MCA_04109_1

Protein

Length

2,545 amino acids

Gene name: CHK1

Description: Histidine protein kinase 1

Browser: contigC:2036482-2044282+

RNA-seq: read pairs 1012, FPKM 4.9, percentile rank 17.3% (100% = highest expression)

Protein function

Annotation:		CHK1	Histidine protein kinase 1
KEGG:	K19690	CHK1	osomolarity two-component system, sensor histidine kinase CHK1 [EC:2.7.13.3]
EGGNOG:	0PKXQ		GAF
SGD closest match:	S000001249	SKN7	Transcription factor SKN7
CGD closest match:	CAL0000185875	CHK1	Histidine protein kinase 1

Protein alignments

	%id	Aln length	E-value
A0A060T2X6_BLAAD	55.78%	2198	0.0	ARAD1C32362p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32362g PE=4 SV=1
UniRef50_A0A060T2X6	55.78%	2198	0.0	ARAD1C32362p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T2X6_BLAAD
W0TYQ0_YARLI	45.56%	2261	0.0	YALI0B15722p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B15722g PE=4 SV=1
A0A0J9XI98_GEOCN	60.36%	1486	0.0	Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA18s01990g PE=4 SV=1
A0A167DXH5_9ASCO	49.26%	1222	0.0	Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_1703 PE=4 SV=1
MIA_02668_1	65.33%	851	0.0	MIA_02668_1
A0A1E3PH84_9ASCO	50.97%	565	9e-148	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_60681 PE=4 SV=1
CHK1_CANAL	50.35%	425	2e-106	Histidine protein kinase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CHK1 PE=2 SV=2
A0A1E4TFT3_9ASCO	44.30%	237	7e-44	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31477 PE=4 SV=1
SKN7_YEAST	32.81%	128	2e-11	Transcription factor SKN7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SKN7 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0083
Predicted cleavage: 45

Protein family membership

None predicted.

Domains and repeats

Domain
154 - 488
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)
517 - 571
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
618 - 760
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
1,021 - 1,621
Tetratricopeptide-like helical domain (IPR011990)
1,914 - 1,997
Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (IPR003661)
2,086 - 2,100
Signal transduction histidine kinase-related protein, C-terminal (IPR004358)
2,104 - 2,114
Signal transduction histidine kinase-related protein, C-terminal (IPR004358)
2,121 - 2,139
Signal transduction histidine kinase-related protein, C-terminal (IPR004358)
2,414 - 2,540
CheY-like superfamily (IPR011006)
Signal transduction response regulator, receiver domain (IPR001789)
Domain
1,721 - 1,934
GAF domain-like (IPR029016)
GAF domain (IPR003018)
1,938 - 2,160
Histidine kinase domain (IPR005467)
Domain
1,986 - 2,169
Histidine kinase-like ATPase, C-terminal domain (IPR003594)

1 500 1000 1500 2000 2545

Detailed signature matches

IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  201 - 482
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. PS50011 (PROTEIN_KI...)
  
  154 - 488
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
2. PF00069 (Pkinase)
  
  319 - 480
  
  Pfam
  PF00069 (Pkinase)
3. SM00220 (serkin_6)
  
  195 - 487
  
  SMART
  SM00220 (serkin_6)
IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  618 - 760
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  517 - 571
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
IPR011990

Tetratricopeptide-like helical domain
1. G3DSA:1.25.40.10
  
  1,021 - 1,621
  
  GENE3D
  G3DSA:1.25.40.10 (G3DSA:1.25.40.10)
IPR029016

GAF domain-like
1. SSF55781 (GAF domai...)
  
  1,743 - 1,923
  
  SUPERFAMILY
  SSF55781 (GAF domain-like)
2. G3DSA:3.30.45...
  
  1,721 - 1,934
  
  GENE3D
  G3DSA:3.30.450.40 (G3DSA:3.30.450.40)
IPR003018

GAF domain
1. PF01590 (GAF)
  
  1,760 - 1,908
  
  Pfam
  PF01590 (GAF)
2. SM00065 (gaf_1)
  
  1,759 - 1,919
  
  SMART
  SM00065 (gaf_1)
IPR003661

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain
1. cd00082 (HisKA)
  
  1,935 - 1,992
  
  CDD
  cd00082 (HisKA)
2. SSF47384 (Homodimer...)
  
