Protein

MIA_02483_1

Length
561 amino acids

Browser: contig03:939302-940988+

Protein function

EGGNOG:0PFJ1FG00875.1lysyl-tRNA synthetase
SGD closest match:S000002444KRS1Lysine--tRNA ligase, cytoplasmic
CGD closest match:CAL0000184486MSK1Lysine--tRNA ligase

Protein alignments

%idAln lengthE-value
A0A0J9XAZ4_GEOCN62.268%5380.0Lysine--tRNA ligase OS=Geotrichum candidum GN=BN980_GECA07s04916g PE=4 SV=1
MCA_05348_150.000%5981.03e-160MCA_05348_1
A0A060TA79_BLAAD50.092%5456.06e-153Lysine--tRNA ligase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D21472g PE=4 SV=1
UniRef50_A0A060TA7950.092%5451.50e-149Lysine--tRNA ligase n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A060TA79_BLAAD
A0A1E3PPF6_9ASCO48.315%5342.38e-151Lysine--tRNA ligase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81709 PE=4 SV=1
A0A167FZ22_9ASCO51.974%4567.26e-136Lysine--tRNA ligase KRS1 OS=Sugiyamaella lignohabitans GN=KRS1 PE=4 SV=1
Q6C814_YARLI46.139%5315.66e-133YALI0D23639p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D23639g PE=4 SV=2
A0A1D8PQY7_CANAL36.940%5367.65e-102Lysine--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MSK1 PE=4 SV=1
SYKC_YEAST39.019%4692.17e-83Lysine--tRNA ligase, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KRS1 PE=1 SV=2
A0A1E4THC7_9ASCO39.121%4782.98e-83Lysine--tRNA ligase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_116458 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9966
Predicted cleavage: 50

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 561

Detailed signature matches

  1. Family IPR002313
    Lysine-tRNA ligase, class II
    1. TIGR00499
  2. Domain IPR012340
    Nucleic acid-binding, OB-fold
    1. SSF50249 (Nucleic a...)
  3. Domain IPR004365
    OB-fold nucleic acid binding domain, AA-tRNA synthetase-type
    1. PF01336 (tRNA_anti-...)
  4. Domain IPR006195
    Aminoacyl-tRNA synthetase, class II
    1. PS50862 (AA_TRNA_LI...)
  5. Domain IPR004364
    Aminoacyl-tRNA synthetase, class II (D/K/N)
    1. PF00152 (tRNA-synt_2)
  6. Domain IPR018149
    Lysyl-tRNA synthetase, class II, C-terminal
    1. PR00982 (TRNASYNTHLYS)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.40.50...
  2. G3DSA:3.30.93...
  3. SSF55681 (Class II ...)
  4. cd04322 (LysRS_N)

Residue annotation

  1. dimer interface cd...
  2. putative anticodon...

Protein sequence

>MIA_02483_1
MPSIVSMALARVMPKPWSRLSSLVLRSPYSSSKHPKHKSRAITPENEALDFANRKASLLASGSDLYPLLKPLPEAPRLRI
PAFRAEWTAHAPYVDNPYAVDAPQPPLFTVQGRIRTIRKSGKGLIFFDLIQDQTKLQVVINKTKANLSQELFDSAHAALR
RGDIVSCTGTPWITKSGELSLLADRPAQLLAPCFHPIPTNLTNETTRRHNRVIDLVANKPARDVLVVRSTVLAYVREFFT
HRGFLEVQTPMLADLASGATATPFVTHSKALSSDGNARELALRIAPELWLKRLVVAGFDKVFEVGQNFRNEGIDATHNPE
FTTCEFYKAYATLDDLVVLTQDLLRGLVERVAELHPELFSERVQQLRAAFAADFRAVDFVAEIESRAGLRLPADLSSVDA
LLEFYAQARVPPPGSLASAAKLLDGLAAHYLEPQSEGTFAPLLITNHPAAMSPLAKTDARTGLSRRFELFIDGKEFVNAY
EEENSPLAQRAKFAAQMRERTQFRDGEVPLPDESYVDALEWGLPPTGGWGLGVDRLCMLVTGSKRIEDVLAFGGVKAVNY
Q

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006430 lysyl-tRNA aminoacylation

Molecular Function

GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004824 lysine-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm