Protein
MIA_02660_1
Length
388 amino acids
Browser: contig03:1376902-1378252+
Protein function
| EGGNOG: | 0PMN5 | EAF3 | Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity) |
|---|---|---|---|
| SGD closest match: | S000006227 | EAF3 | Chromatin modification-related protein EAF3 |
| CGD closest match: | CAL0000193590 | EAF3 | Chromatin modification-related protein EAF3 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_05508_1 | 59.155% | 426 | 8.31e-173 | MCA_05508_1 |
| A0A0J9XES4_GEOCN | 53.494% | 415 | 5.95e-151 | Similar to Saccharomyces cerevisiae YPR023C EAF3 Esa1p-associated factor OS=Geotrichum candidum GN=BN980_GECA11s00615g PE=4 SV=1 |
| UniRef50_A0A0J9XES4 | 53.494% | 415 | 1.22e-147 | Similar to Saccharomyces cerevisiae YPR023C EAF3 Esa1p-associated factor n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XES4_GEOCN |
| A0A1E3PNT4_9ASCO | 50.663% | 377 | 1.52e-124 | MRG-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45215 PE=4 SV=1 |
| A0A060T7N6_BLAAD | 45.361% | 388 | 3.70e-118 | ARAD1D00968p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D00968g PE=4 SV=1 |
| A0A167CQA4_9ASCO | 47.230% | 379 | 3.75e-113 | Eaf3p OS=Sugiyamaella lignohabitans GN=EAF3 PE=4 SV=1 |
| EAF3_YARLI | 39.019% | 428 | 5.17e-92 | Chromatin modification-related protein EAF3 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=EAF3 PE=3 SV=1 |
| A0A1E4TJJ3_9ASCO | 50.000% | 220 | 4.73e-70 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_18276 PE=4 SV=1 |
| EAF3_YEAST | 34.913% | 401 | 1.71e-62 | Chromatin modification-related protein EAF3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EAF3 PE=1 SV=1 |
| EAF3_CANAL | 28.244% | 393 | 1.81e-50 | Chromatin modification-related protein EAF3 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=EAF3 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0135
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Domain
1
50
100
150
200
250
300
350
388
Detailed signature matches
no IPR
Unintegrated signatures
-
-
cd00024 (CHROMO)
-
mobidb-lite (disord...)
Residue annotation
-
histone binding si...
Protein sequence
>MIA_02660_1 MAPPSFPHKCLAFHGPMLYEAKTIKIWDPEEQTVRTKSSETSGEPYATKGEIPSDLPPELETKVAYYIHYKGWKSTWDEW VSDDRVLAWNEENLRTQKELKTIALAAANKRRQGAGSVAISVVSGSHNGGSALNGSSSADTAANGDSTHDNSANGRHADG DDDPNGTAHASPNVDHVAGTKRRDYSHKDEVAHSGRSTKRGRNLDLDLEKEEDYIRKPEVSLTVPDPLKSVLVDDWEFIT KEHQVVPLPREITVADMLDMYRKSVGKKKPGTAEYDIFEEVLAGVKLYFDRALGNILLYRFERQQYLSIKQKYPDKPASE IYGPEHLLRLFVSFPALIAQTNMDQQSIGILREHLQDLLRFMVDHKKKLFLKDYKNTSPQYEAISRSF
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.