  1,914 - 1,997
  
  SUPERFAMILY
  SSF47384 (Homodimeric domain of signal transducing histidine kinase)
3. SM00388 (HisKA_10)
  
  1,931 - 1,996
  
  SMART
  SM00388 (HisKA_10)
4. PF00512 (HisKA)
  
  1,932 - 1,996
  
  Pfam
  PF00512 (HisKA)
IPR005467

Histidine kinase domain
1. PS50109 (HIS_KIN)
  
  1,938 - 2,160
  
  PROSITE profiles
  PS50109 (HIS_KIN)
IPR003594

Histidine kinase-like ATPase, C-terminal domain
1. G3DSA:3.30.56...
  
  2,000 - 2,169
  
  GENE3D
  G3DSA:3.30.565.10 (G3DSA:3.30.565.10)
2. PF02518 (HATPase_c)
  
  2,044 - 2,156
  
  Pfam
  PF02518 (HATPase_c)
3. SSF55874 (ATPase do...)
  
  1,986 - 2,156
  
  SUPERFAMILY
  SSF55874 (ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase)
4. SM00387 (HKATPase_4)
  
  2,044 - 2,160
  
  SMART
  SM00387 (HKATPase_4)
IPR004358

Signal transduction histidine kinase-related protein, C-terminal
1. PR00344 (BCTRLSENSOR)
  
  2,104 - 2,114
  
  PRINTS
  PR00344 (BCTRLSENSOR)
  
  2,121 - 2,139
  
  PRINTS
  PR00344 (BCTRLSENSOR)
  
  2,086 - 2,100
  
  PRINTS
  PR00344 (BCTRLSENSOR)
IPR011006

CheY-like superfamily
1. SSF52172 (CheY-like)
  
  2,414 - 2,540
  
  SUPERFAMILY
  SSF52172 (CheY-like)
IPR001789

Signal transduction response regulator, receiver domain
1. PS50110 (RESPONSE_R...)
  
  2,417 - 2,540
  
  PROSITE profiles
  PS50110 (RESPONSE_REGULATORY)
2. PF00072 (Response_reg)
  
  2,418 - 2,534
  
  Pfam
  PF00072 (Response_reg)
3. cd00156 (REC)
  
  2,419 - 2,540
  
  CDD
  cd00156 (REC)
4. SM00448 (REC_2)
  
  2,416 - 2,536
  
  SMART
  SM00448 (REC_2)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

1,463 - 1,473

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.10.28...

1,935 - 1,992

GENE3D
G3DSA:1.10.287.130 (G3DSA:1.10.287.130)
G3DSA:1.10.51...

311 - 502

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.40.50...

2,170 - 2,319

GENE3D
G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)

2,412 - 2,545

GENE3D
G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
G3DSA:3.40.50...

509 - 713

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
NON_CYTOPLASM... (N...)

1,497 - 2,545

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

1 - 1,443

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
PF13191 (AAA_16)

520 - 699

Pfam
PF13191 (AAA_16)
TRANSMEMBRANE (Tran...)

1,474 - 1,496

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,444 - 1,462

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
cd00075 (HATPase_c)

2,050 - 2,156

CDD
cd00075 (HATPase_c)
mobidb-lite (disord...)

1,678 - 1,738

MobiDB Lite
mobidb-lite (disorder_prediction)

2,320 - 2,375

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 20

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

dimer interface cd...

1,935F

dimer interface
1,935F, 1,939M, 1,943I, 1,946P, 1,950L, 1,952S, 1,969Y, 1,973I, 1,976S, 1,980T, 1,983I, 1,987I
CDD
cd00082 (HisKA)

1,939M

dimer interface
1,935F, 1,939M, 1,943I, 1,946P, 1,950L, 1,952S, 1,969Y, 1,973I, 1,976S, 1,980T, 1,983I, 1,987I
CDD
cd00082 (HisKA)

1,943I

dimer interface
1,935F, 1,939M, 1,943I, 1,946P, 1,950L, 1,952S, 1,969Y, 1,973I, 1,976S, 1,980T, 1,983I, 1,987I
CDD
cd00082 (HisKA)

1,946P

dimer interface
1,935F, 1,939M, 1,943I, 1,946P, 1,950L, 1,952S, 1,969Y, 1,973I, 1,976S, 1,980T, 1,983I, 1,987I
CDD
cd00082 (HisKA)

1,950L

dimer interface
1,935F, 1,939M, 1,943I, 1,946P, 1,950L, 1,952S, 1,969Y, 1,973I, 1,976S, 1,980T, 1,983I, 1,987I
CDD
cd00082 (HisKA)

1,952S

dimer interface
1,935F, 1,939M, 1,943I, 1,946P, 1,950L, 1,952S, 1,969Y, 1,973I, 1,976S, 1,980T, 1,983I, 1,987I
CDD
cd00082 (HisKA)

1,969Y

dimer interface
1,935F, 1,939M, 1,943I, 1,946P, 1,950L, 1,952S, 1,969Y, 1,973I, 1,976S, 1,980T, 1,983I, 1,987I
CDD
cd00082 (HisKA)

1,973I

dimer interface
1,935F, 1,939M, 1,943I, 1,946P, 1,950L, 1,952S, 1,969Y, 1,973I, 1,976S, 1,980T, 1,983I, 1,987I
CDD
cd00082 (HisKA)

1,976S

dimer interface
1,935F, 1,939M, 1,943I, 1,946P, 1,950L, 1,952S, 1,969Y, 1,973I, 1,976S, 1,980T, 1,983I, 1,987I
CDD
cd00082 (HisKA)

1,980T

dimer interface
1,935F, 1,939M, 1,943I, 1,946P, 1,950L, 1,952S, 1,969Y, 1,973I, 1,976S, 1,980T, 1,983I, 1,987I
CDD
cd00082 (HisKA)

1,983I

dimer interface
1,935F, 1,939M, 1,943I, 1,946P, 1,950L, 1,952S, 1,969Y, 1,973I, 1,976S, 1,980T, 1,983I, 1,987I
CDD
cd00082 (HisKA)

1,987I

dimer interface
1,935F, 1,939M, 1,943I, 1,946P, 1,950L, 1,952S, 1,969Y, 1,973I, 1,976S, 1,980T, 1,983I, 1,987I
CDD
cd00082 (HisKA)
phosphorylation si...

1,941H

phosphorylation site
1,941H
CDD
cd00082 (HisKA)
ATP binding site c...

2,055N

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,059N

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,062K

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,090V

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,092D

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,094G

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,096G

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,097I

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,124G

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,125L

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,126G

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,127L

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,143F

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,145S

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,149G

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,150T

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)

2,152F

ATP binding site
2,055N, 2,059N, 2,062K, 2,090V, 2,092D, 2,094G, 2,096G, 2,097I, 2,124G, 2,125L, 2,126G, 2,127L, 2,143F, 2,145S, 2,149G, 2,150T, 2,152F
CDD
cd00075 (HATPase_c)
Mg2+ binding site ...

2,059N

Mg2+ binding site
2,059N
CDD
cd00075 (HATPase_c)
G-X-G motif cd00075

2,094G

G-X-G motif
2,094G, 2,096G, 2,124G, 2,126G
CDD
cd00075 (HATPase_c)

2,096G

G-X-G motif
2,094G, 2,096G, 2,124G, 2,126G
CDD
cd00075 (HATPase_c)

2,124G

G-X-G motif
2,094G, 2,096G, 2,124G, 2,126G
CDD
cd00075 (HATPase_c)

2,126G

G-X-G motif
2,094G, 2,096G, 2,124G, 2,126G
CDD
cd00075 (HATPase_c)
active site cd00156

2,422E

active site
2,422E, 2,423D, 2,472D, 2,480G, 2,503T, 2,522Y, 2,525K, 2,526P
CDD
cd00156 (REC)

2,423D

active site
2,422E, 2,423D, 2,472D, 2,480G, 2,503T, 2,522Y, 2,525K, 2,526P
CDD
cd00156 (REC)

2,472D

active site
2,422E, 2,423D, 2,472D, 2,480G, 2,503T, 2,522Y, 2,525K, 2,526P
CDD
cd00156 (REC)

