Protein

MIA_02668_1

Length
2,678 amino acids


Browser: contig03:1401233-1409317+

Protein function

EGGNOG:0PKXQGAF
SGD closest match:S000001409SLN1Osmosensing histidine protein kinase SLN1
CGD closest match:CAL0000185875CHK1Histidine protein kinase 1

Protein alignments

%idAln lengthE-value
A0A0J9XI98_GEOCN61.07%13690.0Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA18s01990g PE=4 SV=1
UniRef50_A0A0J9XI9861.07%13690.0Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XI98_GEOCN
W0TYQ0_YARLI50.59%13540.0YALI0B15722p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B15722g PE=4 SV=1
MCA_04109_165.33%8510.0MCA_04109_1
A0A060T2X6_BLAAD57.37%8890.0ARAD1C32362p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32362g PE=4 SV=1
A0A167DXH5_9ASCO47.39%6900.0Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_1703 PE=4 SV=1
A0A1E3PH84_9ASCO39.41%8171e-155Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_60681 PE=4 SV=1
CHK1_CANAL51.60%4074e-95Histidine protein kinase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CHK1 PE=2 SV=2
A0A1E4TFT3_9ASCO44.25%2266e-33Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31477 PE=4 SV=1
SLN1_YEAST36.07%1222e-11Osmosensing histidine protein kinase SLN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SLN1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1236

Protein family membership

None predicted.

Domains and repeats

Detailed signature matches

    1. SSF56112 (Protein k...)
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
    1. SSF52540 (P-loop co...)
    1. SSF55781 (GAF domai...)
    1. PF01590 (GAF)
    2. SM00065 (gaf_1)
    1. cd00082 (HisKA)
    2. SSF47384 (Homodimer...)
    3. SM00388 (HisKA_10)
    4. PF00512 (HisKA)
    1. PS50109 (HIS_KIN)
    1. PF02518 (HATPase_c)
    2. SSF55874 (ATPase do...)
    3. SM00387 (HKATPase_4)
    1. PR00344 (BCTRLSENSOR)
    1. SSF52172 (CheY-like)
    1. PS50110 (RESPONSE_R...)
    2. PF00072 (Response_reg)
    3. cd00156 (REC)
    4. SM00448 (REC_2)
    1. PS50005 (TPR)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PF13191 (AAA_16)
  2. TRANSMEMBRANE (Tran...)
  3. cd00075 (HATPase_c)
  4. mobidb-lite (disord...)

Residue annotation

  1. dimer interface cd...
  2. phosphorylation si...
  3. ATP binding site c...
  4. Mg2+ binding site ...
  5. G-X-G motif cd00075
  6. active site cd00156
  7. intermolecular rec...
  8. dimerization inter...
  9. active site cd00156
  10. phosphorylation si...
  11. intermolecular rec...
  12. dimerization inter...

