Protein

MIA_02551_1

Length
887 amino acids

Browser: contig03:1104367-1107106+

Protein function

EGGNOG:0PGCBVPS35Vacuolar protein sorting-associated protein
SGD closest match:S000003690VPS35Vacuolar protein sorting-associated protein 35
CGD closest match:CAL0000185637VPS35Vacuolar protein sorting-associated protein 35

Protein alignments

%idAln lengthE-value
A0A0J9XBQ1_GEOCN63.76%8940.0Vacuolar protein sorting-associated protein 35 OS=Geotrichum candidum GN=BN980_GECA07s01759g PE=3 SV=1
UniRef50_A0A0J9XBQ163.76%8940.0Vacuolar protein sorting-associated protein 35 n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XBQ1_GEOCN
A0A060T9H1_BLAAD58.41%9040.0Vacuolar protein sorting-associated protein 35 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D11880g PE=3 SV=1
Q6C5K0_YARLI54.89%8890.0Vacuolar protein sorting-associated protein 35 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E17413g PE=3 SV=1
MCA_01858_174.46%5130.0MCA_01858_1
A0A167EBZ7_9ASCO58.92%4992e-168Vps35p OS=Sugiyamaella lignohabitans GN=VPS35 PE=4 SV=1
Q59T42_CANAL34.53%9794e-152Vacuolar protein sorting-associated protein 35 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=VPS35 PE=3 SV=1
A0A1E3PTI6_9ASCO70.53%3026e-135Vacuolar protein sorting-associated protein 35 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81502 PE=3 SV=1
A0A1E4TAR0_9ASCO66.99%3061e-130Vacuolar protein sorting-associated protein 35 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_28229 PE=3 SV=1
VPS35_YEAST60.20%2992e-94Vacuolar protein sorting-associated protein 35 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VPS35 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1329

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 887

Detailed signature matches

  1. Family IPR005378
    Vacuolar protein sorting-associated protein 35
    1. PF03635 (Vps35)
    2. PIRSF009375 (Retrom...)
  2. Domain IPR016024
    Armadillo-type fold
    1. SSF48371 (ARM repeat)
  3. Domain IPR011989
    Armadillo-like helical
    1. G3DSA:1.25.10.10
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil

Protein sequence

>MIA_02551_1
MSSAVTVITAEEQARKLEESLAVIHQQEALMRKCLESKGKLMDALKHASTFLAELRTSLLSPKQYYELYIAVFDALSYLG
GYLRDNHKTFHLADLYELVQYAGMWXPILEGNIVPRLYLMITVGTAYMSVPDAPVKEIMKDMLEMCRGVQHPIRGLFLRY
YLSQTARDHLPIGDSDGPGGNLQDSIQFIVTNFIEMNKLWVRLQHQGHSREREKRTKERKELQILVGSNLVRLSQLEGID
KEYYRSTILNAILEQIVQCRDVIAQEYLLDVVTQVFPDEFHLYTLDLFLNATANLHPETSVKKVILTMVNRLADFAAREA
ENESSEEVDALTASLNAATVKESVKEDTPSDDNTNKDDKDKEEADKPAKEEEPSKPEPPKEVATFRGVPANIDLFEIFWA
FFQKLLETRPDLSLEDISALLGGIARLSLNCYPDRTENIDKILDFILQKVKPSAEEEPVSPTTTENVLDLLKMLIQTYPQ
MLTVLSLKNFIPLLESQPTATQKAVASSVAYDILKGGNKITTVEDTEGVFGLVRIVIREGVDSTKNKHSSDGIAKLMGGE
SPSTTFGEDDKDVPDEVVADQGNLAKMVHLLYNPDAEIHAKLLTAARKALAEGGAFVRYTYPALVTNAMRLVRRFKAREP
VDAEWKDKVSSTFKFVQLVIGEIYRVGSSDKALRLYVNAASIADQVNVEQAAYEFFAEAFTVYEEAVSDSRAQYQAIVLI
AGVLQNTRNFASDSYDTLVSKCALYGSKLLKKPDQCRAVYLASHLWWAVEIPALGETEEDSEFFRDGNRVLECLQRALRV
ADACMDVAVSVELFVEILNRYLYFFYRGNDKVTVKYITGLIELIQRNLDSMTNDGNVSDSPRKHFERTLQFITDQKEEDE
RFQKIVW

GO term prediction

Biological Process

GO:0015031 protein transport
GO:0042147 retrograde transport, endosome to Golgi

Molecular Function

GO:0005488 binding
GO:0008565 protein transporter activity

Cellular Component

GO:0030904 retromer complex