2,480G

active site
2,422E, 2,423D, 2,472D, 2,480G, 2,503T, 2,522Y, 2,525K, 2,526P
CDD
cd00156 (REC)

2,503T

active site
2,422E, 2,423D, 2,472D, 2,480G, 2,503T, 2,522Y, 2,525K, 2,526P
CDD
cd00156 (REC)

2,522Y

active site
2,422E, 2,423D, 2,472D, 2,480G, 2,503T, 2,522Y, 2,525K, 2,526P
CDD
cd00156 (REC)

2,525K

active site
2,422E, 2,423D, 2,472D, 2,480G, 2,503T, 2,522Y, 2,525K, 2,526P
CDD
cd00156 (REC)

2,526P

active site
2,422E, 2,423D, 2,472D, 2,480G, 2,503T, 2,522Y, 2,525K, 2,526P
CDD
cd00156 (REC)
phosphorylation si...

2,472D

phosphorylation site
2,472D
CDD
cd00156 (REC)
intermolecular rec...

2,475M

intermolecular recognition site
2,475M, 2,476P, 2,478K, 2,479D, 2,480G
CDD
cd00156 (REC)

2,476P

intermolecular recognition site
2,475M, 2,476P, 2,478K, 2,479D, 2,480G
CDD
cd00156 (REC)

2,478K

intermolecular recognition site
2,475M, 2,476P, 2,478K, 2,479D, 2,480G
CDD
cd00156 (REC)

2,479D

intermolecular recognition site
2,475M, 2,476P, 2,478K, 2,479D, 2,480G
CDD
cd00156 (REC)

2,480G

intermolecular recognition site
2,475M, 2,476P, 2,478K, 2,479D, 2,480G
CDD
cd00156 (REC)
dimerization inter...

2,525K

dimerization interface
2,525K, 2,526P, 2,527I
CDD
cd00156 (REC)

2,526P

dimerization interface
2,525K, 2,526P, 2,527I
CDD
cd00156 (REC)

2,527I

dimerization interface
2,525K, 2,526P, 2,527I
CDD
cd00156 (REC)

