |
| GATA_YEAST | 43.01% | 479 | 2e-117 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HER2 PE=1 SV=1 |
| GATA_CANAL | 46.12% | 438 | 1e-115 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HER2 PE=3 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9170
Predicted cleavage: 37
Protein family membership
- Glutamyl-tRNA(Gln) amidotransferase A subunit (IPR004412)
Domains and repeats
-
Domain
1
50
100
150
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250
300
350
400
450
492
Detailed signature matches
Protein sequence
>MIA_02673_1 MSKISSSSVRKQAEKYLSRISSKNTSYNALVSFRRPEAILSDIESSIEKSGPLSGSFYTLKDNFCTTELPTACASKSLQG YHSPYSSTAHKLLESAGGIFLGKTNMDEFAMGSNNLTSNLYQPPINPIFSDAELNPRSTGGSSGGSAAAVAAEMCDFSLG SDTGGSVRLPAAYCGVVGFKPTYGRISRYGLVAYAQSLDTVGILAKDIATTEKIYHVLNQHDPNDPTSLSKSIRKKLDYD FPKKFSQEGESKKTYKIGIIHETNLQDLDPFVRQAWVDSLESLRSRGHEIVTVSVPSLKHALPVYFILSPSEASSNLARY DGIRYGHRAEKDREGDILYAATRAEGFGSEVQRRILLGVFNLSSEFFGNHFQQAQKVRRKIQLEYNSIFSFPNVDSSLQH FQADSDKTVDVVLSPASKTIAPTHEDIFNSEKGNGAVKAYVNDVLTVPSSIAGLPSISVPWGKGKDTVGIQITGQFGDDK TVLEVARLLELQ
GO term prediction
Biological Process
GO:0006412 translation
Molecular Function
GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
Cellular Component
GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex