Protein
MIA_02490_1
Length
476 amino acids
Browser: contig03:954931-956362+
Protein function
| EGGNOG: | 0PFPY | FG07019.1 | 3-hydroxyisobutyryl-CoA hydrolase |
|---|---|---|---|
| SGD closest match: | S000002443 | EHD3 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial |
| CGD closest match: | CAL0000174772 | EHD3 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_01644_1 | 61.975% | 476 | 0.0 | MCA_01644_1 |
| A0A0J9X434_GEOCN | 63.080% | 474 | 0.0 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Geotrichum candidum GN=BN980_GECA02s02331g PE=3 SV=1 |
| UniRef50_A0A0J9XIX1 | 59.348% | 460 | 0.0 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XIX1_GEOCN |
| A0A060SXR4_BLAAD | 53.249% | 477 | 0.0 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A11396g PE=3 SV=1 |
| A0A1E3PJK4_9ASCO | 53.153% | 444 | 2.24e-172 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46814 PE=3 SV=1 |
| A0A167EH75_9ASCO | 52.282% | 482 | 4.73e-168 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Sugiyamaella lignohabitans GN=EHD3 PE=3 SV=1 |
| Q6CA37_YARLI | 47.269% | 476 | 3.69e-150 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D06215g PE=3 SV=1 |
| A0A1E4TAJ0_9ASCO | 51.786% | 448 | 1.23e-149 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3410 PE=3 SV=1 |
| Q5AI24_CANAL | 38.961% | 462 | 6.93e-98 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=EHD3 PE=3 SV=1 |
| HIBCH_YEAST | 36.364% | 462 | 1.45e-80 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EHD3 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.7355
Predicted cleavage: 19
Protein family membership
- Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type (IPR032259)
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
400
450
476
Detailed signature matches
no IPR
Unintegrated signatures
-
-
cd06558 (crotonase-...)
Residue annotation
-
substrate binding ...
-
oxyanion hole (OAH...
-
trimer interface c...
Protein sequence
>MIA_02490_1 MTLRAKINPNMLPALARNNSSASSSSSDADDVLFAPNRAIRTITLNRPAKLNSLNQSMVDKIIPRMVEWTKSDTAQSVIL KGAGNKALCAGGDVAALAKDIANNGPEGSARSTVFFKDEYTLNHLIASYPKPYVAVMNGITMGGGVGLSVHAPFRIATEK TLFAMPETDIGFFPDVGGSFFLSRLDGQIGTYLALTSARLKGYDAVAAGIATHYIPESLLPEVESRLAEVFVDSVAPIDA HSLVNSVLLEFEAAAPEGYVFSLSGKARESIDAAFSNNTAEEIVAALEADGSDIAKAALKAILSRSPTAVKVTLAALRRG KSLGIKDALDAEYRLAENFMYGHEFVEGVSAKLISKPARAPEWKPATLQEVTPDIVNGYLSNRPDSVVQDIEFIHPENNF IEYPHTFGLPSEQQIQDYVLGNDNPDREFKVSAQEIHEHFDNISRGKLGVSQKINDVLSRKTKPDTTDAQLLDWIY
GO term prediction
Biological Process
GO:0008152 metabolic process
Molecular Function
GO:0003824 catalytic activity
GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity
Cellular Component
None predicted.