Protein

MCA_05003_1

Length
318 amino acids


Browser: contigD:76562-77937-

RNA-seq: read pairs 2067, FPKM 80.1, percentile rank 75.2% (100% = highest expression)

Protein function

KEGG:K00948PRPS ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
EGGNOG:0PGG8FG09299.1ribose-phosphate pyrophosphokinase
SGD closest match:S000001003PRS3Ribose-phosphate pyrophosphokinase 3
CGD closest match:CAL0000176742PRS1Ribose phosphate diphosphokinase subunit

Protein alignments

%idAln lengthE-value
MIA_02444_189.69%3200.0MIA_02444_1
A0A0J9X736_GEOCN88.44%3200.0Similar to Saccharomyces cerevisiae YHL011C PRS3 5-phospho-ribosyl-1(Alpha)-pyrophosphate synthetase,synthesizes PRPP, which is required for nucleotide,histidine, and tryptophan biosynthesis OS=Geotrichum candidum GN=BN980_GECA04s02562g PE=4 SV=1
A0A060TA08_BLAAD86.25%3200.0ARAD1D19514p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D19514g PE=4 SV=1
A0A1E3PMX7_9ASCO85.67%3210.0Phosphoribosyl pyrophosphokinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82410 PE=4 SV=1
Q6C0G0_YARLI81.46%3297e-179YALI0F25047p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F25047g PE=4 SV=1
Q5ALK3_CANAL79.38%3203e-174Ribose phosphate diphosphokinase subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRS1 PE=4 SV=1
KPR3_YEAST79.38%3204e-172Ribose-phosphate pyrophosphokinase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRS3 PE=1 SV=1
UniRef50_P3868979.38%3209e-169Ribose-phosphate pyrophosphokinase 3 n=501 Tax=Opisthokonta TaxID=33154 RepID=KPR3_YEAST
A0A1E4TA52_9ASCO78.06%3197e-166Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3275 PE=4 SV=1
A0A167C485_9ASCO75.31%3208e-160Ribose phosphate diphosphokinase subunit PRS2 OS=Sugiyamaella lignohabitans GN=PRS2 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2730

Protein family membership

Domains and repeats

1 50 100 150 200 250 318

Detailed signature matches

    1. PF14572 (Pribosyl_s...)
    1. PF13793 (Pribosyltr...)
    1. SSF53271 (PRTase-like)
    1. cd06223 (PRTases_typeI)
    1. PS00114 (PRPP_SYNTHASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SM01400 (Pribosyltr...)

Residue annotation

  1. active site cd06223

Protein sequence

>MCA_05003_1
MTSNSIKLLAGDVHRGLAELVAKRLGLKLAKIDVFRDSNTETSITIGESVRDEDVYIITQIGCGDVNDRILELLIMINAC
KTASARRITVVLPNFPYARQDRKDKSRAPITAKLMANMLETAGCNHVITMDLHASQIQGFFNVPVDNLYAEPSVVNYIKQ
NIDYTNAIIVSPDAGGAKRAAALADRLDLNFALIHKERARANEVSRMVLVGDVSDKICILVDDMADTCGTLAKAAETLLG
HDAKAVIAIVTHGILSGRATEIINSSKLTKVVCTNTVPFQNSSPKIATIDISMVLAEAIRRLHNGESVSYLFRNAPLE

GO term prediction

Biological Process

GO:0009116 nucleoside metabolic process
GO:0009156 ribonucleoside monophosphate biosynthetic process
GO:0009165 nucleotide biosynthetic process
GO:0044249 cellular biosynthetic process

Molecular Function

GO:0000287 magnesium ion binding
GO:0004749 ribose phosphate diphosphokinase activity

Cellular Component

None predicted.