Protein
MIA_02605_1
Length
573 amino acids
Browser: contig03:1244869-1246591+
Protein function
EGGNOG: | 0PFXE | MET3 | Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur- containing amino acids (By similarity) |
---|---|---|---|
SGD closest match: | S000003771 | MET3 | Sulfate adenylyltransferase |
CGD closest match: | CAL0000178072 | MET3 | Sulfate adenylyltransferase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MCA_01895_1 | 91.449% | 573 | 0.0 | MCA_01895_1 |
A0A0J9X4N8_GEOCN | 88.482% | 573 | 0.0 | Sulfate adenylyltransferase OS=Geotrichum candidum GN=MET3 PE=3 SV=1 |
A0A1E3PPW2_9ASCO | 84.642% | 573 | 0.0 | Sulfate adenylyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=MET3 PE=3 SV=1 |
A0A060T6D9_BLAAD | 83.770% | 573 | 0.0 | Sulfate adenylyltransferase OS=Blastobotrys adeninivorans GN=MET3 PE=3 SV=1 |
A0A167FDH6_9ASCO | 84.817% | 573 | 0.0 | Sulfate adenylyltransferase OS=Sugiyamaella lignohabitans GN=MET3 PE=3 SV=1 |
MET3_YARLI | 80.279% | 573 | 0.0 | Sulfate adenylyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=MET3 PE=3 SV=1 |
UniRef50_Q6CFD2 | 80.279% | 573 | 0.0 | Sulfate adenylyltransferase n=788 Tax=root TaxID=1 RepID=MET3_YARLI |
A0A1E4T9R9_9ASCO | 73.077% | 572 | 0.0 | Sulfate adenylyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=MET3 PE=3 SV=1 |
MET3_YEAST | 65.914% | 443 | 0.0 | Sulfate adenylyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET3 PE=1 SV=2 |
MET3_CANAL | 58.197% | 488 | 0.0 | Sulfate adenylyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MET3 PE=3 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1825
Protein family membership
- Sulfate adenylyltransferase (IPR027535)
- Adenylyl-sulfate kinase (IPR002891)
Domains and repeats
-
Domain
-
Domain
1
100
200
300
400
500
573
Detailed signature matches
no IPR
Unintegrated signatures
Residue annotation
-
active site cd00517
-
HXXH motif cd00517
-
flexible loop cd00...
-
ligand-binding sit...
Protein sequence
>MIA_02605_1 MSNPPHGGVLKDLIARDAPIRDELYKESETLKDIILTERQLCDLELIISGGFSPLEGFLNEKDYDGVVENLRLADGTLFP IPITLDVSKEEIEASEIKPGARITLRDFRDDVPLAIITVEDVYKPDKHKEAKHVFRGDPEHPAIRYLFNTAKEYYVGGKL QAINRLNHYDYVGLRNTPAELRSQFTKLGWSKVVAFQTRNPMHRAHRELTVRAARSRQANVLIHPVVGLTKPGDIDHFTR VRVYQAILPRYPNGLAYLSLLPLAMRMAGDREAVWHAIIRKNHGVTHFIVGRDHAGPGKNSKGVDFYGPYDAQELVEKYR DELGIEVVPFQQMTYLPDKDEYAPKDTVPEGVKTLDISGTELRKRLKLGLPIPEWFSYPEVVKVLRESHPPRTQQGFTIF LTGYHNSGKDSVGRALQVTLNQQAGRSVSLLLGETVRAELSSELGFTREDRHKNIQRIAFVASELTRSGAAVIAAPIAPY ESSRQVARETVEKAGGNFFLVHVATPLEHAEKTDRKGVYKRARNGEIKGFTGVDDPYEVPTKPDLTVDLTQISVRTAVHQ IILHLEAEGFFGN
GO term prediction
Biological Process
GO:0000096 sulfur amino acid metabolic process
GO:0000103 sulfate assimilation
Molecular Function
GO:0004020 adenylylsulfate kinase activity
GO:0004781 sulfate adenylyltransferase (ATP) activity
GO:0005524 ATP binding
Cellular Component
None predicted.