Protein sequence

>MCA_04109_1
MCFSSNASKKSASTSTDSNCYSSLTQFKSLSNNKKPKQNNAPRLSPTLFDSLRPLQSPSLISPSLISPGIASSLTYYSPS
QVSSSSPFASPSCHNSSSFKPGYFDSLSMATPSLGISNTNSSSNIHLSTSESTALIYPPQPNVATHYESNNNRYNNAPSL
SSSSSQSYLPSKLDTINSIPQIPDYSPLVPIYPHYEASVSMYRATRLSTGQNVLIKASSKGTLQDLTRIRHEWSVASYPT
SNANVESNNNKQLMVPPSLGDIDGILTPESCIRVGSNPPKVILTYLDQEGLMTLHEKFIPKQAKEINKPIERSKECIIEI
LEIICGVVAIIAQAHSRQITHNGLTSSSIFVGRKNKVYVAGWDFSFPLKVENSSRGYRKTYLNRVSDCLGFVSPEATGLA
HRLVDFRSDFYSIGCILYELLVGQQPFLSSDPFDLIRMHVLRTPTTPHTLCSWIPKSLSLIILKLLEKNADDRYQASNLL
LADLQLTLNILKNDDLEEDEEFVPNATPRVSPIFLIPQNIYGRDEELSILRSSYKQTEKSRFQMLFVTGEPGSGKTRLVN
ELERSSFSRNGFFCVSKFDPYQRGPPFYSIVTVLKDIVHQILCGSVLSITQWRDNIISNLKVDLAVLFDPIPELKDLLGH
EYAKLLPQPRLLGPVPRELRFKYVVKSLFCLLGAQGLTIFLDDIQWCPRTEMGFFRELASFSIENYPDVHITFICASIPD
SARVNDLITLSKDLKLHHEIINLNPLRYEAVEEMIHDVFTTCGHKKPTKLDILSTSTEISHDKSPSVLRKDFTVHKTIFN
TGYTESEALSSSSTGTDTTDNTDASDVSINMNDISHSNSTTVVDPQVKFLAQKVYKVTKGNPLFITLIMQHMHHRQLIYY
DPSTRSSNGSIGKWRVHIEQFELESIPESLTDAVVYFVSRLPANTISILKYAACICSNSFTLDDLAKGANVSYSEAANAL
HMPLDMQLLLPTTMHYKFPFPDPVGTTMVELDEDEVQSVAAASTYRFYHDLVQQSVYSLISHEAALETHKLIGLRLLGQN
YKQPQEVNRVIEISNQLKNSISIVTDEEREIYINLIVRAGDVVYGMSDFDMAYFYFDTARQLLPPNHMETFENYSRHIFL
TLVELQYNRKNFQECLDLVDKVFPIFKTNIDKAALLKTKTKAQFGLYKPEEAITTGIFALNLLGWKMQEDESWNEKNHAK
LRHRIPLALNEIRELVNRKQAQDPVMILAQEIISILTIPIILSYRPHLFRSLIYTSVTAFVRDGATASCSFSLLSLASLF
QRAGDNTNLLRAYEYSKLAIVTLEFDNAVGLDFGINIYEYYALTLAIYFEPLSEVIRYYDLVLSSGQTFDNHCGMLSLSY
DLRPLCKFLAGEPLLKVIASLKVMRPVNTNNNDATGKLWIQLHCQAVENLIGNGNTDACTLSGTYLLDTDSAEAILQSSS
ELRYVYYVIKLILAVIHQQKYLAADIISKKLPKVMSVFPVTLYHVMVTFYGALAIIDKECQKTEEDVEMLNQFCRDLEDW
SKTNPSMFLHKYLLVHAEMNKNEFNSIMTLDIYEEAIDCALREGMVQDAALINERCGDYLQKHSKRRSQVYLREALRLYT
LWGARKRASQLLARNSELSSMNGSSIDLNTSLVSDMGRSLQQLNFSNNTNSNSGTNLANATTTSSPLRWILSNLFREDGE
DSNNSNNNSNKSQSKNQKQSPLAAHDPSLSNMIDSQSSEEMVTENSSSSSNTSRHNEAADDLELKTALQYCLDISEAIEI
HSVIEKFVNSVMKSSGADYCVFVSLDQTDDQAYIDAIGILNGIKHFNHEPVNSRSDVVPVSLINHVVASGQLVSKCGTSQ
DLHNFDFLYGRDIYFQNRHFQSSILCMPIQTQFKTVGALYIEHQSLPNMFTVPRIELLGLLCTQVVVSLEKARMYHQMDL
AKKAAEEATAEKASFLANMSHEIRTPFNALLSCSIFLLDTELSEVQREYVDIIKSSAMLTLNIIDAILAFSKIEHGSITL
ENCPFSLRECVESAIQLVAEPAASKDLELVHLNKCKEDIDIVYGDVTRVRQIIINLVGNSVKFTSKGFIVVETYAEKVSP
DDRYEFVISVRDTGIGIPNSAKNKIFRAFSQVDGSSRRVYGGSGLGLAISKKLAELMGGSLSFESDSKGTTFWFDFVASV
KVKSNEGEEKLRLENNQSIGKGSRILIIDIFEKSRESLTDELKRFGFDVSCCDKIDIELIRKMQQQNKQELATAAFKGVF
IEGRLLSEEDCSVVKTIKSILPRCKVIYMTTFGKRIPTDSQEKGIDAIFMRPTQRNKLIGIVEYIVNGDKASSITNKRYI
GNGHEDGHEQGRENMNAFNSISNSNSTTTTTNNKMAGNDNNNNNNNGGDDDEKNKNRFKDIEQCLLDGRDSKNNICSSSS
STSLSALGTLSKRHPLKILLAEDNPINTRVALQHLRRMGYVADHAKDGVEVLSKCRVAFESGEGMYDCILMDIQMPNKDG
IAAAQEIIEEYSVEDRPSIIALTANAAGEDRARCLSVGMSNYIAKPILPADLASVLMRVIPIDKR

GO term prediction

Biological Process

GO:0000160 phosphorelay signal transduction system
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0016310 phosphorylation

Molecular Function

GO:0000155 phosphorelay sensor kinase activity
GO:0004672 protein kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups

Cellular Component