Protein
MIA_02497_1
Length
80 amino acids
Browser: contig03:970109-970470-
Protein function
| EGGNOG: | 0PSNH | DAD4 | Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore |
|---|---|---|---|
| SGD closest match: | S000007604 | DAD4 | DASH complex subunit DAD4 |
| CGD closest match: | CAL0000190531 | DAD4 | Dad4p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9XFD6_GEOCN | 55.556% | 72 | 8.72e-26 | Similar to Saccharomyces cerevisiae YDR320C-A DAD4 Essential subunit of the Dam1 complex (Aka DASH complex) OS=Geotrichum candidum GN=BN980_GECA13s02936g PE=4 SV=1 |
| MCA_01392_1 | 56.944% | 72 | 2.11e-24 | MCA_01392_1 |
| A0A1E4TA15_9ASCO | 44.444% | 72 | 4.24e-22 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_52620 PE=4 SV=1 |
| UniRef50_M7NMD0 | 47.222% | 72 | 6.12e-17 | Uncharacterized protein n=6 Tax=Fungi TaxID=4751 RepID=M7NMD0_PNEMU |
| A0A1D8PTL5_CANAL | 44.444% | 72 | 2.72e-18 | Dad4p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DAD4 PE=4 SV=1 |
| DAD4_YEAST | 41.667% | 72 | 3.83e-14 | DASH complex subunit DAD4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DAD4 PE=1 SV=1 |
| A0A1E3PRV7_9ASCO | 40.299% | 67 | 2.81e-13 | DASH complex subunit Dad4 (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_14373 PE=4 SV=1 |
| DAD4_YARLI | 34.667% | 75 | 2.79e-12 | DASH complex subunit DAD4 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=DAD4 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0724
Protein family membership
- DASH complex subunit Dad4 (IPR013959)
Domains and repeats
None predicted.
Detailed signature matches
-
-
PF08650 (DASH_Dad4)
-
Protein sequence
>MIA_02497_1 MENPHDQAQNALLVRITGNVEKLNEGIEYINRTLERIGKDNVEIETTTQAWENYMKSVKIHLENNGQMQPPLNPDSLEQS
GO term prediction
Biological Process
GO:0008608 attachment of spindle microtubules to kinetochore
Molecular Function
None predicted.
Cellular Component
GO:0042729 DASH complex
GO:0072686 mitotic spindle