Protein

MCA_01858_1

Length
911 amino acids

Gene name: VPS35

Description: Vacuolar protein sorting-associated protein 35

Browser: contigA:5705543-5708344-

RNA-seq: read pairs 4653, FPKM 63.0, percentile rank 70.3% (100% = highest expression)

Protein function

Annotation:VPS35Vacuolar protein sorting-associated protein 35
KEGG:K18468VPS35 vacuolar protein sorting-associated protein 35
EGGNOG:0PGCBVPS35Vacuolar protein sorting-associated protein
SGD closest match:S000003690VPS35Vacuolar protein sorting-associated protein 35
CGD closest match:CAL0000185637VPS35Vacuolar protein sorting-associated protein 35

Protein alignments

%idAln lengthE-value
MIA_02551_174.46%5130.0MIA_02551_1
A0A0J9XBQ1_GEOCN61.13%5120.0Vacuolar protein sorting-associated protein 35 OS=Geotrichum candidum GN=BN980_GECA07s01759g PE=3 SV=1
UniRef50_A0A0J9XBQ161.13%5120.0Vacuolar protein sorting-associated protein 35 n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XBQ1_GEOCN
A0A060T9H1_BLAAD56.71%4990.0Vacuolar protein sorting-associated protein 35 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D11880g PE=3 SV=1
A0A167EBZ7_9ASCO57.17%4951e-172Vps35p OS=Sugiyamaella lignohabitans GN=VPS35 PE=4 SV=1
Q6C5K0_YARLI50.49%5133e-157Vacuolar protein sorting-associated protein 35 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E17413g PE=3 SV=1
A0A1E3PTI6_9ASCO68.75%3042e-138Vacuolar protein sorting-associated protein 35 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81502 PE=3 SV=1
A0A1E4TAR0_9ASCO46.56%5093e-136Vacuolar protein sorting-associated protein 35 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_28229 PE=3 SV=1
VPS35_YEAST59.61%3071e-98Vacuolar protein sorting-associated protein 35 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VPS35 PE=1 SV=2
Q59T42_CANAL51.03%3391e-91Vacuolar protein sorting-associated protein 35 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=VPS35 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1364

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 911

Detailed signature matches

  1. Family IPR005378
    Vacuolar protein sorting-associated protein 35
    1. PF03635 (Vps35)
    2. PIRSF009375 (Retrom...)
  2. Domain IPR016024
    Armadillo-type fold
    1. SSF48371 (ARM repeat)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.30.70...
  3. mobidb-lite (disord...)

Protein sequence

>MCA_01858_1
MSSAVQIITAEEQARKLEESLSLIRHQEHLMRKCLESKGKLMDALKHASTFLTELRTSLLSPKQYYELYISVFDALSYLG
GYLRDNHNTYHLADLYELVQYAGNIVPRLYLMITVGTAYMSIPDAPVKEIMKDMIEMCRGVQHPIRGLFLRYYLSQTARD
NLPIGNSEGPEGNLQDSIQFIVTNFIEMNKLWVRLQHQGHSREREKRTKERKELQILVGSNLVRLSQLEGIDKEYYRSAI
LPAILEQVVQCRDVIAQEYLLDVVSQVFPDEFHLYTLDLFLNATANLHPQASVKKVILALVNRLADYAAREAENESSEKK
DGAADIVTKLASTKLDDSDKTETKKEDDEEKDGAKEKQESDDKKDDTPEDKEESTDKQEQAEDEKEIEKDEEDKDQKSSE
LSKASVTTRRGVPVDIDLFDIFWSFLSKLLTVRPDLPIEDITAILVGIARLTLNCYPDRIANADKILQFVLDKIEELKDT
PDAHSAETTGNILELLQLLIHSYPRMLTVLSLKNFIPLLESQPKKTQKAVASTVAEDVLKSGIQITTVEEVEGVFGLVRI
IICEGVDSLKNKPGVSDGLSGLMGDSADIAEDDKNISDEIVAGQGNLAKIIHLLYNKDPEIHAKLLTASRKALSEGGPFI
RYTYPALVTNSLRLVRRFKAREGVDKDWKEKIESTFKFVQIIINEINKVGSAEKALRLYVSSASVANQVGAEEAAYEYFV
EAFTIYEESISDSRAQYQAIVLIAGVLQSTRNFSPDSYDTLVSKCALYGSKLLKKPDQCRAVYLASHLWWAVEIPALGEQ
EDVTEFFRDGKRVLECLQRALRVADACMDAAVSVELFVEILNRYLYFFDRGNEKVTVKYITGLIELIQRNLDSMTTNDGS
ISDSPRKHFERTIQYINDQKEIDERFQAIVW

GO term prediction

Biological Process

GO:0015031 protein transport
GO:0042147 retrograde transport, endosome to Golgi

Molecular Function

GO:0005488 binding
GO:0008565 protein transporter activity

Cellular Component

GO:0030904 retromer complex