Protein sequence

>MIA_02668_1
MLDSTNTSSAEPTLSDLAAYRRRPMMSVETNRCSSSPSSPFYPPKQATSTDSYFGFGSKQADTSENSSGLCPSSENSTCT
SESYESIPLLPSLSSVANMSHRSFHSTGTNNHAASSATWSMNDTASLDKYCARPFDDLSCPAIPSIPGYSDLDPILPHYP
QSVSMYRATHISSGQKVFIKAANRGNLDDLIRIRHEWSISSAVRQPPSRIESESESTSPIITQSLAHLNGILRSESCTRF
SSNSRSIFLTYNDADPGLITLREKFISTTAPERLQPETEPVPRTSETLAEILTIVIRVVEIITQTHFQGITHNGLTSSSI
FVSPKDNSVFISGWDFSFPLKAEDTSHGYRKTYLNNITACLGYVSPETTGLNHRLVDYRSDFYSIGCILYELTTGCLPFT
SEDPFELTRMHVLRTPSPPHLIAPWVPTSLSSIILKLMEKKADDRYQTSKLIFSDLTHALNVLRQRPQLHSSEDYEEFVP
NAVPQVSQIFLMPQVLYGRENEINLLRSCYKRKEERDFQFIFINGEPGSGKTRLVNELERSSLSRNAFFCSSKFDPYQRG
PPFYSIVTVLKEIVHQILCGSVQSITRWRDNILSNLKVELAVLFEPIPELRYLLGHEYSKLLPTPRHLGPVPRELRFKYV
VKSLFCLFGSQGLTIFLDDVQWCPQTELDFFHELATFAIENFGSTNGIHIIFVCASTLDSPRYHELVGLARDLSLHYEVV
NLEPLGFNAVQYMLNDTLTTCTTSTKKLQTGGGSNTANGGTGAGGAGNGTSQDHKPASLNIGPSAVDSTSLSSTASASVN
SFDLGSGNGCNTSPIPAPGVGLATVAAAGLSSKDPYFIFSSNVEPQVSSLSQIVYNVTNGNPLFITLILNYMNRNKLLYY
DESNRSLGGRWKVDFESFQPSDLPQSITSIVIETVNKLPQNTITILKYAACICSNSFTLEDLAISAGVTFSEAAQALNYA
LEGQLIMPTTVQYKFPFPDPIGTTNIEIQGEEIRSVAASATYRFFHDLVQQAVYSLLSSEEAIETHRSIGMRLLDPSNNN
NVITSQCLPKLPEQHAVHKIIEIANQLKNATPIVTDSERYIYLSSAVQAGDAVYAMSDFDMAYSYFDTARQILPSNAQKT
HPAYFKHIYLSLVELQYNRRNFHECLDLIDEVFDKFSENIDKAALLRTQTKAEYGLYRPEAAITTGIRALNLLGFPMQED
EDWNAKNHAKIRHHIPLTFTEIRGLVNQAPATDPALILAQEVISIMTVPIILSYRPHLFRSLIYTSVVGFVDHGATASCS
FSLLSLASLFQRAGENTNLLRAYEYSKLAIVTLEHDNAVGLDFGINIYEYYALTLAIYFEPLSEVIRYYDLVLSSGQTFD
NHCGMLSLSYDLRPLCKFLAAEPLSGVLSYFEQMRPVNLENTDNAGKLWIQLHSQAVANILGIGNSDPCVFSGAYIGDPN
DTINVLNSNYELKYVYYVVKLILAVIHRQKYLAADIICVKLPKVMSEFPVTLYHVIVTFFGALAIIDKDSRTEQEMELLN
QFARDLEDWSQTNPSMFMQKHLLVQAEIHKNTQNSIITLDTYEEAIAYAINEGFINDAALINERCGDYLLQHSRRRSMSY
FRESVRLYTLWGAHKRASQITAKFHDLPNMHLSNSMIDIASAPITSVENVSRPGSTRQSGRQIILNNSSANTHSSSPLRW
ILSNLFREDDSNTSSGDNATDIKRKKNSLTISEAECNALMLQPTTPTTVTTFSAAAAISAQSTPTYKGTSSDLIPLAAMT
RYGNGAGNYSSSSGTGRDSGNGDLELKTALQYCLDISEAIEVESVLEKFVNSVMKSSGADYCVFVTLDVDEPYIEAIGIL
NGITLYNHRPVNGRFDVPLSVIFQVSSSGQLVSRGTSSRTHSDKQFELLFGHDTYFQTRHSKSILCMPIQNQLKVIGVLY
IEHQSLDDIFTRPRIELLGLLCTQVVMSLEKAKLYHQMEVAKKTAEEATEEKASFLANMSHEIRTPFNALLSCSIFLLDT
KLSEVQREYVEIIRSSAMLTLNIIDAILAFSKIEHGSITLDNAPFSLRECVESAIQLVAEPAATKDLELVHLNKCGDIDI
VYGDVTRVRQIIINLVGNAVKFTSAGYIVVETQAEKVSSDNRYGFVIAVKDTGIGIPKSARSKIFRAFSQVDGSSRRLYG
GSGLGLAISKKLAELMGGSLTFESNVDDAASSISAGGTNGSTSNRSSISGNGSRVAIETGESEEALQSQQEQGSQKLANS
SGDSSGFESDRATGAGTTFWFDFVAVAQKPEDEEKETKAMREAFLKKRVLVVDPFEKARESLVFELERVGFDVECCASYK
EAIALVAMAMSKKEKIYSLVFMNGGFVNAECKQIIEIREKSPQTQVVFMTRFGAPIPEDGKEKGIAAILMRPAQRRRLLD
IVQGALKFSGVGGNAMSGADGGGVMSLEYEVGRNGSRGGFEEEEADVDGGSNDEGVGVNGGEDGGFYKMSNNMSLTNLEH
LHTDADDMIGPSKPLGRLMADSKAASGSRPHSNSGRRNSGNGSRKSLSADHPLKILLAEDNPINTRVALQHLKRMGYEAE
HAKDGVEVVEKCIEEVACGRSMYDCILMDIQMPRKDGIAAAQELMSLYGEKERPAIIALTANAAGEDRQNCLAVGMANYI
AKPILPADLARVLLGVVPLHKRVLEGDGESNGDDPKNE

GO term prediction

Biological Process

GO:0000160 phosphorelay signal transduction system
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0016310 phosphorylation

Molecular Function

GO:0000155 phosphorelay sensor kinase activity
GO:0004672 protein kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups

Cellular Component

None predicted.