Protein

MIA_02444_1

Length
320 amino acids


Browser: contig03:821116-822389+

Protein function

EGGNOG:0PGG8FG09299.1ribose-phosphate pyrophosphokinase
SGD closest match:S000001003PRS3Ribose-phosphate pyrophosphokinase 3
CGD closest match:CAL0000176742PRS1Ribose phosphate diphosphokinase subunit

Protein alignments

%idAln lengthE-value
A0A0J9X736_GEOCN92.188%3200.0Similar to Saccharomyces cerevisiae YHL011C PRS3 5-phospho-ribosyl-1(Alpha)-pyrophosphate synthetase,synthesizes PRPP, which is required for nucleotide,histidine, and tryptophan biosynthesis OS=Geotrichum candidum GN=BN980_GECA04s02562g PE=4 SV=1
A0A060TA08_BLAAD90.625%3200.0ARAD1D19514p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D19514g PE=4 SV=1
MCA_05003_189.688%3200.0MCA_05003_1
A0A1E3PMX7_9ASCO87.539%3210.0Phosphoribosyl pyrophosphokinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82410 PE=4 SV=1
Q5ALK3_CANAL79.688%3202.76e-177Ribose phosphate diphosphokinase subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRS1 PE=4 SV=1
Q6C0G0_YARLI79.331%3291.11e-176YALI0F25047p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F25047g PE=4 SV=1
KPR3_YEAST78.750%3201.34e-172Ribose-phosphate pyrophosphokinase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRS3 PE=1 SV=1
UniRef50_P3868978.750%3203.21e-169Ribose-phosphate pyrophosphokinase 3 n=501 Tax=Opisthokonta TaxID=33154 RepID=KPR3_YEAST
A0A1E4TA52_9ASCO77.429%3194.96e-169Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3275 PE=4 SV=1
A0A167C485_9ASCO73.750%3202.21e-158Ribose phosphate diphosphokinase subunit PRS2 OS=Sugiyamaella lignohabitans GN=PRS2 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2322

Protein family membership

Domains and repeats

1 50 100 150 200 250 320

Detailed signature matches

    1. PF14572 (Pribosyl_s...)
    1. PF13793 (Pribosyltr...)
    1. SSF53271 (PRTase-like)
    1. cd06223 (PRTases_typeI)
    1. PS00114 (PRPP_SYNTHASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SM01400 (Pribosyltr...)

Residue annotation

  1. active site cd06223

Protein sequence

>MIA_02444_1
MSTNSIKLIAGDVHRGLAELVADRLGLKLCKVDVFRDSNRETSITIGESVRDEDVYIITQIGSGDVNDRILELLIMINAC
KTASARRITAVLPNFPYARQDRKDKSRAPITAKLMANMLETAGCNHVITMDLHASQIQGFFDVPVDNLYAEPSVVNYIKQ
TIDYNNAIIVSPDAGGAKRAAALADRLDLNFALIHKERARANEVSRMVLVGDVSDKICILVDDMADTCGTLAKAAETLLS
HNAQSVIAIVTHGILSGKATDIINKSRLASVVCTNTVPLEGKDQLSSKIATIDVSLVLAESIRRLHNGESVSYLFRNAPL

GO term prediction

Biological Process

GO:0009116 nucleoside metabolic process
GO:0009156 ribonucleoside monophosphate biosynthetic process
GO:0009165 nucleotide biosynthetic process
GO:0044249 cellular biosynthetic process

Molecular Function

GO:0000287 magnesium ion binding
GO:0004749 ribose phosphate diphosphokinase activity

Cellular Component

None predicted.